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Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

A user discusses their experience with at-home microneedling at 1mm for hair growth, feeling like they're hitting their skull. Other users suggest lowering the needle depth or stopping due to discomfort.

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

Oral minoxidil may deplete collagen, potentially causing skin aging. Users discuss whether taking collagen supplements can counteract this effect.

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

A user who had two hair transplants and is still concerned about their crown area, despite other people reassuring them that it looks normal. The advice given was to use Minoxidil, Finasteride, SMP, and to consider speaking with a therapist.

Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.

User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

A user is considering switching from finasteride to dutasteride for hair loss at age 21, worried about potential side effects on bone and brain development. Another user shared their positive experience with dutasteride, noting minimal body hair and no side effects.

A user is concerned about the legitimacy of a hair growth serum called Lavdik, which they ordered after seeing an ad for Jemros. The product contains ginger extract, ginseng extract, fleece flower root, grape seed oil, glycerol, carbomer, propylene glycol, and rosemary oil, and the user is unsure if it is effective or a scam.

Vitamin D deficiency is linked to hair loss, and supplementation with vitamin D can improve conditions like androgenic alopecia and telogen effluvium. Users discussed various dosages of vitamin D, emphasizing the importance of getting blood tests to determine the appropriate amount.

User shared 18-month progress using 1 mg finasteride daily and varying doses of oral minoxidil. Minoxidil caused side effects managed with taurine, dandelion root, sauna, and collagen.

The user is concerned about losing over 100 hairs in the shower and wonders if it's normal due to not brushing daily, stress, surgery, and PRP treatments. They are using minoxidil, spironolactone, iron, vitamin D, a multivitamin, pumpkin seed oil, and saw palmetto.

The conversation is about someone's improvement in hair density and hairline appearance after consistently using finasteride, topical minoxidil, dermarolling, and ketoconazole. They shared a progress picture showing the best results they've seen since starting treatment.

The conversation discusses using finasteride topically for hair loss and concerns about potential side effects like feminization and impact on muscle growth. One person shared their experience with finasteride, indicating it increased testosterone and did not prevent them from gaining muscle or strength.

The post discusses a user's struggle with hair loss and the ineffectiveness of finasteride. Suggestions from the conversation include trying oral minoxidil and considering a 3200 graft hair transplant.

A user experiencing significant hair loss found they had a severe vitamin D deficiency and was prescribed 50,000IU vitamin D pills, likely to be taken weekly. They are questioning if the deficiency could be the cause of their hair loss and if correcting it could stop the shedding and improve hair recovery.

The conversation is about scalp massages for hair loss, with skepticism from users who suggest using finasteride, dutasteride, and minoxidil instead. Users report no success with scalp massages and consider it a scam.

After suffering from hair loss and Seborrheic Dermatitis for three years with no improvement from various treatments, the individual found success with COQ10 and PQQ supplements, which led to new hair growth and a healthy scalp without flare-ups. They also plan to start additional supplements recommended by a dermatologist.

A 26-year-old male is experiencing hair loss and is interested in Botox scalp injections as a treatment, preferring it over finasteride due to fewer hormonal impacts. He seeks recommendations for US doctors offering this treatment and feedback from those with experience.

Minoxidil users discuss skin-care routines to counteract side effects like dark circles and dull skin. Recommendations include vitamin C, potassium, collagen, retinol, nizoral shampoo, and emu oil.

Heating foam minoxidil into a liquid for easier application and quicker drying. Effectiveness remains the same as liquid minoxidil.

28-year-old struggles with aggressive hair loss since 18, used minoxidil with limited success. Tried hair systems but found them expensive, shaved head for job interviews but plans to return to hair systems.

Finasteride may have positive effects by keeping testosterone levels higher, potentially maintaining youthfulness and physical performance as one ages. It could also help with conditions related to aging like andropause and sarcopenia without increasing estradiol levels.