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GlossaryChordin

protein regulating embryonic development by inhibiting BMPs

Chordin is a protein that plays a crucial role in early embryonic development by regulating the formation of the body's axis. It functions by binding to and inhibiting Bone Morphogenetic Proteins (BMPs), which are involved in cell differentiation and tissue formation. This inhibition helps establish the dorsal-ventral axis, essentially guiding the development of the back and belly sides of an organism.

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community Question for those people applying topical pyril (or ru) and another topical like min (or min/fin), what's your regimen?

in Research/Science 9 upvotes 1 year ago

The conversation is about the difficulty of applying both pyril and min/fin to treat hair loss twice daily and whether combining them yields positive results.

community We don’t actually know what’s going on.

in Treatment 212 upvotes 4 months ago

Hair loss treatments vary greatly in effectiveness and timelines, with no guaranteed results. Common treatments mentioned include finasteride, minoxidil, and RU58841.

community Progress but at different times?

in Is this regrowth? 6 upvotes 5 months ago

The user has been taking 1.25mg of oral minoxidil and 1mg of finasteride for a year and added topical minoxidil in January. They noticed hair improvement but are experiencing uneven regrowth, with the hairline improving and the middle part worsening.

community "Dutasteride Ruined My Hairline!"

in Finasteride/Dutasteride 36 upvotes 7 months ago

The user has been on dutasteride for six months and experienced significant hair shedding, especially at the hairline, and is seeking advice. Some suggest continuing the treatment and being patient, while others share mixed experiences with dutasteride and consider switching back to finasteride or adding other treatments like RU58841.

community I hate it when people write off your hairloss info because “you’re not a doctor.”

in Treatment 76 upvotes 1 year ago

A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hair loss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.

community Drone shots: fin 1 week vs. 4 months 👀

in Progress Pictures 797 upvotes 1 year ago

The post is about a user sharing progress pictures of their hair loss, comparing the appearance of their crown before and after using finasteride for 1 week to 4 months. The user also mentions using minoxidil and starting microneedling.

community Topical Dutasteride 1% - High dosage?

in Finasteride/Dutasteride 6 upvotes 1 year ago

User asks about two topical dutasteride solutions and wonders if 1% concentration is overkill compared to 0.1%. They also consider trying standard topical dutasteride before using Minoxidil.

community Kevin Mann(Haircafe) is the GOAT

in Update 416 upvotes 4 months ago

A user praised Kevin Mann for his hair loss advice, crediting finasteride and minoxidil with tretinoin for saving their hair. Other users shared similar experiences and expressed frustration over Mann's channel being affected by past controversies.

community Topical fin (0.008%) + min - left: 26yo, right: 30yo, goodbye MBP, I keep my NW-0 :D

in Progress Pictures 343 upvotes 6 months ago

A user shared progress pictures showing successful hair retention using a low-dose topical finasteride (0.008%) combined with minoxidil. Users discussed the effectiveness of the treatment, minimal effective dosing, and avoiding systemic side effects.

community Why don’t people just just DUT instead of FIN?

in Finasteride/Dutasteride 48 upvotes 7 months ago

The conversation discusses the use of dutasteride (DUT) versus finasteride (FIN) for hair loss treatment, with some users preferring DUT for its effectiveness while others choose FIN due to its approval status, better long-term data, and lower risk of side effects. Users share personal experiences with both medications, including side effects and effectiveness.

community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

in Research/Science 63 upvotes 7 months ago

The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

community Never had better results than a few drops of minoxidil under the tongue. I've tried various combinations.

in Minoxidil 12 upvotes 1 year ago

The user reports the best results for hairline regrowth using 3 drops of minoxidil under the tongue once daily, after trying various treatments including loniten, topical minoxidil with estrogen, dutasteride, and finasteride. Additional regimen includes occasional tretinoin, collagen peptides, crude oil massages, violet ray device, nizoral, and Listerine for scalp health.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 6 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.