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GlossaryCytochrome P450 (CYP)

enzymes metabolize drugs and toxins in the liver

Cytochrome P450 (CYP) refers to a large family of enzymes that play a crucial role in the metabolism of various substances within the body, including drugs, toxins, and hormones. These enzymes are primarily found in the liver and are essential for the detoxification process, as well as the synthesis of cholesterol, steroids, and other lipids.

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community Insane Idea: Cyperus Rotundus Oil?

in Research/Science 9 upvotes 2 months ago

Cyperus rotundus oil is suggested as a natural treatment for androgenic alopecia, potentially inhibiting hair growth without affecting testosterone levels. The conversation questions its effectiveness and safety for scalp use.

community Cyproterone Acetate. Hair has stopped falling out ever since starting it. Is this a good sign?

in Transgender 6 upvotes 3 years ago

Cyproterone Acetate stopped hair loss and led to regrowth on the temples for a transgender individual, which is considered a good sign. Unlike Minoxidil and Finasteride, which can cause initial shedding, Cyproterone did not cause shedding.

community People who used cyproterone for hair loss

in Treatment 2 upvotes 1 year ago

The conversation discusses the use of 12.5mg cyproterone every other day for hair loss. There's a concern about reducing testosterone potentially increasing DHT and negatively affecting hair.

community Anyone who used topical bicalutamide/estradiol/cyproterone acetate /spironolacton? (Need advice)

in Treatment 6 upvotes 5 months ago

A user is seeking advice on the efficacy and side effects of homemade topical solutions for hair loss, specifically bicalutamide, estradiol, cyproterone acetate, and spironolactone, as they cannot access RU58841 or pyrilutamide.

community Treating male pattern baldness in a transgender woman using cyproterone acetate, finasteride and biotin.

in Finasteride 6 upvotes 8 years ago

The conversation discusses treating male pattern baldness in a transgender woman using cyproterone acetate, finasteride, and biotin. The original poster shared their experience for others who might be in a similar situation.

community 1 Year Estradiol HRT, Oral Finasteride, Bicalutamide, Cyproterone. (20MTF)

in Transgender 4 upvotes 1 year ago

The conversation discusses a 20-year-old transgender female's one-year experience with hair loss treatments, including Estradiol HRT, oral Finasteride, Bicalutamide, and Cyproterone. Specific treatments used for hair loss are oral Finasteride and potentially Estradiol as part of hormone replacement therapy.

community Oral vs Topical Finasteride for Trans Women

in Transgender 4 months ago

A user is using a Finoxidil topical spray and is curious if oral Finasteride would be more effective, considering they are already on a DHT blocker called Cyproterone. They are concerned about the potential impact of oral Finasteride on their transition.

community 5 months of nuking T, 2 months of minoxidil

in Transgender 491 upvotes 3 months ago

The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

community Hair follicles do die - my „hair“ is the proof of that statement.

in Female 8 upvotes 1 year ago

The user discusses their experience with hair loss despite taking estrogen and cyproterone, and estimates needing around 3000 grafts for a feminine hairline. They are considering getting the procedure done in Turkey due to high European costs.

community FUE 2990 Grafts (2 Day surgery) HDC Clinic Dr. Maras

in Transplants 23 upvotes 5 months ago

A 28-year-old man shared his experience with a 2990 graft FUE hair transplant at HDC Clinic in Cyprus, praising the professionalism and care received. He has been using topical Minoxidil, Biotin, Dermarolling, and recently started Finasteride and oral Minoxidil.

community Can anyone tell me if this might be dangerous or good for my hair/head/body ?

in Question 7 years ago

A user is asking if a new hair product, Cypress Premium Vials Energy and Cypress Premium Shampoo Energy, could be dangerous or worsen their hair condition. The product contains various ingredients including water, alcohol, menthyl lactate, and several extracts.

community 2 years of recovering & growing my hair

in Progress Pictures 2 upvotes 3 months ago

A user shared their 2-year hair recovery journey using minoxidil, microneedling, finasteride, iron, zinc, selenium, cyproterone, and estrogen. They started losing hair at 15 and are now 24.

community What do you think about this galenic lotion by my trichologist?

in Hair Systems 1 upvotes 3 months ago

The user discusses a galenic hair lotion containing progesterone, estradiol, cyproterone, hydrocortisone butyrate, and cetirizine pheniramine, which has effectively stopped their hair loss over two years. They are curious about the compatibility of finasteride with the lotion's components and note that their trichologist has successfully used minoxidil and finasteride in similar treatments for others.

