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GlossaryPlacebo Group (Control Group)

group receiving an inactive substance to compare treatment effects

A Placebo Group is a set of participants in a clinical trial who receive a placebo—a substance with no therapeutic effect, often a sugar pill—rather than the active treatment being tested. This group serves as a baseline to compare the effects of the actual treatment, helping researchers determine whether the treatment's effects are due to the treatment itself or other factors. This is also known as a Control Group in many studies.

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community Exosomes increase by 46% the efficacy at 1 year of standard treatment for AAG using {Dutasteride 0.5mg/day + minoxidil 5mg/day}

in Product 6 upvotes 10 months ago

Adding exosomes to a treatment of dutasteride and minoxidil for hair loss increased hair count by 55% at 6 months and 46% at 1 year compared to the control group. The control group did not receive exosomes or PRP.

community Creatine's effect on Hair Loss and DHT

in Research/Science 102 upvotes 9 months ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community Any update on breezula? Or PTD - DBM

in Research/Science 9 upvotes 3 years ago

The conversation is about updates on hair loss treatments Breezula or PTD-DBM. No new information was provided.

community Hair Loss Breakthrough: Keratin Microsphere Gel Initiates Hair Regrowth in Days by Directly Targeting Follicles and Boosting Gene Expression - Gilmore Health News

in Treatment 463 upvotes 9 months ago

A new hair loss treatment involving Keratin Microsphere Gel is discussed, with skepticism and jokes about its effectiveness and comparisons to other treatments. Users are doubtful and make light of the situation, referencing past disappointments and the study's focus on mice.

community New study shows minoxidil tropical solution 5% can cause eyesight problems.

in Research/Science 183 upvotes 1 month ago

Minoxidil 5% topical solution may cause eyesight problems, with some users experiencing blurred vision. The discussion also mentions finasteride's potential side effects, including erectile dysfunction, with varied personal experiences.

community "When comparing 5% minoxidil with 0.60 mm or 1.20 mm needle lengths, Faghihi et al. found that 0.60 mm needle lengths led to significant hair count and diameter increases versus 5% minoxidil, whereas 1.20 mm needle lengths only saw hair count increases versus 5% minoxidil"

in Research/Science 60 upvotes 6 months ago

Microneedling with 0.6 mm needles combined with 5% minoxidil is more effective for hair count and thickness than minoxidil alone or with 1.2 mm needles. Biweekly microneedling at 0.6 mm depth is recommended for better results in treating androgenetic alopecia.

community Study: Dutasteride Mesotherapy Accelerates Hair Loss in Female Patients with Metabolic Syndrome

in Finasteride/Dutasteride 15 upvotes 9 months ago

Dutasteride mesotherapy in women with metabolic syndrome accelerated hair loss after initial regrowth, while women without metabolic syndrome saw continuous regrowth. The user with mild insulin resistance is hesitant to try topical dutasteride and seeks experiences from others with insulin resistance.

community New Study Fails to Show Benefits of Microneedling in Males with Balding.

in Treatment 157 upvotes 1 year ago

A new study suggests microneedling alone doesn't benefit male balding, but users argue the study's methods differ from common practices, like combining microneedling with minoxidil and using more frequent treatments. Some believe the study's short duration and infrequent sessions are inadequate to assess microneedling's effectiveness.

community Surprisingly thorough study on He-Shou-Wu/Fo Ti

in Research/Science 14 upvotes 1 year ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community "Minoxidil and Caffeine: Reason behind hyper responders and non-responders."

in Research/Science 31 upvotes 1 year ago

Minoxidil and caffeine may interact, affecting hair growth results. Users shared mixed experiences, with some noticing improvements without caffeine and others still seeing results despite coffee consumption.

community shampoo nizoral 1% information

in Ketoconazole 3 upvotes 1 year ago

User has itching, dandruff, and scalp issues, considering Nizoral 1% shampoo for treatment. Nizoral's effectiveness for hair loss is uncertain due to limited research, short contact time, and concentration differences.

community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

in Research/Science 126 upvotes 1 year ago

The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Tretinoin for better Minoxidil response

in Treatment 11 upvotes 3 years ago

The conversation is about using tretinoin to improve the response to Minoxidil for hair loss treatment. No specific protocol for tretinoin application is provided.

