Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

The user experienced hair loss due to defective dutasteride and is now using a regimen including dutasteride, oral and topical minoxidil, RU58841, tretinoin, and microneedling to recover hair density. They are optimistic about regaining their hair despite recent setbacks.

The conversation is about hair regrowth using topical minoxidil, microneedling, and vitamin supplements. The user is hesitant to use DHT blockers like finasteride due to concerns about hormonal side effects.

The user is using RU58841, Minoxidil, and weekly microneedling for hair loss, having stopped finasteride due to side effects like low libido and depression. They are considering dutasteride as an alternative but are cautious due to past experiences with DHT blockers.

The user shared their hair growth journey using minoxidil, finasteride, and ketoconazole shampoo, along with vitamins and serums, reporting significant progress in five months. They emphasized the importance of stress management and plan to add a derma roller, castor oil, and a high-protein diet.

Hot weather can increase hair shedding, possibly due to dehydration and active sebaceous glands. Using shampoos with salicylic acid or zinc pyrithione may help; daily anti-inflammatory use is not recommended.

The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

Finasteride improved hair density and changed hair texture from wavy to curly for the user. The user took 1mg of oral finasteride daily without using minoxidil.

Spearmint tea and inositol are discussed as potential treatments for hair regrowth, but their effectiveness is questioned. Alternatives like green tea, MSM, and evening primrose oil are suggested for hair health.

Spironolactone and finasteride are not recommended for women planning pregnancy due to birth defect risks. Both need to be stopped months before conception, and finasteride is generally not advised for women.

A user shared their positive experience using finasteride and minoxidil at 36, after having unpleasant side effects at 18. They report no current side effects and are seeing good progress with their hair, including using microneedling weekly.

A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

The user is using biotin, pumpkin seed oil, saw palmetto, green tea, Minoxidil, Nizoral shampoo, and derma rolling to combat hair loss but is hesitant to use finasteride due to potential side effects. Others suggest that without finasteride or dutasteride, the natural approach is unlikely to be effective long-term.

Finasteride reduces scalp DHT significantly even at low doses, with 0.2 mg reducing it by about 55%, but higher doses like 1 mg and 5 mg offer only marginally more reduction. Users discuss side effects, with some experiencing none and others reporting issues like low libido, and they also mention using other treatments like minoxidil and dutasteride.

Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

The user shared their 11-month hair loss treatment experience using Dutasteride daily and Minoxidil initially, noting improvements in hair density and texture. They stopped Minoxidil in February, observed no significant shedding, and plan to continue with Dutasteride, considering reintroducing Minoxidil for more regrowth.

The user reported significant hair density improvement after 35 days using finasteride (1.25 mg) and 5% minoxidil. Some users are skeptical, while others believe the progress is genuine.

Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

Topical finasteride can be as effective as oral finasteride for hair regrowth with fewer systemic side effects, but precise dosing is essential. Combining oral dutasteride with topical finasteride is not recommended due to dutasteride's stronger inhibition.

Dutasteride is more effective than finasteride for hair loss as it blocks more of the enzyme causing hair loss. New treatments like stem cell therapies and alternatives to minoxidil are being explored, but major advancements are still years away.

GT20029 and pyrilutamide are both androgen antagonists but work differently; GT20029 degrades the androgen receptor, while pyrilutamide blocks DHT from binding. GT20029 is expected to have similar efficacy to CosmeRNA.

Topical androgen receptor antagonists may not be necessary if 5-AR inhibitors like finasteride or dutasteride effectively reduce DHT levels. Combining a 5-AR inhibitor with a topical androgen antagonist could potentially enhance treatment, but oral use of androgen antagonists is too risky due to severe side effects.

Starting finasteride earlier is generally more effective for hair loss, with no evidence of reduced effectiveness over time. Oral finasteride is recommended for better results, and starting treatment after age 18 is advised.

Use finasteride, minoxidil, and dutasteride for hair loss, with micro-needling as an additional option. Consider a hair transplant if unsatisfied, and avoid unproven treatments like RU58841.

Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

Using minoxidil 5% once a day for hair loss, with suggestions to add finasteride for better results. It also discusses the effectiveness and side effects of finasteride and the importance of consistent application.

The conversation discusses the potential of developing a selective oral SARM to target androgen activity in the scalp and skin, as an alternative to oral Dutasteride and Finasteride, which have systemic side effects. It also mentions Clascoterone and RU58841 as topical treatments for hair loss.

People are humorously discussing unconventional and satirical uses of minoxidil, such as drinking it or injecting it, and the potential absurd consequences. The conversation also touches on the ineffectiveness and risks of these methods compared to proper topical application with microneedling.

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

There are no updates on GT20029, and concerns about its safety and effectiveness remain. The phase III trial has not started, and there are no new studies or data releases.