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      community Pelage Announces Positive Results of Phase 2a Trials for PP405

       303 upvotes 1 year ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community is there any news about pp405 please

       10 upvotes 1 year ago
      There is no new information on pp405, with data collection expected to finish by the end of 2025. Users are discussing the timeline for data analysis and completion of Pelage Pharmaceuticals' phase 2 study.

      community MicroRNA science breakthrough? Softening stem cells

       6 upvotes 3 years ago
      A potential breakthrough in hair loss treatment involves softening hair follicle stem cells, but its effectiveness in humans is uncertain. Users express skepticism, noting past successes in mice that haven't translated to human treatments.

      community Anyone used peptides from bulknaturals?

       1 upvotes 1 year ago
      The conversation discusses using GHK-Cu copper peptide from Bulk Naturals for hair loss, comparing its price and quality to Peptide Sciences. Concerns about the product's legitimacy are mentioned, but COA documents are available.

      community Who is the ideal target for PP405? Will it render hair trasplants obsolete?

       2 upvotes 5 months ago
      PP405 is being discussed as a potential treatment for hair loss, with uncertainty about its effectiveness compared to existing treatments like finasteride, dutasteride, and minoxidil. There is cautious optimism, but its impact on hair transplants remains unclear.

      community 2.5 months of topical Finasteride

      in Progress Pictures  272 upvotes 10 months ago
      A user reported significant hair regrowth using a homemade 0.01% topical finasteride solution, highlighting its effectiveness and lack of side effects. The discussion included concerns about oral finasteride's side effects and the benefits of topical solutions.

      community Update for PP405 - phase 2b underway

       122 upvotes 1 year ago
      PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

      community Whatever happened to breezula?

      in Finasteride/Dutasteride  16 upvotes 1 year ago
      Breezula, a potential hair loss treatment, is still in trials with no recent updates on its release, while its acne version, Winlevi, is available but expensive. Users discuss the high cost of hair loss treatments and alternatives like Minoxidil and topical Finasteride.

      community Thoughts of this sub on Melatonin?

       3 upvotes 1 year ago
      Melatonin, gingko biloba, and biotin are effective for treating hair loss with good tolerability. Alternatives like dutasteride, minoxidil, and other peptides are also discussed.

      community Getting PP405. Now…. or as soon as possible

       147 upvotes 1 year ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

      community I cant believe its actually working…

       27 upvotes 10 months ago
      The user experienced significant hair regrowth using 1mg oral finasteride, DIM, and beetroot powder, while also focusing on gut health and reducing alcohol intake. Other users discussed the importance of iodine, fermented foods, and maintaining a balanced diet for overall health and hair improvement.

      community How much do we know about PTD-DBM?

       7 upvotes 8 years ago
      PTD-DBM is a Korean-developed treatment for hair loss, with limited information available and some users testing it personally. A user purchased PTD-DBM for $115 and plans to test it on their temples, but its effectiveness and authenticity remain uncertain.

      community Keratin microspheres - breakthrough

       14 upvotes 2 years ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

       245 upvotes 2 years ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community [PSA] - Do NOT swallow dutasteride capsule content.

       43 upvotes 9 months ago
      Dutasteride capsules should not be bitten or opened due to their foul taste and potential caustic effects. Users shared experiences of accidentally biting capsules and the unpleasant taste, with some suggesting swallowing techniques to avoid this.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 1 year ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Using a 2-deoxy-d-ribose gel. My experience 2 weeks in.

      in Treatment  38 upvotes 1 year ago
      The user switched from minoxidil to a homemade 2-deoxy-d-ribose gel and noticed no hair fall after two weeks, despite stopping minoxidil. The gel includes water, 2-deoxy-d-ribose, vegetable glycerine, 2-phenoxyethanol, sodium alginate, and rosemary oil, and the user reports healthier-feeling hair.

      community Experience with CB (Breezula)?

       4 upvotes 6 years ago
      CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

      community Plant-based Exosomes Efficacy Sourced from South Korea

       2 upvotes 1 year ago
      Plant-based exosomes for hair loss lack scientific evidence and are considered high-risk with low evidence. Combining PRF with minoxidil and finasteride is suggested as a better option.

      community Today was Last update on pp405

       109 upvotes 1 year ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.