RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.
The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.
The user shares their experience with a hair system, noting no one noticed the change except their girlfriend. They discuss the learning curve, maintenance tips, and their satisfaction with the results, feeling more confident and optimistic.
The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.
A user shared their progress after taking 1mg oral finasteride daily for a year, reporting significant hair improvement without side effects. They recently started oral minoxidil and made dietary changes, including cutting out gluten and processed foods, and taking supplements like multivitamins and zinc.
The user is experiencing increased hair shedding despite using oral dutasteride and a topical solution with minoxidil, finasteride, and tretinoin. They are considering switching to oral minoxidil while continuing dutasteride to address the shedding and seek advice on this potential change.
The user is experiencing increased hair shedding and is considering switching from a topical solution containing minoxidil, finasteride, and tretinoin to oral minoxidil while continuing oral dutasteride. They are seeking advice on whether this change could improve results and if the recent shedding could be due to a 2-week interruption in dutasteride.
The user "OP" is frustrated with hair loss despite using oral minoxidil, topical finasteride, and oral dutasteride. Other users suggest keto shampoo, lifestyle changes, and low light laser therapy.
OP has been using minoxidil (topical 5%) and finasteride (oral 1.25mg daily) for 2 months and is unsure if there's hair regrowth or if it's just a haircut illusion. Mixed responses from others, some see progress, others attribute changes to the haircut.
Low-dose oral minoxidil shows mixed results, with some users experiencing hair regrowth and others seeing no significant change. Finasteride is also commonly used, often in combination with minoxidil, and is generally considered effective with a low rate of side effects.
A 26-year-old male with a family history of early baldness documents his hair loss journey, using finasteride, dutasteride, and Nizoral, along with lifestyle changes like weightlifting and a vertical diet. Despite some stabilization, he continues to experience thinning and remains determined to fight hair loss.
A user started taking Dutasteride and experienced significant shedding initially, but it has since stopped after three months. They noticed some changes but are unsure if they are solely due to Dutasteride.
RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.
If oral minoxidil 2.5mg and finasteride 1mg fail after a year, some suggest trying dutasteride. Hair shedding can be normal in the first year, and real changes often occur between 9 months to a year.
User has been using topical Minoxidil (5%) and Finasteride (0.1%) for 5-6 months, along with a dermaroller. No side effects reported, but user notes weight gain without change in diet or exercise.
The post and conversation discuss KX-826 (pyrilutamide) for hair loss treatment, with positive remarks about its advertising and authenticity in China. The user changed their perspective after further research and seeing genuine advertising.
A user shared their two-year progress using 1mg finasteride, topical minoxidil, and occasional microneedling, noting no significant changes but a halt in hair loss progression. They recently started oral minoxidil and are considering a hair transplant.
User shared a 3-month progress update on hair loss treatment using finasteride and minoxidil. They experienced initial shedding, thicker hair growth, and facial breakouts likely due to hormone changes.
The conversation humorously discusses starting treatments like finasteride, dutasteride, RU58841, and oral minoxidil for hair loss. It highlights the challenges and experiences associated with these treatments.
The user experienced hair thinning, possibly due to long COVID and prediabetes, and saw regrowth after dietary changes and using biotin shampoo. They are taking vitamins and noticed significant hair regrowth, especially at the widow's peak.
A user shared their hair regrowth journey from age 21 to 25 using finasteride and a carnivore diet. Other users debated the effectiveness of diet changes versus genetic factors in hair loss.
Users discussed adding microneedling to minoxidil treatment for hair loss. Some saw improvements, especially when combining microneedling with minoxidil and finasteride, while others did not notice significant changes.
A user discusses their hair thinning journey, starting minoxidil at 16, switching treatments, and experiencing significant shedding after resuming minoxidil. They are now using minoxidil daily and considering PRP if shedding continues, while also planning lifestyle changes to improve their condition.
A user is losing hope after 5 months on finasteride, seeing more hair loss and minimal positive changes. Another user advises that shedding is normal and benefits may take up to 2 years.
The user started taking multivitamins, derma rolling, using rosemary oil, and taking 0.5mg finasteride daily. They noticed slight hair improvement and are questioning if the changes are due to finasteride or the other treatments.
The user follows a hair loss treatment routine including Propecia, oral minoxidil, ketoconazole, and plans to switch to dutasteride. They also focus on lifestyle changes, dietary supplements, and are considering laser therapy.
A user shared their progress with hair regrowth using a topical solution of 0.3% finasteride and 6% minoxidil spray. They asked for additional routine suggestions, but a reply suggested no changes if the current routine works.
A user shared their 2-year hair regrowth journey using finasteride, ketoconazole shampoo, and a diet change, without a hair transplant. Despite skepticism from others, the user insists the results are natural and encourages consistency and dietary adjustments.
A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.
Hair loss treatments include Minoxidil, Finasteride, hair transplant surgery, PRP therapy, laser therapy, natural remedies, and lifestyle changes. Combining treatments often yields the best results.