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Did you mean CRISPR-Cas system?

GlossaryCRISPR (CRISPR-Cas system)

gene-editing tool that precisely alters DNA sequences

CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary gene-editing technology that allows scientists to precisely alter DNA sequences within organisms. It utilizes the Cas9 protein to cut DNA at specific locations, enabling the addition, removal, or modification of genetic material, which has vast implications for treating genetic disorders, improving crops, and advancing biological research.

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community Why is nobody studying the difference between donor and balding hair?

Hairlssuf in Chat 89 upvotes 8 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community MicroRNA can regrow 90% of lost hair, researchers find

2fy54gh6 in Treatment 502 upvotes 2 years ago

Researchers finding that microRNA can potentially regrow 90% of lost hair, and the challenges involved in moving this research forward to human trials. Various treatments for hair loss, such as finasteride and minoxidil, have been discussed.

community What should we lookout for in the near future for hairloss?

Drakeprkr1 in Research/Science 17 upvotes 1 year ago

The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.

community 1y 2 mo of 0.5 mg fin daily, minox 5% and nizoral 2%. Just giving back to the community cuz Reddit saved me a year ago. Don’t lose hope, things do work out

in Progress Pictures 55 upvotes 2 years ago

The user's progress with hair loss treatments of 0.5mg finasteride daily, minoxidil 5%, and nizoral 2%. They discuss if further growth is possible, their experience after two months, and encourage others to not lose hope.

community Brutal... RU58841 , is that true ?

Worth-Beat-1953 in Update 162 upvotes 7 months ago

The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Concerns are raised about the lack of studies on RU58841 and its potential effects.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

Zeweny in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community TWIST-1 and the cure: Is it really that easy?

ProposalInside7538 in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community Have we become too obsessed with DHT??

itsnearlygone in Chat 12 upvotes 3 years ago

Focus on scalp health, not just DHT suppression, is crucial for hair regrowth. Effective treatments include Hair Restoration shampoo, LLLT laser cap, microneedling, and topical finasteride.

community Cure/better treatment options in the future

Vrxdical in Chat 11 upvotes 5 months ago

The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.

community Spanish dermatologist suggests sulforaphane for AGA

GreenFloyd77 in Research/Science 13 upvotes 1 year ago

A Spanish dermatologist suggests sulforaphane for androgenetic alopecia (AGA) due to its potential to remove DHT metabolites, though high dosages are needed. A topical formulation might be possible.

community Wet hair progress (4 months 1mg finasteride daily then 8 months .5mg dutasteride every 3rd day) with nizoral 3x per week

ggggg454545 in Progress Pictures 203 upvotes 3 years ago

User shared 12-month hair growth progress using finasteride and dutasteride, with nizoral 3x per week. They experienced a finasteride shed but saw improvement after a year and offered advice for managing hair loss expectations.

community Kintor Pharma Announces Completion of First Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China.

dannar2003 in Research/Science 133 upvotes 1 year ago

Kintor Pharma has started a Phase II trial in China for GT20029, a potential new treatment for hair loss. Participants are discussing the significance, potential release dates, and comparing it to other treatments and technologies like stem cell hair transplants and SAMIRNA.

community Why is it that low testosterone causes hair loss as well? How can I be balding?

Ends-here in Chat 158 upvotes 9 months ago

The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

noeyys in Technology 107 upvotes 4 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community When are we getting a cure to hair loss?

Glittering_Bid7606 in Chat 1 year ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community 22 years since the last major development

heraldomalso in Technology 50 upvotes 3 years ago

The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

hzah1 in Research/Science 35 upvotes 9 months ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community How do we only have two treatments to combat hair loss at this point in time?

NUS_BEE in Chat 211 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

hokq699 in Finasteride/Dutasteride 13 upvotes 2 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

Ant1pal in Progress Pictures 56 upvotes 3 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.

community My Last Hair Follicle Looking Up As I Pour The Most Vile Research Chemical

user10893432823432 in Satire 1746 upvotes 2 years ago

Treatments for hair loss, such as minoxidil, finasteride, and RU58841; humorous posts about hair loss; and the choice to stop using treatments in exchange for a different look.

community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

noeyys in Research/Science 211 upvotes 1 month ago

PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

community CRISPR treatment for AGA on the horizon after approval for blood disorders

noeyys in Treatment 9 upvotes 1 year ago

CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

Mr_Rolandas in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community Maintaining hair until Breezula without Fin

hairgodshavemercy in Treatment 6 upvotes 4 years ago

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

community Innovative hair loss treatment can restore 90% of lost hair

lenniekohen in Research/Science 887 upvotes 4 months ago

A new hair loss treatment using dermal exosomes can restore up to 90% of lost hair in mice. Users discuss potential human trials and compare it to Minoxidil and Finasteride.

community don't deny the truth you know in your heart of hearts

I_Never_Comment1804 in Satire 1851 upvotes 4 days ago

Hair loss treatments like finasteride, minoxidil, and ketoconazole shampoo are discussed humorously, with skepticism about future cures. Users express frustration over the lack of a permanent solution and joke about investing in stocks or using time travel to solve baldness.

community (Serious) News and discussion on potential treatments

First-Element in Treatment 26 upvotes 3 months ago

Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

community Should I dedicate my university studies to solving hair loss?

unithrowawaylol in Research/Science 373 upvotes 2 years ago

A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.

community I really hate how current hair loss treatment only rely on DHT blockers

Significant_Web1562 in Finasteride/Dutasteride 76 upvotes 1 year ago

The conversation discusses dissatisfaction with current hair loss treatments that mainly focus on DHT blockers like finasteride and dutasteride. Alternative treatments mentioned include RU58841, pyrilutamide, minoxidil, rosemary oil, and future possibilities like hair cloning.