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GlossaryDepression (Depressive Disorder)

persistent sadness and loss of interest affecting daily life

Depression, also known as Major Depressive Disorder (MDD), is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. It can also involve physical symptoms such as changes in sleep, appetite, and energy levels, and can significantly impair daily functioning.

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community Hair loss returned suddenly and rapidly after a year on only oral minoxidil? Hair getting greasy fast.

in Chat 10 upvotes 7 months ago

User experienced sudden, rapid hair loss after a year on 2.5mg oral minoxidil. They are hesitant to use finasteride due to anxiety and depression concerns.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 8 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 74 upvotes 4 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community started using minoxidil and my hair fall has stopped almost completely

in Minoxidil 24 upvotes 4 years ago

A user started using minoxidil and noticed a significant reduction in hair fall after two days. Other users expressed skepticism, suggesting that results typically take longer and may initially increase hair shedding.

community Fin and min saved my life 2021 vs 2024 (24 y/o)

in Progress Pictures 326 upvotes 7 months ago

A user shared their positive experience with finasteride and minoxidil for hair loss, noting significant improvement and regrowth after 1.5 years of treatment, despite initial side effects. They are now happy with their hair and personal life.

community Kintor’s KX-826 Pyrilutamide!!

in Research/Science 149 upvotes 3 years ago

KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.

community why do some people have such a severe personal vendetta against finasterid?

in Question 17 upvotes 6 years ago

A user is concerned about starting finasteride due to negative reports and potential side effects. Other users suggest talking to a doctor, considering personal tolerance, and note that side effects are rare.

community Any finasteride users have a history of depression?

in Finasteride/Dutasteride 26 upvotes 2 months ago

The conversation discusses finasteride for hair loss, especially among those with a history of depression. Users shared mixed experiences, with some reporting no issues and others experiencing worsened depression.

community Soon nearly 2 Years Finasteride+Minoxidil Update

in Progress Pictures 406 upvotes 9 months ago

The conversation is about a user sharing a nearly 2-year update on hair regrowth using finasteride and minoxidil, with occasional use of microneedling. Commenters are impressed with the significant improvement in the user's hair.

community Finasteride won’t make all your problems go away

in Finasteride/Dutasteride 323 upvotes 11 months ago

A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community After almost 4 months on fin, it looks like I might be unlucky enough to develop early sings of gyno...

in Finasteride/Dutasteride 6 upvotes 4 years ago

After nearly four months on finasteride, a user noticed improved hair quality but developed nipple puffiness, suggesting early signs of gynecomastia. They considered switching to other treatments like CB-03-01 or RU58841 and contemplated consulting an endocrinologist about aromatase inhibitors.

community European Medecine Agency (EMA) review of Finasteride and Dutasteride

in Finasteride/Dutasteride 37 upvotes 1 month ago

Concerns about a potential ban on finasteride and dutasteride due to side effects, with users advocating for continued access and informed choice. Alternative treatments like pyrilutamide are also mentioned.

community Massive study on finasteride side effects released

in Finasteride/Dutasteride 83 upvotes 1 year ago

The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

community Finasteride and Its Effects on Cognition: Where's the Science?

in Research/Science 29 upvotes 4 years ago

The user shared their experience with hair loss treatments, including low-dose minoxidil, finasteride, and essential oils, and expressed concerns about the cognitive side effects of finasteride. They are seeking more information on how finasteride may affect cognition and are considering whether to continue or stop the treatment.

community Hair started thinning and found out i have high cortisol and thyroid issues

in Treatment 8 upvotes 5 months ago

User experienced hair thinning due to high cortisol and thyroid issues, along with insulin resistance. They are taking magnesium, zinc, vitamin D, calcium, and selenium as supplements.

community I Get Side-Effects from Anti-Androgens

in Finasteride/Dutasteride 6 upvotes 4 years ago

Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community He used Dutasteride for 20 years. Interview

in Treatment 106 upvotes 4 days ago

community Oral Biotin and Topical Minoxidil have a synergy effect in increasing hair growth, the study was only done in healthy subjects and it was only 14 days but it does prove that biotin can play a significant role as an adjunct treatment.

in Research/Science 170 upvotes 1 month ago

Oral biotin combined with topical minoxidil may increase hair growth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.

community Why balding gets worse in every generation?

in Chat 81 upvotes 5 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community 8-months progress: dermarolling + supplements

in Progress Pictures 264 upvotes 6 months ago

A user shared an 8-month hair loss treatment progress using daily saw palmetto and biotin capsules, weekly dermarolling, and a scalp lotion mix of castor, jojoba, and rosemary oils, avoiding finasteride and minoxidil due to side effects and cost. The user reported encouraging progress with slight hairline improvement and better crown area, attributing most success to dermarolling.

community My barber noticed my progress 😁

in Update 208 upvotes 9 months ago

A user's barber noticed significant improvement in their hair thickness after they started using 2.5mg Minoxidil since August 2023 and 1mg Finasteride daily since September 2023. The user has experienced some headaches when missing Minoxidil doses but has not noticed major side effects.

community Dutasteride 2 years 3 month results

in Finasteride/Dutasteride 251 upvotes 1 year ago

The user tried dutasteride for hair loss for 2.5 years but experienced drastic thinning and receding hairline. They decided to switch back to finasteride, along with minoxidil, LLLT, and ketoconazole, due to dissatisfaction with dutasteride's results and side effects.

community Anyone else not have hobbies anymore because of this?

in Chat 117 upvotes 1 year ago

The user is expressing an obsession with hair loss and spends all their time researching and discussing it. Other users suggest seeking therapy and focusing on other aspects of life.

community When I’m 60 and finally off the fin after 40 years and look at my semen

in Satire 862 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Users share experiences with Finasteride, mentioning watery semen as a side effect and weighing its importance against maintaining hair.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 4 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community This is what some balding dudes are like

in Satire 1036 upvotes 3 weeks ago

Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 367 upvotes 3 weeks ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.