community (Study) Essential oils are effective for treatment of alopecia areta, could be effective for mbp.

in Treatment 2 upvotes 3 years ago

Essential oils like rosemary, thyme, lavender, and cedar wood in a carrier oil may effectively treat alopecia areata and potentially male pattern baldness by stimulating the scalp similarly to minoxidil. The user plans to try this routine and share results.

community how it feels to talk to tiktok kids about hairloss that isn’t shitty rosemary oil bloodflow and microneedling

in Satire 993 upvotes 2 months ago

Minoxidil and finasteride are effective for hair loss, especially when used together. Microneedling may enhance minoxidil's effects, but its standalone effectiveness is uncertain.

community Microneedling monotherapy shown more effective at 0.5mm than 1mm and 1.5mm in recent 6 month study

in Microneedling 135 upvotes 3 months ago

Microneedling at 0.5mm is more effective than at 1mm and 1.5mm for hair loss. Users discuss switching to 0.5mm and combining it with Minoxidil.

community Oral minoxidil + microneedling - pointless?

in Microneedling 19 upvotes 2 weeks ago

Oral minoxidil is considered effective for hair growth, and some users combine it with microneedling despite mixed opinions on its additional benefits. Concerns about microneedling include potential scarring and lack of conclusive evidence on its effectiveness when used with oral treatments.

community Can someone explain the science behind why Finasteride doesn't stop you from losing regrown hairs from minoxidil?

in Minoxidil 100 upvotes 3 weeks ago

Finasteride prevents further hair loss by blocking DHT, while minoxidil stimulates hair growth by prolonging the active phase of hair follicles. Stopping minoxidil can lead to loss of regrown hair because finasteride does not address the same growth mechanism.

community Microneedling to maintain results from min

in Microneedling 7 upvotes 2 months ago

Microneedling alone is not effective in maintaining minoxidil results for hair growth. Combining microneedling with minoxidil and finasteride may enhance results, but microneedling by itself is not a reliable treatment.

community I can’t believe what I’m actually seeing. 9 months progress.

in Finasteride/Dutasteride 577 upvotes 3 months ago

A 26-year-old male shared his 9-month hair regrowth progress using 1mg oral finasteride daily, 5% topical minoxidil once a day, and weekly 1.5mm microneedling. He reported no side effects and significant improvement, with users discussing various experiences and advice on similar treatments.

community Pyrilutamide just launched internationally, and all you're doing is hating

in Product 4 months ago

The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

community Finally about to start Pyriltamide (ONLY Pyriltamide)

in Chat 63 upvotes 4 months ago

A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

community Kintor (Koshine Biomedica) changed their KX-826 pictures on Amazon to a alleged study picture after backlash over fake pictures

in Product 118 upvotes 4 months ago

Kintor changed their KX-826 pictures on Amazon after backlash over fake images. Users are skeptical about the product's effectiveness and trustworthiness, with some preferring finasteride instead.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 5 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community does dermarolling work with oral minoxidil?

in Microneedling 9 upvotes 5 months ago

The conversation discusses whether dermarolling (microneedling) works with oral minoxidil for hair loss treatment. References to studies on microneedling alone and combined with minoxidil are provided.

community The Secret Recipe? How do celebrities do it?

in Research/Science 7 upvotes 6 months ago

Celebrities often maintain perfect hairlines through expensive transplants and common drugs like finasteride and dutasteride. Despite potential side effects, the importance of their appearance makes these treatments worthwhile.

community 3.5 months progress - oral dut 0.5mg and oral min 5mg - 26M

in Progress Pictures 143 upvotes 7 months ago

A user reports hair regrowth and thickening after 3.5 months using oral dutasteride (0.5mg) and oral minoxidil (5mg). They express gratitude for the information received from the community about hair loss treatments.

community So is GT20029 available on the grey market anywhere?

in Treatment 16 upvotes 8 months ago

The conversation discusses the availability of GT20029, a new topical hair loss treatment with fewer side effects than Minoxidil or finasteride. Users suggest using finasteride to preserve hair until GT20029 becomes available.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 8 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.