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Glossary Contraindications

situations where a treatment should not be used due to harm

Contraindications refer to specific situations or conditions where a particular treatment, medication, or procedure should not be used because it may be harmful to the person. For example, if someone is allergic to a certain drug, that drug would be contraindicated for them. In the context of hair treatments, a contraindication might be a scalp infection that would make certain chemical treatments unsafe.

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community How can I get Dut without a prescription?

7 upvotes 1 week ago

A woman with advanced AGA is seeking ways to obtain Dutasteride without a prescription due to difficulties with traditional methods and concerns about birth defects, despite being celibate and on birth control. Users suggest various online sources and alternatives like topical anti-androgens, while cautioning about potential risks and side effects.

community Do any of you guys use both oral AND topical minoxidil simultaneously?

41 upvotes 1 week ago

The conversation discusses using both oral and topical minoxidil for hair loss, with some users reporting mixed results and concerns about potential side effects. The original poster uses topical finasteride and oral minoxidil and is considering adding topical minoxidil and tretinoin to their regimen.

community ashwagandha while taking finasteride

6 upvotes 9 months ago

The user is considering taking ashwagandha while on finasteride to manage side effects, noting it reduces stress but may cause hair thinning. They are unsure if the thinning is due to ashwagandha or normal shedding from finasteride.

community Why is my dermatologist strictly against derma stamping/derma rolling?

in Microneedling 27 upvotes 1 year ago

Dermatologists often advise against at-home microneedling due to risks of scarring, infection, and improper technique. Professional guidance is recommended for safe and effective use, with some users reporting positive results when done correctly.

community Looking to make my own 2-Deoxy-D-ribose. Any science bros can give advice?

7 upvotes 2 years ago

A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.

community Do I Disagree With Dr. Who Says Hair Loss Cause is Female Pattern Baldness and not Iron Deficiency? (25 Female)

5 upvotes 5 years ago

A 25-year-old woman is experiencing hair loss and is unsure if it's due to iron deficiency or female pattern baldness, as diagnosed by her dermatologist. She is considering using Minoxidil but is hesitant and seeks advice on whether increasing her iron levels could help.

community Clavicular, The Daily, and what his rise means for hair

5 months ago

The conversation critiques the influence of "Clavicular" on young men regarding hair loss treatments, highlighting the dangers of following unscientific advice and the rise of body dysmorphia. It emphasizes the importance of safe, medically advised treatments like minoxidil, finasteride, and dutasteride, while warning against reckless experimentation and early surgeries.

community Minoxidil and concern about cats

5 upvotes 1 year ago

Minoxidil is highly toxic to cats, and even small amounts can be fatal. The user decided against using topical minoxidil due to the risk to their cats and considered oral minoxidil and ketoconazole shampoo as alternatives.

community 10mg Minoxidil - 3 months progress

141 upvotes 1 week ago

A 29-year-old male in Australia has been using 10mg of oral minoxidil for almost three months, experiencing significant hair growth but also hair growth on other body parts. He was prescribed this dosage without requesting it and has not experienced side effects, though others in the conversation express concern about the high dosage and suggest considering finasteride or dutasteride.

community Do you think oral minoxidil will become the standard for hair loss in 2026?

139 upvotes 7 months ago

Oral minoxidil is considered more convenient and effective for some users, with positive results reported, but concerns about side effects and availability persist. Finasteride remains a standard treatment, while some users explore combinations with other treatments like dutasteride and laser devices.

community Feeling the 2nd, perhaps 1st, Dutasteride shed, might shave, might thug it out.

in Progress Pictures 67 upvotes 1 year ago

The user is experiencing increased hair shedding after 6 months of using Dutasteride and oral minoxidil, despite previous regrowth and satisfaction with the results. They are considering shaving their head again and discuss the effectiveness of their treatment routine, which includes Dutasteride, oral minoxidil, and Nizoral, while also addressing concerns about side effects like erectile dysfunction and body composition changes.

