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GlossaryCYP11A1 (Cholesterol Side-Chain Cleavage Enzyme)

enzyme converting cholesterol to pregnenolone, initiating steroid hormone production

CYP11A1, also known as Cytochrome P450 Family 11 Subfamily A Member 1 or P450scc, is an enzyme crucial for the production of steroid hormones. It catalyzes the conversion of cholesterol to pregnenolone, the first step in the biosynthesis of all steroid hormones, which are vital for various bodily functions including stress response, immune function, and regulation of inflammation.

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community How to BECOME a RESPONDER to Fin/Dut if you are not responding

in Finasteride/Dutasteride 302 upvotes 1 year ago

The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 484 upvotes 2 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community 48M, 11 month progress, 1MG finasteride only

in Progress Pictures 627 upvotes 1 year ago

A 48-year-old man's 11-month progress using 1mg finasteride for hair loss treatment, with significant improvement and no side effects. Other users share their experiences, with some also seeing positive results, while others have not been as successful.

community A warning to those using or thinking about using Dutasteride – Follow-up

in Finasteride/Dutasteride 18 upvotes 3 years ago

The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.

community Guys maybe high cholesterol and hair loss are related

in Chat 4 months ago

High cholesterol may accelerate hair loss by reducing blood flow and increasing DHT levels. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

in Research/Science 531 upvotes 7 months ago

The conversation discusses the potential benefits of finasteride (Fin) for lowering cholesterol and reducing cardiovascular disease risk, with users sharing personal experiences and opinions on the medication's effects on health and hair loss. Some users report positive changes in cholesterol levels after taking finasteride, while others are skeptical or joke about its effects.

community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly

in Update 6 upvotes 3 years ago

User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 787 upvotes 1 year ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community Why am I so scared to start fin?

in Finasteride/Dutasteride 15 upvotes 2 years ago

User is scared to start finasteride for hair loss due to potential side effects and personal concerns. Another user suggests trying a low dose for 6 months and avoiding online groups to reduce anxiety.

community I am putting my hair loss treatment on hold until my mental health is better.

in Update 18 upvotes 1 month ago

OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 2 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community Anti-Androgens causing hairline to recede?

in Research/Science 5 upvotes 2 months ago

Anti-androgens like Finasteride, Dutasteride, Metformin, and Topical Spironolactone cause hairline recession and increased cholesterol levels. The hairline recovers after stopping the drugs.

community Finasteride 1.25mg 10 month Progress

in Progress Pictures 149 upvotes 7 months ago

The user shared a 10-month hair loss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.

community Impressed by the progress but think it’s time to go for the transplant?

in Progress Pictures 288 upvotes 8 months ago

The user started taking 2.5mg minoxidil tablets daily and reduced their finasteride dose to 0.5mg due to side effects. They are considering a hair transplant but are unsure if they should proceed now or wait after seeing the effects of the reduced finasteride dosage.

community We are manipulating our hormones, surely it's prudent to track bloodwork ?

in Finasteride/Dutasteride 64 upvotes 5 months ago

The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.

community Is this true? Is long term taking fin harmful to the liver?

in Chat 127 upvotes 8 months ago

The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).

community New Dutasteride Long Term Study (5 years) it works.

in Finasteride/Dutasteride 106 upvotes 10 months ago

The conversation discusses a five-year study on dutasteride, a medication for male hair loss. The study found that 89.9% of patients saw improvement or prevention of hair loss progression, with varying success rates based on different balding patterns. Side effects were mostly sexual and decreased over time. Dutasteride was concluded to be a long-term, safe, and effective treatment for male hair loss.

community how does my progress look 18M 3 months on fin 1mg daily

in Progress Pictures 277 upvotes 10 months ago

An 18-year-old male's successful hair regrowth after three months of using finasteride 1mg daily. He reported no side effects and other users expressed admiration and curiosity about his results.

community Dutasteride 2 years 3 month results

in Finasteride/Dutasteride 251 upvotes 11 months ago

The user tried dutasteride for hair loss for 2.5 years but experienced drastic thinning and receding hairline. They decided to switch back to finasteride, along with minoxidil, LLLT, and ketoconazole, due to dissatisfaction with dutasteride's results and side effects.

community Long term results are real: 11 years on fin. then dut. + min. then oral min. - first pic at 18 with massive miniaturization and the others last night at 29

in Progress Pictures 758 upvotes 1 year ago

The conclusion of the conversation is that the user, who has been using finasteride for 11 years and then switched to dutasteride and minoxidil, has experienced minimal side effects and significant hair regrowth. They also mention that side effects are rare and often related to other factors such as poor diet and low testosterone levels.

community Got my bloodwork done today, I have been on fin for 7+ months. 21m

in Update 32 upvotes 1 year ago

A user on finasteride for 7+ months shared bloodwork results, questioning if high DHT levels and testosterone could affect cholesterol. Replies suggest consulting a doctor and question the high testosterone levels.

community Testosterone before and after take fin/dut

in Finasteride/Dutasteride 239 upvotes 1 year ago

User experienced 100% testosterone increase after using Finasteride and Dutasteride for hair loss. Some users discuss potential side effects and reasons for the increase.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Finasteride is one of the best decisions I ever made

in Finasteride/Dutasteride 306 upvotes 1 year ago

This conversation is about the effectiveness of Finasteride and Minoxidil as treatments for hair loss, with SnooBooks5080 claiming positive results from using both medications. However, other participants in the conversation caution that there are potential side effects to be aware of when taking Finasteride and advise people to do their research before making a decision.

community Finasteride gyno experience and in dire need of advice

in Finasteride/Dutasteride 7 upvotes 4 years ago

A user experienced puffy nipples and lumps from finasteride, leading to a dilemma between continuing treatment with potential surgery or accepting hair loss. They restarted finasteride at a lower dose with supplements but still face side effects and are seeking advice on whether to persist or stop.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 4 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 35 upvotes 5 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

community If you’re sitting there wondering, “I’m losing my hair, what do I do?” then read my advice here. I’ve been fighting the fight for 7 years, with great success. (pictures included)

in Question 106 upvotes 11 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 7 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community [M39] Minoxidil 5%, Finasteride 1mg, Microneedling 1.5mm and Ketoconazole

in Progress Pictures 235 upvotes 1 year ago

The conclusion of the conversation is that the user, PirateBeastBaby, had good results with microneedling for hair loss after using oral finasteride and topical minoxidil 20 years ago. They believe that microneedling was the gamechanger for their hair growth.