community Any current RU58841 user experiences? I just added it to my nuclear stack.

in Treatment 10 upvotes 1 year ago

A 26-year-old individual treating hair loss since 19, using a regimen of Finasteride, Cyproterone, Oral Minoxidil, Microneedling, Dutasteride, and newly added RU58841. They're seeking advice from other RU58841 users about their experiences.

community Unorthodox recovery timeline - 2.5 years minoxidil, 0.5 years finasteride, 2 years HRT

in Progress Pictures 6 upvotes 1 year ago

The post discusses a user's successful hair recovery using minoxidil, finasteride, and hormone replacement therapy (HRT) with cyproterone acetate and estradiol. The user experienced significant improvement in hair density and hairline recovery.

community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

in Insane 29 upvotes 2 years ago

A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

community Spironolactone for hair loss??

in Product 6 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.

community Are these all the anti androgen products?

in Treatment 6 upvotes 1 year ago

The conversation lists hair loss treatments including finasteride, dutasteride, RU58841, pyrilutamide, breezula, and fluridil, and suggests ketoconazole as another option. Some users warn against using certain treatments like cyproterone acetate, bicalutamide, and spironolactone due to their strong anti-androgen effects and potential impact on masculinity.

community 30 mtf 6 month update. from balding and sad to buzzing and glad

in Transgender 14 upvotes 10 months ago

A 30-year-old MTF individual shared a 6-month update on hair loss improvement using minoxidil, retinol, and microneedling, along with lowering testosterone to reduce DHT. They reported positive results, feeling happier and more confident.

community How to turn tiny baby hairs into long, thick strands? Oral min, oral fin, mtf hrt

in Transgender 5 months ago

A 25-year-old MtF individual has been using oral finasteride, oral minoxidil, and MtF HRT to treat androgenic alopecia, resulting in significant hair regrowth. However, the regrown hairs remain thin and short, and they seek advice on how to make these hairs longer and thicker.

community How does finasteride leave your body?

in Chat 13 upvotes 8 months ago

Finasteride is metabolized in the liver and excreted through urine and feces. Users humorously discuss its excretion, with one joking about it being expelled through ejaculation.

community Any balding females? I need advice with coping :(

16 upvotes 8 years ago

A 27-year-old woman is struggling with hair loss, feeling self-conscious and seeking advice on coping. She mentions trying Minoxidil but is hesitant due to scalp issues and is looking for ways to regain confidence.

community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 1 year ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community How to BECOME a RESPONDER to Fin/Dut if you are not responding

in Finasteride/Dutasteride 307 upvotes 1 year ago

The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.

community 7 months - 7 months oral dutasteride 0.5mg, 5 months oral minoxidil 12.5mg - 34 year old male

in Progress Pictures 82 upvotes 1 year ago

Hair loss progress and treatments, specifically oral dutasteride and oral minoxidil.

community We need more people trying 2.5 mg dutasteride

in Finasteride/Dutasteride 2 upvotes 1 month ago

Increasing the dutasteride dose to 2.5 mg may significantly reduce DHT and promote hair regrowth, with similar side effects to lower doses. Some users combine dutasteride with minoxidil and finasteride for better results, but there are concerns about long-term effectiveness and availability.

community Is there any way at all to style what little hair i have left to make it look not awful?

in Transgender 1 upvotes 2 months ago

OP is struggling with hair loss and is seeking advice on styling or treating their hair to look better. They currently use Nizoral and Maui conditioner but are considering wigs due to the lack of improvement.

community 10 Months of Nuclear Stack [Dut, Min, Keto + Estradiol & Spironolactone (MtF HRT)] -- Does it need more time or does it need a transplant?

in Progress Pictures 6 upvotes 3 months ago

The post discusses using a combination of Dutasteride, Minoxidil, Ketoconazole, Estradiol, and Spironolactone for hair regrowth. Users suggest it needs more time and possibly a transplant, with some sharing personal experiences and side effects of similar treatments.

community NootBro Recommendations… How Do We Feel

in Research/Science 9 upvotes 6 months ago

The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

community For people that keep saying Breezula is weaker than fin...

in Finasteride/Dutasteride 6 upvotes 4 years ago

Breezula protects hair follicles from both testosterone and DHT, unlike finasteride, which only protects against DHT. This could potentially lead to significant hair regrowth, similar to results seen in transgender individuals using hormone blockers.