community Any concrete cases of people who were told they couldn't have a transplant because of microneedling?

in Hair Systems 26 upvotes 2 years ago

Microneedling before a hair transplant may harden the scalp and affect blood circulation, potentially impacting graft growth. Some users report successful transplants after microneedling, while others advise caution and consulting with a surgeon.

community If dutesteride and oral minoxidil doesn’t work that’s it right?

in Treatment 41 upvotes 2 years ago

A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Five Month Progress

3 upvotes 5 years ago

A 33-year-old male shared his hair regrowth journey, using minoxidil, dermarolling, hair brushing, scalp oils, dietary changes, and supplements. After five months, he started finasteride to improve hair thickness.

community It’s 2026, gentlemen. Let’s finally settle this: Does Dermarolling/Microneedling actually work…YES or NO?

56 upvotes 7 months ago

Microneedling, especially when combined with minoxidil, is generally considered effective for hair regrowth, though results vary by individual. Some users report enhanced results, while others caution about potential scarring and recommend professional guidance.

community No fearmongering /just facts on yesterday someone posting on eye issues

in Finasteride/Dutasteride 33 upvotes 1 year ago

Finasteride and dutasteride may not significantly impact meibomian gland function since these glands do not rely on DHT. Some users report dry eyes and other side effects from finasteride, but these may be influenced by other factors or medications.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 16 upvotes 1 year ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community Extreme caution: my experience using Ru58841 only once

in Treatment 10 upvotes 1 year ago

An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

community Spironolactone vs finasteride - advice for female with AGA

2 upvotes 10 months ago

Spironolactone and finasteride are not recommended for women planning pregnancy due to birth defect risks. Both need to be stopped months before conception, and finasteride is generally not advised for women.

community Reminder: You cannot donate blood if you are taking Fin or Dut

730 upvotes 1 year ago

You cannot donate blood if you are taking finasteride or dutasteride due to potential risks to pregnant women. Finasteride has a shorter wait time to donate blood compared to dutasteride, and both oral and topical forms can disqualify you from donating.

community Why are there no proper phase 3 trials for RU

in Chat 4 upvotes 5 months ago

RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

community A warning to anyone considering 3rd party sourcing PP405 or its analogs

30 upvotes 5 months ago

Be cautious when sourcing PP405 or its analogs from third-party suppliers due to potential safety risks and lack of regulatory approval. The conversation highlights concerns about counterfeit products and the absence of reliable testing, making it risky to use such treatments.

community PSA: You can’t donate blood if you are taking finasteride

in Finasteride/Dutasteride 280 upvotes 10 months ago

Finasteride users cannot donate blood due to potential risks to pregnant women, requiring a one-month cessation before donating. Dutasteride requires a six-month deferral, and topical applications are not restricted.

community How can I safely apply RU58841 whilst I have children in the house?

in Treatment 8 months ago

RU58841 is not recommended for use around children due to potential exposure risks. Alternatives like CB-03-01 might be considered, but further research is advised.

community Spironolactone and pregnancy planning

in Female 2 upvotes 1 year ago

A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

community Can those who had Hair Transplant use PP405 and Clascoterone? Scalp blood supply limitation question

8 upvotes 9 months ago

Using PP405 and Clascoterone after a hair transplant may not cause issues if the transplant didn't achieve native density, but could lead to competition for blood supply if it did. Some users suggest waiting for these drugs to be available, as they might not significantly impact blood supply or regrowth.

community Bleeding too much for other reasons

7 upvotes 3 years ago

The user experienced excessive bleeding during microneedling after consuming caffeine and THC, and is unsure if they should continue with the same routine. They are seeking advice on whether the bleeding is a cause for concern.

community Doubtful of RU58441's negative effects

in Research/Science 2 upvotes 1 year ago

RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

26 upvotes 3 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.