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      community Thoughts on new drug PP405? Already reached phase 2

       26 upvotes 1 year ago
      PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

      community Rate my stack! (Using a nuclear protocol)

       17 upvotes 5 years ago
      A hair loss regimen involving Dutasteride, Oral Minoxidil, Mesotherapy, Topical Minoxidil/Finasteride, RU58841, Alfatridiol, Microneedling, LLLT, Keto shampoo, Vitamin K/D/Fish oil/Borage Oil/MSM, Oral Castor oil and Niacin. It also mentions products that have been dropped from the regimen due to not being worth the hassle or messing with libido.

      community Topical ( Fin+Min+Arginine) wow?

       9 upvotes 2 years ago
      The conversation is about hair loss treatment using topical minoxidil, finasteride, and arginine, showing noticeable progress in one month. The user suggests adding arginine serum for better results.

      community What’s the view on stemoxydine?

       6 upvotes 1 year ago
      Stemoxydine may work synergistically with minoxidil and finasteride for hair growth, but its effectiveness is debated, with some users experiencing minimal results and concerns about cost. Users suggest sticking to proven treatments like minoxidil and finasteride, while considering stemoxydine as an additional option.

      community Going for mixology with fingers crossed.

      in Treatment 1 year ago
      The user is experimenting with a mix of topical treatments, including finasteride and minoxidil, to improve hair growth, particularly at the temples and core. They are also trying various oils, despite skepticism about their effectiveness, to see if they can enhance results without causing harm.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 8 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community I just made 60x of 5mg minoxidil sugar cubes

       1339 upvotes 1 year ago
      A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

       245 upvotes 2 years ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community Has anyone tried CB-01-03 aka Clascoterone?

       2 upvotes 6 months ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Increased efficacy of fin/dut: with or without meal?

       6 upvotes 4 months ago
      Taking dutasteride with a meal containing fat may improve absorption, but consistency in routine is more important than timing. Minor variations in absorption won't significantly affect efficacy due to dutasteride's long half-life.

      community PP405 Never Worked: the follicles were already activated at baseline

       17 upvotes 3 months ago
      PP405 was ineffective for hair growth as some follicles were already active before treatment, raising doubts about its efficacy. Users discussed other hair loss treatments like Minoxidil, finasteride, and RU58841, expressing skepticism and hope for future solutions.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

      community when is kintor going to start phase 3 for gt20029?

       6 upvotes 2 years ago
      The conversation is about the timeline for Kintor's phase 3 trials for GT20029 and the potential release of the product in three years. It also mentions treatments like Minoxidil, finasteride, and RU58841.

      community Creatine and ru-58841 experiences?

       1 upvotes 1 year ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Creatine paired with Finasteride

       22 upvotes 1 year ago
      Finasteride and creatine are discussed for hair loss, with mixed opinions on creatine's impact. Some users report no hair loss with creatine, while others experience shedding, but finasteride is generally seen as effective.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

       1 upvotes 7 months ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community Better Than Minoxidil? Topical Sodium Valproate

       50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Things to do besides treatment to see even more regrowth?

       8 upvotes 1 year ago
      The conversation discusses hair regrowth strategies, including using dutasteride, minoxidil, finasteride, dermastamping, soy, curcumin, and possibly castor oil. Suggestions also include increasing dutasteride dosage, using oral minoxidil, topical finasteride, and tretinoin to enhance minoxidil efficacy.

      community New article on PP405..........

      in Research/Science  109 upvotes 1 year ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community PP405 Updates Feel Like Breadcrumbs at This Point

       11 upvotes 3 months ago
      PP405 updates are seen as vague and lacking substance, causing frustration among users. Some users report positive effects from using minoxidil and dutasteride, while others remain skeptical about new treatments.