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      community How does dutasteride regrowth work?

      in Finasteride/Dutasteride  7 upvotes 2 years ago
      A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Why is clascosterone (cb0301) so expensive ?

       3 upvotes 1 month ago
      Clascosterone (CB0301) is expensive due to concentrated form and lack of market competition. Users discuss sourcing from Indian and Chinese pharmacies for cheaper alternatives, but express concerns about product quality.

      community topical cetirizine to control scalp inflammation

       4 upvotes 4 years ago
      The user applies a topical solution containing minoxidil, finasteride, dutasteride, retinoic acid, and hydrocortisone to address scalp inflammation and is considering adding cetirizine to the mix. They are calculating the correct amount of cetirizine to add to their formula and have paused this approach to retry oral minoxidil.

      community Any Indians using Minichek F 5% ???

       2 upvotes 2 years ago
      A user asks about experiences with Minichek F 5% with Procapil, specifically its drying time. Responses discuss the effectiveness and drying time of the treatment.

      community Has anyone tried CB-01-03 aka Clascoterone?

       2 upvotes 6 months ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Ben Greenfield Podcast : CHK-Cu & C-60

       4 upvotes 5 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.

      community Clascoterone 5% solution infographic

       130 upvotes 9 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community PP405 (Everychem 3HP) Users - Assemble and share your story!

      in Chat  19 upvotes 4 months ago
      Users discussed the effectiveness of Everychem's solution, similar to PP405, with some reporting improved hair thickness and new growth. Concerns were raised about safety and the legitimacy of the product, with some users advising against purchasing research chemicals.

      community Stemoxydine bad for collagen?

       2 upvotes 2 years ago
      Concerns about stemoxydine potentially inhibiting collagen synthesis. The user uses oral finasteride and ketoconazole shampoo for hair loss.

      community clascoterone powder to topical diy

       4 upvotes 4 months ago
      The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

      community What’s your views on clascoterone 5% topical solution by cosmo

       23 upvotes 9 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community How to mix raw Clascoterone (CB-03-01)?

       7 upvotes 2 months ago
      Mixing clascoterone with minoxidil involves using 99% ethanol and propylene glycol. Users discuss the effectiveness and potential side effects of this DIY solution.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

      community European release of clascoterone

       13 upvotes 4 months ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

       46 upvotes 1 month ago
      Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

      community Got prescribed clobetasol propionate 0.05%

       5 upvotes 3 days ago
      The user is experiencing diffuse thinning and receded hairline, using dutasteride, minoxidil, and ketoconazole without regrowth, and was prescribed clobetasol propionate 0.05% with salicylic acid for possible inflammation. Other users caution against using the strong steroid without a serious condition, sharing experiences of adverse effects and alternative treatments for scalp issues.

      community RU and cetosomal minoxidil topical

       1 upvotes 7 months ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community Oxytocin Pathway and Cinnamic Acid Research

       14 upvotes 2 years ago
      The conversation discusses the potential of cinnamic acid for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.

      community Don't use PP405 from everychem. it is likely fake.

       63 upvotes 1 year ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

       4 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.