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GlossaryCentral Nervous System (CNS)

brain and spinal cord controlling body's activities and responses

The Central Nervous System (CNS) consists of the brain and spinal cord, serving as the main control center for the body. It processes sensory information, coordinates voluntary and involuntary actions, and is crucial for functions such as thought, emotion, and movement.

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community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 2 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Pyrilutamide US Phase 2 Trial?

in Research/Science 27 upvotes 2 years ago

The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.

community The most depressing things about hair loss for me

in Chat 23 upvotes 3 years ago

The emotional impact of hair loss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.

community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas

in Research/Science 21 upvotes 4 months ago

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

community Dutasteride Literally Saves Your Hair

in Finasteride/Dutasteride 96 upvotes 5 months ago

Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

community Why does it seem everyone favors finasteride over dutasteride?

in Female 62 upvotes 6 months ago

The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

community My journey from Norwood 3.5/4 to Norwood 0

in Transplants 255 upvotes 8 months ago

A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 8 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 9 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.