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      community Cetirizine (Zyrtec), to help with inflammation.

       3 upvotes 2 years ago
      The user experiences an itchy scalp and finds relief using shampoo and Zyrtec, which helps with inflammation. They are unsure if the issue is related to histamines or seborrheic dermatitis.

      community PP405 mechanism question - looking for discussion

       7 upvotes 5 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community month and a half update,

       4 upvotes 5 years ago
      The user is experiencing severe hair shedding after using RU58841, stemoxydine, and minoxidil, and has stopped using finasteride due to side effects. They hope the shedding is temporary and will lead to regrowth.

      community Thinking about using PP405 and RU58841

       1 upvotes 8 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Topical Anti Androgens detailed thread

       6 upvotes 1 month ago
      Users discuss the effectiveness of topical anti-androgens like RU58841, Pyri (KX826), and CB for hair loss. Some report maintenance and regrowth with Pyri, while others find limited success with RU58841 and switch to combinations like finasteride and minoxidil or minoxidil and dutasteride.

      community I found that Zyrtec solution for hair

      in Chat 4 weeks ago
      The conversation discusses using Cetirizine oral solution topically on the scalp to alleviate burning sensations caused by minoxidil. The user is curious about others' experiences with this method, while others suggest that only finasteride and minoxidil are effective for hair growth.

      community Any good experiences with Alfatradiol ?

       4 upvotes 6 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 7 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Looking for the new RU58841 source in EU

      2 years ago
      The user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and ask for advice on shipping within the EU and product quality, while also mentioning their current hair loss treatment involves mixing RU with Stemoxydine and Alfatradiol.

      community Red light therapy that works well

       5 upvotes 1 year ago
      Red light therapy with dual wavelengths (650nm and 850nm) can stimulate hair regrowth without DHT blockers. Consistent use of a panel with these wavelengths has shown positive results in hair regrowth.

      community KX-826 Phase 3 Failed. Sorry guys...

       51 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Another Verteporfin video popped up

       6 upvotes 1 year ago
      Dr. Toyos is recruiting more participants for a larger trial on hair loss treatments. The discussion mentions Minoxidil, finasteride, and RU58841 as potential treatments.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      5 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community Peter h diamandis Dr David Sinclair podcast

      6 months ago
      Hair loss treatments discussed include Minoxidil, finasteride, and RU58841. There is skepticism about claims of a breakthrough, despite FDA approval for human trials.

      community AHK-cu peptides experiences and sources to buy

       5 upvotes 1 year ago
      AHK-cu peptides are discussed for hair growth, with users comparing them to GHK-cu peptides and sharing sources to buy. AHK-cu is noted as more expensive, and users express interest in finding cheaper, reliable vendors.

      community What the hell happened to Breezula?

       13 upvotes 1 year ago
      Breezula (clascoterone) Phase 3 hair loss trial results are delayed, with no official updates yet. The acne version is approved, but hair loss results are still pending.

      community Anyone tried switching from RU to Pyrilutamide (KX-826)

       7 upvotes 8 months ago
      The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.

      community Potentially Positive Pyrilutamide News Coming

       6 upvotes 6 months ago
      Kintor Pharmaceutical's stock rise suggests potential positive news about Pyrilutamide, a topical anti-androgen. GT20029 may also compete with existing treatments like finasteride and dutasteride.