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      community Amplifica and AMP-303 clinical phase 1

       9 upvotes 2 years ago
      Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

      community M35, diffuse thinning and HT possibilities

       5 upvotes 2 weeks ago
      A 35-year-old male is experiencing diffuse thinning and is using finasteride, topical minoxidil, and dutasteride. He is considering a hair transplant but is advised to wait and continue with medications for now.

      community Riken develops new method for culturing hair follicles

       41 upvotes 8 years ago
      A new stem cell method for culturing hair follicles is being developed as an alternative to Minoxidil, finasteride, and RU58841. There are concerns about its cost and accessibility despite plans for commercialization.

      community Finasteride is not working

       11 upvotes 6 years ago
      Finasteride is not effectively stopping hair loss for the user, who is considering alternatives like Dutasteride, Minoxidil, and microneedling, but is hesitant about surgery or hair systems. The user expresses frustration with the lack of effective treatments for male pattern baldness.

      community How do you use Fin or Dut and not bottom out your DHT ?

       1 upvotes 4 weeks ago
      A female user experiences severe side effects from topical finasteride and pumpkin seed oil for hair loss, leading to rapid hair thinning after stopping use. She seeks advice on tapering off treatments to manage hair sensitivity and maintain hair health.

      community Help On Topical Finasteride 0.3%

       2 upvotes 2 years ago
      A user is seeking advice on a new topical hair loss treatment containing Minoxidil 3%, Finasteride 0.3%, Progesterone 1%, Hydrocortisone butyrate 0.1%, and Ketoconazole 0.5%. They are concerned about the systemic absorption of Finasteride and plan to do blood tests and a spermiogram before starting.

      community Taking cordyceps while on dutasteride?

       1 upvotes 2 years ago
      The conversation discusses concerns about using cordyceps while on dutasteride due to potential DHT increase, with OP experiencing hair loss after using creatine. OP is advised to stop creatine and give dutasteride more time to evaluate its effectiveness.

      community Federal Grant Cuts have impacted PP405 related research

       459 upvotes 1 year ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community just found out dutasteride powder isn’t being absorbed properly

       4 upvotes 3 months ago
      The user is frustrated because their current dutasteride treatment isn't effective due to poor absorption, leading to hair loss progression. They consider switching to gel capsules and discuss using minoxidil and biotin alongside dutasteride.

      community Diffuse thinner, would I respond well to a hair transplant?

       29 upvotes 3 weeks ago
      The user is experiencing diffuse thinning and has started taking 0.5mg dutasteride and 5mg oral minoxidil daily, planning to wait a year before considering a hair transplant. They are advised to be patient, consult with doctors, and see how the medication affects their hair density before proceeding with surgery.

      community Clascoterone powder already available?

       4 upvotes 5 months ago
      Clascoterone powder is now available, but it's expensive and not widely discussed due to past ineffective results at higher concentrations. Users are skeptical about its effectiveness and are seeking reliable sources.

      community Bicalutamide effect on androgens?

       5 upvotes 5 years ago
      Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

      community Topical Finasteride Pill filler

       3 upvotes 7 months ago
      Users discuss making topical finasteride solutions by dissolving crushed tablets in ethanol and propylene glycol, with concerns about residue affecting effectiveness. They also mention using minoxidil and oral finasteride, noting some hair regrowth and no side effects from topical use.

      community hairloss treatment, what to expect (bloodwork)

       1 upvotes 11 months ago
      The conversation discusses hair loss treatment options, focusing on finasteride and its potential effects on gynecomastia. The user is considering finasteride while managing hormone levels with supplements like boron, vitamin D, zinc, magnesium, and P5P, and is advised to consult an endocrinologist for further evaluation.

      community Oral minoxidil dark circles. Did this improve over time for you?

       6 upvotes 1 month ago
      Oral minoxidil caused dark circles and visible veins for the user, who responded quickly to the treatment but lowered the dose to reduce side effects. Despite using finasteride and tretinoin, the user is considering stopping minoxidil if the side effects persist.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 7 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community Starting fin / minoxidil progress so far

       62 upvotes 3 months ago
      The user started using finasteride and minoxidil for hair loss, noting past success with minoxidil alone but now needing a DHT blocker. They experienced side effects like chest pain and considered reducing the finasteride dose.

      community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

       26 upvotes 3 years ago
      Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

      community Minoxidil has been both a blessing and a curse

       153 upvotes 2 months ago
      Minoxidil can cause dark circles and aging appearance in some users, leading them to stop its use despite hair regrowth benefits. Some users suggest reducing dosage or switching to oral minoxidil to minimize side effects.

      community what type of hair brush do diffused thinners use

       4 upvotes 2 weeks ago
      The conversation is about hair loss and the type of hair brush used by those experiencing diffused thinning. The discussion includes treatments like Minoxidil, finasteride, and RU58841.