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GlossarySkin Pigmentation (Complexion)

natural color of skin determined by melanin levels

Skin pigmentation, also known as skin color or complexion, refers to the natural color of a person's skin, which is primarily determined by the type and amount of melanin produced by melanocytes in the epidermis. Melanin is a pigment that provides protection against ultraviolet (UV) radiation. Variations in skin pigmentation can be influenced by genetic factors, sun exposure, and certain medical conditions.

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community Certified old, at 51, balding since 25, the resurrection!

in Progress Pictures 439 upvotes 4 weeks ago

A 51-year-old shared progress on hair regrowth using topical Minoxidil and Finasteride over four months, noting significant improvement and plans for future hair transplants. The user emphasized the benefits of modern treatments and societal changes in attitudes towards hair loss.

community Are most men bald because they haven’t tried any treatment or are they bald in spite of it?

in Shaved/buzzed 307 upvotes 7 months ago

Some men are bald because they are unaware of hair loss treatments like Minoxidil (Min) and Finasteride (Fin), while others choose not to use them due to potential side effects, cost, or personal preference. Treatments like Min and Fin are discussed, with varying results and opinions on their effectiveness and side effects.

community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 8 months ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community 2 months progress. Hair is shorter in the first pic, same length in the second and third.

in Progress Pictures 294 upvotes 1 year ago

User reports 2 months progress using daily oral fin 1mg, twice daily topical min 5%, and intermittent dermapen. Others share their experiences, suggesting patience and additional treatments like alternating shampoos, using conditioner, tretinoin, and vitamins.

community Decided to go for hair transplant after a few months of really thinking it through. I can say it was one of the best decisions I’ve made in my life

in Progress Pictures 491 upvotes 1 year ago

User decided to get hair transplant and is happy with results. Others compliment the change and suggest hair loss concealers or SMP for further improvement.

community Got my first hair system put on yesterday. I feel like a brand new man. Haven’t been confident in so many years.

in Hair Systems 385 upvotes 3 years ago

User got first hair system and feels confident. Cost $200, attached at hairclub for $150, considering $400 monthly membership for weekly visits and new system monthly.

community Life after minoxidil? Has anyone stopped

in Update 147 upvotes 5 months ago

A user stopped using minoxidil after 10-12 years due to severe side effects like fluctuating blood pressure and chest pain, resulting in significant hair loss. Other users shared similar experiences, emphasizing health over hair and suggesting alternatives like finasteride, nanoxidil, and rosemary oil.

community Hair Transplant Results from Asli Tarcan Clinic (Afro Hair)

in Progress Pictures 511 upvotes 8 months ago

A user shared their positive hair transplant results from Asli Tarcan Clinic in Turkey, costing $3,500 for 6,000 grafts and resulting in a full head of hair. They also take finasteride and dutasteride to maintain their hair.

community 1 year of finasteride, minoxidil (capsules) and rosemary oil. (Side note I also… lost weight, had a LOT of therapy for unresolved childhood trauma and started arresting my unhelpful thinking/ useless self hatred/ judging myself and others/ hair loss) 🥹

in Progress Pictures 1013 upvotes 10 months ago

The user shared a one-year progress of treating hair loss with finasteride, minoxidil capsules, and rosemary oil, and also improved mental health by addressing childhood trauma and changing negative thought patterns. Commenters congratulated the user on both hair regrowth and mental health progress, with one asking for advice on overcoming self-hatred and low confidence.

community I'm considering scalp micropigmentation, has anyone here done it? If yes, did you regret it, how did it affect you?

in SMP 107 upvotes 1 year ago

User considers scalp micropigmentation (SMP) for hair loss. Mixed opinions shared; some regret it, others satisfied. Choosing reputable clinic and technician is important.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community Oral Minoxidil Users In A Nutshell

in Satire 1209 upvotes 2 years ago

This conversation is about hair loss treatments, specifically oral minoxidil and finasteride. Users discussed the potential side effects of using these drugs, as well as their experiences with them.

community Can I punch someone if they make fun of my hair loss, just like Will Smith did?

in Chat 448 upvotes 2 years ago

Hair loss's social impact, focusing on Will Smith defending Jada Pinkett Smith's alopecia. The conversation highlights double standards between men and women experiencing hair loss and emphasizes empathy.

community Oral minoxidil may not be as dangerous as what people say

in Minoxidil 9 upvotes 4 years ago

The safety of using oral minoxidil to treat hair loss and thinning, with studies showing mild side effects at low doses. It was suggested that people should consult a doctor or dermatologist before taking any type of medication for hair loss.

community If you’re sitting there wondering, “I’m losing my hair, what do I do?” then read my advice here. I’ve been fighting the fight for 7 years, with great success. (pictures included)

in Question 106 upvotes 11 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community NW5 at 19. How many grafts do I need?

