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      community Potassium and oral min need each other??

       5 upvotes 1 year ago
      Oral minoxidil may require potassium for effectiveness, and diuretics taken for water retention might affect this process. The user plans to start taking potassium to address potential issues with minoxidil's effectiveness.

      community SUBE3 for sale in the gray market?

       5 upvotes 1 year ago
      SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

      community Opinion on the recent clascoterone breakthrough?

      in Treatment  3 upvotes 8 months ago
      Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.

      community Epidemic of brand names working wildly different, if at all.

       5 upvotes 7 years ago
      The conversation discusses the variability in effectiveness of medications, including finasteride, and questions whether different manufacturers impact results. The user suggests sharing successful brands to help others identify effective options.

      community What’s the highest minox % you home brewed ?

      in Minoxidil  2 upvotes 2 years ago
      A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

      community Can absorption be intervened by oil, sebum etc?

      in Treatment  3 upvotes 2 years ago
      The conversation discusses whether oily scalp and sebum can hinder the absorption of topical hair loss treatments like Minoxidil and Finasteride, even when using tretinoin. The user is skeptical about the effectiveness of these treatments due to their oily scalp condition.

      community Pp405 full presentation on new topical

       106 upvotes 5 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community 25yo. 4 months progress of 0.5 Dut, 2.5mg min and 10mg Biotin oral.

       62 upvotes 5 months ago
      A 25-year-old shares 4 months of hair loss progress using 0.5mg Dutasteride, 2.5mg Minoxidil, and 10mg Biotin in one capsule. They experienced significant improvement by month 2, despite a big shed at month 3, with no side effects reported.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community 0.2 dut or 0.5? does it matter

       1 upvotes 1 month ago
      The conversation discusses using a daily pill containing 0.2mg dutasteride and 2.5mg oral minoxidil for hair loss, with considerations about increasing the dutasteride dose to 0.5mg. Users also mention the benefits of taking these medications daily and the potential cost savings of getting prescriptions directly.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community Update for PP405 - phase 2b underway

       122 upvotes 1 year ago
      PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

      community Making topical finasteride (without minox)

       5 upvotes 4 years ago
      A user is exploring making a low-dose topical finasteride solution without minoxidil, using stemoxydine as a vehicle. Others suggest buying from a supplier instead of making it themselves.

      community KX-826 , a small change in the pipeline

      in Research/Science  6 upvotes 7 months ago
      KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

      community ABS-201 Trial - What should I know going in

      in Research/Science  28 upvotes 6 months ago
      The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.

      community 500mg pill of dutesteride ? Will I become Jesus him self ?

      in Satire  53 upvotes 1 year ago
      The conversation humorously discusses the exaggerated effects of taking a 500mg pill of dutasteride, with users joking about extreme side effects like excessive hair growth and loss of sensation. It also mentions personal experiences with finasteride and the potential high bioavailability of dutasteride in liquid form.

      community My turn to come out and show. I think it might be improving.

       422 upvotes 9 months ago
      The user experienced increased hair density after starting 1mg finasteride in February and 2.5mg oral minoxidil two months ago, along with 10mg biotin daily. They initially used topical minoxidil but switched to oral due to application difficulties and have seen improvements without significant side effects.

      community Finasteride and male phenotypes

       5 upvotes 11 years ago
      Finasteride's effectiveness and side effects may vary based on male phenotypes, with some users noting differences in response related to body and facial hair characteristics. Some users report success with lower doses, while others experience side effects, suggesting individual variability in response to the treatment.

      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

       18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community which is better ; minoxidil with more alcohol or more pg?

       4 upvotes 4 years ago
      The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.

      community I ingested RU58841 orally to see if its legit

       131 upvotes 1 year ago
      A user ingested RU58841 orally and experienced severe heart and breathing issues, requiring emergency medical assistance. They concluded that MV supplements is a legitimate supplier but warned of the serious side effects.

      community How come i see lower dose fin, when 1mg is recommended

      in Treatment  6 upvotes 4 months ago
      People are using lower doses of finasteride than the recommended 1mg daily due to concerns about side effects, cost, and new data suggesting lower doses can be nearly as effective. Some users report stability or slight improvements with lower doses, but the effectiveness compared to 1mg daily is debated.

      community Kintor long term safety phase 3

      in Research/Science  66 upvotes 1 year ago
      Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.