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      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

       245 upvotes 2 years ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community Minoxidil 5% with 0.01% tretinoin

      in Treatment  1 upvotes 1 year ago
      Minoxidil 5% combined with 0.01% tretinoin may be as effective as using minoxidil twice daily. Users discuss switching to oral minoxidil for consistency, with concerns about side effects.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  10 upvotes 1 year ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community Anyone knows if koshine kx-826 has propylene glicol?

      11 months ago
      Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propylene glycol. Users report irritation with some versions of KX-826.

      community Combining Ru58841 with my Topical Formula

       3 upvotes 1 year ago
      A user is combining RU58841 with a topical formula containing finasteride, dutasteride, minoxidil, triamcinolone, caffeine, and other ingredients. They have just started using it and report no side effects so far.

      community I am doing an experience with RU58841

      in Treatment 11 months ago
      The conversation discusses a user experimenting with RU58841 for hair regrowth by ingesting it, which others find concerning. There are mentions of potential side effects and comparisons to other treatments like minoxidil, finasteride, and flutamide.

      community Why isn't anybody on topical bicalutamide?

       4 upvotes 2 years ago
      Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

      community If ru58841 didn't work for me could KX-826 help?

       4 upvotes 1 year ago
      RU58841 was ineffective for OP, who is considering adding KX-826 with finasteride. User8 suggests KX-826 may help when combined with minoxidil and dutasteride.

      community Anyone who used RU58841 without fin/dut?

      in Product  1 upvotes 1 year ago
      RU58841 was used by some for hair loss, but concerns about side effects like gynecomastia and safety were raised. Alternatives like finasteride, minoxidil, pyrilutamide, and alfatradiol were discussed, with some users reporting better experiences with these treatments.

      community Serioxyl / Stemoxydine no longer available

       4 upvotes 3 years ago
      Stemoxydine is no longer available on Amazon in the US, and users discuss alternatives for making topical finasteride. OP cannot use minoxidil due to side effects and seeks other solutions.

      community How long does a pre-mixed RU solution remain good for?

       3 upvotes 1 year ago
      RU58841 solution may lose efficacy after 12 months, and the stability of pre-mixed solutions is uncertain. The user is considering switching suppliers due to concerns about product quality.

      community August - Now with 1.25mg of fin and 1.25 mg min

      in Progress Pictures  132 upvotes 7 months ago
      The user started using 1.25 mg of finasteride and 1.25 mg of oral minoxidil, noticing some hair regrowth and thickening. They plan to continue the treatment for a year, with others suggesting patience and possibly adding topical treatments.

      community spironolactone pills to topical

      in Research/Science  6 upvotes 1 year ago
      Crushing spironolactone pills and combining them with minoxidil for topical application may be effective for hair loss, with the addition of finasteride suggested. Adding rosemary and peppermint oils can help mask the unpleasant smell.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 7 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Bicalutamide and muscles growth

       7 upvotes 1 year ago
      A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

      community GHK-Cu is reducing my Seb Derm Flare

       5 upvotes 2 months ago
      GHK-Cu helped control Seborrheic Dermatitis and reduced scalp irritation, with no immediate change in hair fall or growth. Users reported reduced flakes and healthier skin using GHK-Cu topically.

      community Low dose finestaride 6 month progress (0,25mg)

      in Progress Pictures  5 upvotes 5 months ago
      The user shared their 6-month progress using 0.25 mg finasteride, topical minoxidil, and dermastamping, noting good results but experiencing increased sleepiness. Another user suggested minoxidil might be causing the sleepiness, and the original poster considered adjusting their treatment.

      community Breezula Phase 3 confusion - did they change something?

       8 upvotes 7 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

      community 1mg fin Feb 2025-August 2025 before and after

       8 upvotes 1 year ago
      The user experienced hair improvement using 1mg finasteride daily for six months, managing seborrheic dermatitis with rosemary and eucalyptus oil. They are considering switching to dutasteride for potentially better results.

      community Making my own topical finasteride - ethanol question

       4 upvotes 3 years ago
      The conversation is about making topical finasteride using ethanol. The user is advised to use non-denatured or food-grade ethanol, as denatured ethanol may be harmful with prolonged skin exposure.

      community Breezula Phase 3 Results enough for maintenance?

       13 upvotes 4 months ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community 1.25 mg of both loniten and finasteride since 9/18/25

       6 upvotes 5 months ago
      The user has been using 1.25 mg of oral minoxidil and finasteride since September 2025 to address diffuse hair thinning, and is considering trying a new shampoo. Other users suggest increasing the minoxidil dose and trying dutasteride.

      community Is this too much powder not dissolving (DIY topical finasteride

       2 upvotes 1 month ago
      The conversation discusses DIY topical finasteride, with users sharing experiences and advice on dissolving crushed pills in a solvent. Some recommend using raw finasteride powder or buying pre-made solutions for better stability and effectiveness.

      community Fuck it. Drinking minoxidil solution

       22 upvotes 4 months ago
      A user decided to drink minoxidil solution due to difficulties with topical application and cost, taking 0.28ml daily. Others shared their experiences with similar methods, noting effectiveness and minimal side effects, while some expressed concerns about safety and self-medication.

      community Minokem-N cotains hydrocortisone?

       2 upvotes 1 year ago
      Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.