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Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.

Dutasteride may be better for the brain than Finasteride, potentially increasing dopamine levels and causing fewer side effects. For those switching from Finasteride to Dutasteride to prevent hair loss, it's recommended to continue Finasteride for 3-4 months while starting Dutasteride to avoid shedding due to Dutasteride's long half-life.

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

User experienced severe brain fog and anxiety from oral dutasteride and is considering dutasteride injections with PRP for hair loss, while currently using finasteride and oral minoxidil. They seek others' experiences with dutasteride mesotherapy and its side effects.

The user experienced headaches and brain fog with a topical solution containing Dutasteride, Minoxidil, Tretinoin, Fluocinolone, Latanoprost, and Caffeine. They are considering switching to oral or topical Finasteride to see if it alleviates these side effects.

User experienced hair thinning after losing 100 lbs and started Dutasteride treatment. They faced side effects like fatigue, brain fog, and insomnia but no erectile dysfunction.

The conversation discusses the difficulty in distinguishing between side effects of finasteride (like brain fog and loss of libido) and depression caused by hair loss. Users share experiences of severe depression while on finasteride, leading some to stop the treatment despite anxiety over hair loss.

A user discusses switching from RU58841 to Pyrilutamide due to side effects like fatigue, brain fog, and elevated heart rate. They have used dutasteride, finasteride, and minoxidil, and are seeking safer alternatives.

The user shared their 6-month progress using minoxidil and finasteride for hair loss, noting some brain fog and dizziness as possible side effects. They stopped derma-rolling and using nizoral shampoo, and other users commented positively on the results.

A 26-year-old user shared their 3-month progress using oral finasteride and oral minoxidil for hair loss. They experienced side effects like reduced libido and brain fog at higher doses and adjusted their dosage to manage these effects.

A user is considering switching from finasteride to dutasteride for hair loss at age 21, worried about potential side effects on bone and brain development. Another user shared their positive experience with dutasteride, noting minimal body hair and no side effects.

The individual reversed their hair loss using oral dutasteride and topical minoxidil, and experienced side effects including low libido, tiredness, and brain fog. They started treatment at age 26 and have a high-protein diet and exercise regularly.

A user shared their positive 1-year hair regrowth results from using dutasteride after 10 years on minoxidil and 2 years on finasteride, noting stronger hair, less brain fog, and better mood. They experienced initial shedding but saw improvements, including longer hair life cycles, and plan to continue monitoring progress.

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

User made progress with hair loss using Fin, Min, and microneedling. Experienced side effects like improved skin, brain fog, and memory issues, but adjusting Fin dosage helped.

The user experienced side effects from ecklonia cava similar to those reported with finasteride, including depression, brain fog, anxiety, and testicular pain. Despite these issues, the user is still considering using topical finasteride in the future.

The user switched from finasteride to dutasteride and added oral minoxidil, which helped regrow their hairline and reduce shedding. They experienced side effects like brain fog, sluggishness, and fat gain with dutasteride, and slight chest tightness with oral minoxidil.

The conversation concludes that finasteride, a 5α-Reductase inhibitor used for hair loss, does not impair cognition either short-term or long-term. It suggests "brain fog" is not caused by the medication.

Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

A 30-year-old man with diffuse hair thinning shared his hair regrowth regimen, which includes increasing Vitamin D intake, taking oral castor oil, using a dermapen, and various supplements like Glycine, K2, Vitamin E, Vitamin C, Aspirin, Sodium Bicarbonate, and a multivitamin. He also mentioned inconsistent use of Minoxidil, Peppermint Oil, Zix, and topical Castor Oil, and negative side effects from Finasteride, RU58841, and Nizoral.

Hair loss discussion includes finasteride issues resolved by switching to dutasteride. Specific treatments mentioned: Minoxidil, Finasteride, and RU58841.

Hair loss treatments discussed include Minoxidil, Finasteride, microneedling, red light therapy, and biotin pills. The most proven treatments are Minoxidil, Finasteride, and microneedling, while other methods are considered less effective or satirical.

Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

The conversation is about using Verteporfin with microneedling as a potential hair loss treatment that may regenerate hair follicles with minimal scarring. There are concerns about the optimal dosage and the DHT sensitivity of the new follicles.

Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.

A 30-year-old man has been using Minoxidil for years with limited success and recently started Finasteride, experiencing minor side effects but hoping for regrowth. Other users suggest not overthinking, considering a buzz cut, and being patient for results.

The conversation is about hair loss and treatments. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.

A user reported less hair shedding using melatonin spray and is considering trying topical oxytocin or estrogel for hair growth, but is concerned about potential side effects like breast development. Topical oxytocin has been found to promote hair growth by increasing growth factors.

A 25-year-old is using vinpocetine to enhance the absorption of topical Minoxidil for hair loss. They also use a hair tonic and supplement with Glycine, Taurine, Creatine, and Citrulline.