in Transplants 140 upvotes 1 year ago

A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

community Kintor Pharma Announces Completion of Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China

in Research/Science 89 upvotes 1 year ago

Kintor Pharma completed patient enrollment for a Phase II trial in China for GT20029, a potential new treatment for hair loss. Some believe GT20029 could replace finasteride if effective, while others discuss finasteride's limited efficacy and potential underreported side effects.

community Kintor Pharma Announces Completion of First Patient Enrollment in KX-826 Long-term Safety Phase III Trial for Treatment of AGA

in Research/Science 12 upvotes 1 year ago

Kintor Pharma has finished enrolling the first patient in a Phase III trial for KX-826, a treatment for androgenetic alopecia (AGA). One user has set a reminder to check back on the topic in a year.

community Kintor Pharma Announces Successful Completion of Phase II Clinical Trial of KX-826 for Treatment of Androgenetic Alopecia in the US

in Research/Science 23 upvotes 1 year ago

Kintor Pharma completed a successful Phase II clinical trial for KX-826, a treatment for androgenetic alopecia. KX-826 is similar to finasteride with minor side effects and is more backed than Cosmerna.

community Kintor Pharma Announces Successful Completion of Phase II Clinical Trial of KX-826 for Treatment of Androgenetic Alopecia in the US

in Research/Science 122 upvotes 1 year ago

Kintor Pharma announced successful Phase II trial results for KX-826 in treating hair loss, showing it's comparable to finasteride and can be used with it. Some participants saw a 10 hair/cm^2 increase, which is considered a good outcome at the low dose used.

community Kintor Pharma Announces Completion of First Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China.

in Research/Science 132 upvotes 1 year ago

Kintor Pharma has started a Phase II trial in China for GT20029, a potential new treatment for hair loss. Participants are discussing the significance, potential release dates, and comparing it to other treatments and technologies like stem cell hair transplants and SAMIRNA.

community Kintor Pharma Announces Completion of Subject Enrollment in Phase III Clinical Trial of KX-826 for Treatment of Male Androgenetic Alopecia

in Research/Science 80 upvotes 1 year ago

Kintor Pharma completed enrolling subjects for a Phase III trial of KX-826 for male hair loss treatment. The trial includes a 24-week treatment period and a 4-week safety follow-up, with results expected in about 6-7 months.

community Kintor Pharma Announces Completion of Subject Enrollment and Dosing in Phase I Clinical Trial of AR-PROTAC(GT20029) in the US_Kintor Pharmaceutical Limited

in Research/Science 60 upvotes 2 years ago

Kintor Pharma finished enrolling and dosing participants in a Phase I trial for a hair loss treatment called AR-PROTAC (GT20029). The effectiveness of another drug, pyrilutamide (KX-826), for hair loss will be clearer after a Phase 2 trial expected to complete in January 2023.

community Cassiopea announces completion of recruitment of Phase II dose ranging trial of Breezula (CB-03-01) for androgenic alopecia

10 upvotes 6 years ago

The conversation discusses the completion of a Phase II trial recruitment for Breezula (CB-03-01), a potential treatment for androgenic alopecia. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Setipiprant study updated on ClinicalTrials - anticipated May 9th completion

20 upvotes 6 years ago

The conversation discusses hair loss treatments, specifically Setipiprant, finasteride, and bimatoprost. Setipiprant is suggested for maintenance, while bimatoprost is for regrowth, and combining them with dermarolling is recommended for better results.

community HMI-115 Australian Phase 1 Trial completed?

in Research/Science 20 upvotes 1 year ago

The post discusses the completion of the HMI-115 Australian Phase 1 Trial for hair loss treatment. The user speculates about the potential early release of the trial results.

community Cosmo Pharma Lists Breezula Phase 3 Trial on ClinicalTrials.gov

in Research/Science 26 upvotes 1 year ago

A phase 3 trial for Breezula (clascoterone solution) to treat male pattern hair loss has been listed, with 726 participants and a completion date of January 2025. Other treatments mentioned include Aneira Pharma's combination of minoxidil and latanoprost, Triple Hair's combination of minoxidil, latanoprost, and finasteride, and a new microneedling and LLLT device called StimuSIL.

community Has HMI-115 finished Phase I? Hope Medical website shows possible completition.

in Research/Science 11 upvotes 1 year ago

The progress of Phase I of HMI-115, a potential hair loss treatment, which consists of Minoxidil, finasteride, and RU58841. The estimated completion date is June.

community Kintor pyrilutamide presentation?

in Research/Science 12 upvotes 2 years ago

The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

community "When comparing 5% minoxidil with 0.60 mm or 1.20 mm needle lengths, Faghihi et al. found that 0.60 mm needle lengths led to significant hair count and diameter increases versus 5% minoxidil, whereas 1.20 mm needle lengths only saw hair count increases versus 5% minoxidil"

in Research/Science 60 upvotes 5 months ago

Microneedling with 0.6 mm needles combined with 5% minoxidil is more effective for hair count and thickness than minoxidil alone or with 1.2 mm needles. Biweekly microneedling at 0.6 mm depth is recommended for better results in treating androgenetic alopecia.