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    Glossaryβ-catenin

    protein involved in cell signaling and hair follicle regulation

    β-catenin is a protein that plays a crucial role in cell signaling and the regulation of cell growth and development. It is a key component of the Wnt signaling pathway, which is important for processes like embryonic development and the maintenance of adult tissues, including hair follicles. Abnormal β-catenin activity is associated with various conditions, including cancer and hair loss disorders like alopecia.

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      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  8 upvotes 3 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community (Topic) does saw palmetto actually work?

      in Chat  1 upvotes 1 month ago
      Saw palmetto can help reduce DHT levels and may work in combination with other supplements like beta sitosterol and pygume, but it's less effective than finasteride. Additional treatments like pumpkin seed extract, zinc, biotin, essential oils, scalp massages, and micro-needling can support hair health, but should not replace existing treatments like finasteride.

      community 5-month finasteride - diffuse thinning update

      in Progress Pictures  13 upvotes 2 weeks ago
      The user shared a 5-month update on using finasteride, minoxidil, and ketoconazole shampoo for diffuse thinning, along with supplements like B-Vitamins, D-Vitamins, Iron, and Beta carotene. They noted improvement in hair condition and encouraged others to check previous posts for more information.

      community The ultimate Regimen for density and thick ess

      in Treatment  10 upvotes 1 month ago
      The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hair growth and density, with considerations for potential skin irritation and interactions between treatments.

      community progression 1 month male 22 balding

      in Progress Pictures  8 upvotes 1 year ago
      A 22-year-old male using finasteride, minoxidil, and derma stamping for one month reports progress in hair loss treatment. He also uses vitamin D, omega-3, beta carotene, tongkat ali, and ag powder, and maintains an active lifestyle.

      community A battle won?

       6 upvotes 9 years ago
      The user tried various treatments for hair loss, including finasteride, vitamins, Saw Palmetto, beta sitosterol, pumpkin oil, borage oil, stinging nettle, and emu oil. They recently noticed tiny black hairs, suggesting some improvement.

      community My Experience and a Discourse on "DUPA"

      in Treatment  9 upvotes 6 months ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

      community Fighting Hair Loss without Finasteride?

       8 upvotes 9 years ago
      A user discusses fighting hair loss without finasteride, using minoxidil, ketoconazole shampoo, saw palmetto, pumpkin seed oil, pygeum, stinging nettles, biotin, a boar bristle brush, and a derma roller. Replies suggest finasteride is necessary for effective hair loss prevention.

      community What else is good. Besides the big 3.

      in Chat  36 upvotes 1 month ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

      in Research/Science  39 upvotes 4 months ago
      David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

      community Taurine supplements work for hair growth?

      in Product  8 upvotes 7 months ago
      The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

      community Topical Saw Palmetto: An Alternative to Microdosing Topical Finasteride?

      in Product  16 upvotes 1 year ago
      The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.

      community The Oral Minoxidil hype, use your head .

      in Minoxidil  10 upvotes 2 years ago
      The conversation is about the risks and uncertainties of using oral Minoxidil for hair loss, emphasizing that topical Minoxidil may be just as effective. It also mentions alternative treatments like micro-needling and retinol.

      community 6 month progress. Fin/Min daily.

      in Progress Pictures  506 upvotes 4 years ago
      A user's 6 month progress using finasteride and minoxidil as treatments for hair loss, with the replies discussing side effects and general consensus about usage of the two medications.

      community Creating the Holy Grail Hair Loss Topical

       1 upvotes 4 years ago
      The conversation is about creating a natural hair loss topical using ingredients like cetirizine, Zinc Sulphate Heptahydrate, Safflower Extract, Ricinoleic Acid, and others. The user is seeking input and collaboration on this topical formula.

      community I try without Fin. 6 month (1 year experience).

      in Is this regrowth?  17 upvotes 1 month ago
      The conversation discusses hair loss treatments, with the original poster using saw palmetto, biotin, minoxidil, a dermaroller, and rosemary oil, considering finasteride or a hair transplant in the future. Other users suggest finasteride or dutasteride for more effective results, while some recommend additional natural supplements and maintaining overall health.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  162 upvotes 2 months ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.
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