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      community 3 months progress!! Fin + Min + Derma roller + Nizoral Shampoo.

      in Progress Pictures  562 upvotes 1 year ago
      The post discusses a user's successful hair regrowth after 3 months using 1 mg oral finasteride, oral minoxidil, weekly 1.5mm derma rolling, and Nizoral shampoo every other day, with no side effects. The conversation includes various responses, questions about the user's ethnicity and previous scalp condition, and suggestions for topical treatments.

      community Topical Pyrilutamide - Hormone Panel

      in Treatment  2 upvotes 1 year ago
      The user used 0.5 mL of 0.5 mg of Pyrilutamide for 60 days for hair loss, but didn't notice any hair growth. They shared their hormone panel results and are seeking advice on next steps.

      community All Drugs in Clinical Trials in 2023

      in Research/Science  69 upvotes 1 year ago
      12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

      community Kintor’s GT20029 Phase 1 success

      in Update  74 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community How to Keep Your Hair on Steroids

      in Treatment  14 upvotes 3 weeks ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

      community Finasteride + Cialis together long term?

      in Treatment  3 upvotes 1 month ago
      The user has been on 1mg finasteride for a year, experiencing low libido and moderate erectile issues. They are considering using Cialis daily with finasteride long term to address these side effects.

      community To everyone who cant use FIN and doesnt want to use RU

      in Treatment  33 upvotes 1 month ago
      A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.

      community 16M topical min Kirkland 5% 2*1 ml ED, saved from dead

      in Progress Pictures  45 upvotes 1 month ago
      A user shared their hair loss journey, detailing their use of Kirkland Minoxidil 5%, finasteride, dutasteride, and weekly dermarolling. They experienced initial success with minoxidil but faced setbacks with oral minoxidil and are now back on topical treatments.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  372 upvotes 1 month ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Can Fin + Min save my hair? [20M]

      in Satire  3059 upvotes 2 months ago
      A user is considering using finasteride and minoxidil to address hair loss, particularly at the temples and crown. Responses include encouragement, humor, and additional suggestions like using a derma roller.

      community MY Hair Loss Treatment Summary

      in Treatment  7 upvotes 4 months ago
      The conversation is about various hair loss treatments, including finasteride, minoxidil, RU58841, and natural supplements like saw palmetto and pumpkin seed oil. It also covers methods to improve blood circulation, nourish hair follicles, and address underlying health issues like vitamin D deficiency and high cortisol levels.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 4 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Why are there no FDA approved NSAA's yet?

      in Research/Science 4 months ago
      The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community Ketoconazole mesotherapy plausible?

      in Ketoconazole  8 upvotes 4 months ago
      The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

      community Thoughts on my Topical and Oral concept idea ?

      in Treatment  1 upvotes 5 months ago
      The user is seeking advice on improving their hair loss treatment regimen, considering changes to their topical solution, and is curious about others' daily routines and recommendations for medications and supplements. They are contemplating switching Tretinoin for Tazarotene, Latanoprost for Bimatoprost, and possibly adding Alfatradiol, Topical Melatonin, or a topical androgen receptor antagonist.

      community Chances of GT20029 hitting the black market?

      in Treatment  11 upvotes 5 months ago
      The conversation is about the potential availability of GT20029 on the black market and whether users would try it. Participants advise waiting for phase 3 trial results to ensure safety and efficacy.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 5 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 7 months ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.