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GlossaryBMI1 (Bmi-1)

regulates stem cell renewal and differentiation in hair follicles

BMI1, also known as B lymphoma Mo-MLV insertion region 1 homolog, is a gene that plays a crucial role in regulating stem cell renewal and differentiation. It is part of the Polycomb group of proteins, which are involved in modifying chromatin to repress gene expression. In the context of hair biology, BMI1 is important because it helps maintain the population of hair follicle stem cells, which are essential for hair growth and regeneration.

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community 4 years; fin 1mg/day @ 4 years; minox twice daily @ 3 years; estradiol 5mg/day @ 3 months; spiro 100 mg /day @ 3 months (Wet hair because it's easy to hide issues with dry hair)

in Progress Pictures 198 upvotes 1 month ago

The user shared their 4-year hair regrowth progress using finasteride, minoxidil, estradiol, and spironolactone. They noted significant regrowth by the second year and additional benefits from estradiol and spironolactone.

community 2 year progress on fin and minox

in Progress Pictures 1149 upvotes 4 years ago

A user's 2-year experience with Minoxidil and Finasteride as a treatment for hair loss, including the costs involved and potential side effects. Other users shared their experiences and asked questions about their own use of these treatments.

community After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?

in Finasteride/Dutasteride 95 upvotes 5 months ago

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.

community 1.5 year progress update 1mg Fin and 5% minoxidil

in Progress Pictures 343 upvotes 1 year ago

A user shared a 1.5-year hair loss treatment progress using 1mg Finasteride and 5% Minoxidil, planning to switch to oral Minoxidil and considering adding RU58841. They saw gradual improvement, suspecting Finasteride as the main contributor since they might not respond to topical Minoxidil.

community 11 months of finasteride use, but side effects are becoming increasingly real

in Finasteride 25 upvotes 6 years ago

A user experienced severe sexual side effects and man boobs after 11 months of finasteride use, despite initial positive results for hair growth. They are discontinuing finasteride and caution others about potential risks, suggesting that side effects may be more common than reported.

community Been on Propecia since 1997, recently switched to Topical Finasteride.. follow for updates, or to ask any questions about 23 years on Propecia.

in Finasteride/Dutasteride 103 upvotes 3 years ago

User spent 23 years on Finasteride with side effects like weight gain and reduced libido. Switched to topical Finasteride, side effects reduced and waiting for results.

community i went to dermatologist today and from your experience with doctors and prescriptions i want to know what do you think of that and why ?

in Treatment 8 upvotes 6 months ago

A 19-year-old is using hair tonic capsules, Minoxidil 5% lotion, an unidentified hair lotion, and Nizoral shampoo for male pattern hair loss. Commenters suggest focusing on known treatments like Minoxidil and Finasteride and advise knowing the contents of the products used.

community 2 years on fin only :) EOD. No sides.

in Progress Pictures 191 upvotes 3 months ago

A user shared their 2-year progress using finasteride every other day with no side effects. Others discussed their experiences, shedding cycles, and patience with the treatment.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

in Treatment 46 upvotes 4 years ago

A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

community This shit works like magic, aka 50 days on oral min&fin

in Progress Pictures 171 upvotes 2 months ago

A user shared their successful 50-day progress using oral minoxidil and finasteride for hair loss. They plan to switch to dutasteride after six months for potentially better results.

community If you had to choose one ? Fin or min ?

in Product 99 upvotes 4 months ago

The conversation is about choosing between finasteride and minoxidil for hair loss treatment. Most users prefer finasteride, citing its effectiveness in stopping hair loss, while some mention using both for better results.

community Bryan Johnson just dropped his anti hair loss formula

in Treatment 339 upvotes 7 months ago

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

community Hair follicles do die - my „hair“ is the proof of that statement.

in Female 9 upvotes 1 year ago

The user discusses their experience with hair loss despite taking estrogen and cyproterone, and estimates needing around 3000 grafts for a feminine hairline. They are considering getting the procedure done in Turkey due to high European costs.

community 3 months just dermarolling

in Update 50 upvotes 5 years ago

A 27-year-old man with thinning hair saw improvement after stopping Rogaine and starting dermarolling with peppermint oil, experiencing less shedding and thicker hair growth. He also uses biotin caffeine shampoo, argan oil conditioner, and a mix of castor oil with peppermint oil after dermarolling.

community Study of thousands of Fin users over 20 years finds no evidence of Fin induced sexual dysfunction

in Research/Science 372 upvotes 7 months ago

The conversation is about a finding that finasteride does not significantly increase the risk of sexual dysfunction, with users sharing mixed personal experiences regarding side effects.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 57 upvotes 10 months ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Detailed 6 months update for FUE HT and 4 years of FIN-MIN journey

in Progress Pictures 193 upvotes 11 months ago

A 25-year-old who has been using minoxidil and finasteride for 4 years to treat hair loss, underwent a successful FUE hair transplant in Mumbai, India, in April 2023. The user reported positive results, including increased hair density and reduced frizziness, and plans to continue treatment for further growth.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 11 months ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Does losing your hair make you hit the gym ?

in Satire 1 year ago

How some people start going to the gym when they begin to lose their hair, as well as discussing various treatments (Finasteride, Minoxidil and Dermarolling) for hair loss.

community Got Blood Work Lab Results for hormones. Need some help analyzing hormone values for Fin

in Finasteride/Dutasteride 7 upvotes 2 years ago

The user got blood work to check hormone levels before starting Finasteride for hair loss and is seeking advice on interpreting the results. They are considering hormone levels in relation to potential side effects of Finasteride.

community No Luck Getting Rid Of The Itchy Scalp. What Now?

in Chat 10 upvotes 1 year ago

A user experienced a burning, itchy scalp and hair thinning despite trying finasteride, steroid cream, antihistamines, various shampoos, and supplements. They seek advice on relieving the itch, hoping it will improve hair health.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 18 upvotes 7 months ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.