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GlossaryAntinuclear Antibody

autoantibodies targeting cell nuclei, often indicating autoimmune diseases

Antinuclear Antibody (ANA) refers to a type of autoantibody that targets substances found in the nucleus of cells. These antibodies are often present in individuals with autoimmune diseases, such as lupus or rheumatoid arthritis, and their presence can be detected through a blood test to help diagnose these conditions.

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community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 2 months ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community Well ladies and gents here is the 3 month mark! Not as crazy as some I’ve seen here but I’m pretty pleased so far! Fin,min,ru,keto, needling 🤘🏻

in Progress Pictures 669 upvotes 2 years ago

User shared 3-month progress of hair regrowth using Fin, Min, RU, keto, and needling. Others praised results and asked for routine details.

community My nuclear protocol (scary but very effective)

in Treatment 80 upvotes 2 years ago

A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.

community 4 month update - nuclear stack, 42m

in Progress Pictures 254 upvotes 3 months ago

A 42-year-old user shared a 4-month update on their hair regrowth using a "nuclear stack" including oral and topical minoxidil, dutasteride, RU58841, micro-needling, keto shampoo, saw palmetto, biotin, multivitamins, scalp massages, and inversion table. They reported significant progress with minimal side effects and plan to continue the routine.

community I'm on multiple anti-androgens and after around year, my hairs are thinner, why?

in Finasteride/Dutasteride 16 upvotes 1 year ago

The user has been using finasteride, dutasteride, pyrithione zinc, and oral minoxidil to treat hair loss and has seen an increase in fine hairs on the hairline but overall thinning on the top. They are considering adding zinc and Vitamin K to their regimen and are already taking hair multivitamins with collagen.

community 3 Month Results with Nuclear Stack - 42M

in Progress Pictures 116 upvotes 4 months ago

A user shared 3-month hair regrowth results using a combination of oral Dutasteride, daily Minoxidil, RU58841, micro-needling, Keto shampoo, scalp massages, and supplements. Positive progress was noted, and encouragement to continue was given.

community If RU58841 is such an effective anti androgen

in Research/Science 46 upvotes 11 months ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

community My Last Post on this Subreddit: Nuclear Option

in Chat 27 upvotes 1 year ago

User starts final hair loss regimen with various treatments and plans to leave subreddit for mental health. Others believe user's hair is fine and the regimen is unnecessary and potentially harmful.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Why do some have no change even on nuclear stacks ?

in Research/Science 16 upvotes 10 months ago

Some people see significant hair regrowth using treatments like finasteride and minoxidil, while others experience little to no improvement even with comprehensive treatment plans. Factors such as individual sensitivity to DHT may influence the effectiveness of these hair loss treatments.

community Questions about dutasteride, minoxidil and nuclear option?

in Minoxidil 6 upvotes 2 years ago

The user discussed their experience with hair loss treatments, including finasteride, RU58841, Nizoral, supplements, dermarolling, and minoxidil, which caused significant edema. They also experimented with dutasteride, which led to increased hair loss, and found that Armodafinil reduced minoxidil-related water retention and hair shedding.

community Any current RU58841 user experiences? I just added it to my nuclear stack.

in Treatment 10 upvotes 1 year ago

A 26-year-old individual treating hair loss since 19, using a regimen of Finasteride, Cyproterone, Oral Minoxidil, Microneedling, Dutasteride, and newly added RU58841. They're seeking advice from other RU58841 users about their experiences.

community How to Keep Your Hair on Steroids

in Treatment 19 upvotes 3 months ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 1 year ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community 11 Months Pantostin / 3 Months 25mg CPA

in Is this regrowth? 15 upvotes 1 year ago

The user is asking for opinions on whether their hair growth is due to Pantostin and hormone treatments. One commenter confirms regrowth and asks about the hormone treatments.

community Almost 90 days. The hair gods taketh and now giveth.

in Progress Pictures 721 upvotes 1 year ago

User "mynameisbogus" shares hair regrowth progress after 90 days using Dutasteride, oral and topical Minoxidil, RU58841, dermarolling, and Keto shampoo. Others in the conversation praise the impressive results and discuss their own experiences with hair loss treatments.

community Is the Ru58841 hype justified?

in Treatment 17 upvotes 2 months ago

RU58841 is debated for hair regrowth, with some users reporting no benefits and potential side effects, while others claim success when combined with dutasteride. Many suggest safer, well-researched treatments like finasteride and minoxidil for hair loss management.

community 2 months progress. Hair is shorter in the first pic, same length in the second and third.

in Progress Pictures 294 upvotes 1 year ago

User reports 2 months progress using daily oral fin 1mg, twice daily topical min 5%, and intermittent dermapen. Others share their experiences, suggesting patience and additional treatments like alternating shampoos, using conditioner, tretinoin, and vitamins.

community 5 Month's progress on Topical FIN, MIN, Topical Dut, Laser Cap

in Progress Pictures 577 upvotes 3 years ago

User "hemantch" shares 5 months progress using topical Fin, Min, topical Dut, and a laser cap for hair loss. Significant regrowth was noticed after 1 month, and the treatments worked well despite being bald for 10 years.

community blood DHT levels shot up after doubling dutasteride dosage

in Finasteride/Dutasteride 20 upvotes 7 months ago

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

in Microneedling 1 upvotes 7 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 7 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Love me some Dutasteride. 40 years old. March to now

in Progress Pictures 753 upvotes 1 year ago

The conclusion of this conversation about hair loss is that the user, "mynameisbogus," has been using Dutasteride, oral minoxidil, topical minoxidil, RU58841, dermarolling, scalp massaging, and keto shampoo to treat their hair loss. They have not experienced any side effects and have seen positive results.

community Ultimate Stack without nuking your gender (you'll go broke)

in Treatment 79 upvotes 3 weeks ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

community After Years of Treatment, I'm Shaving my Head and Giving Up

in Shaved/buzzed 118 upvotes 1 month ago

After years of using dutasteride and oral minoxidil without success, the individual decided to shave their head and stop treatment. They considered scalp micropigmentation and hair systems but ultimately accepted their hair loss.

community Is switching to Dut after 3 months of Fin too soon?

in Chat 7 upvotes 1 month ago

Switching from finasteride to dutasteride after three months is debated, with some suggesting it's too soon to see results, while others recommend dutasteride for better regrowth. Users discuss combining treatments like minoxidil and microneedling, but opinions vary on their effectiveness.

community What is everyone's stack and why?

in Treatment 21 upvotes 2 months ago

People are using various treatments for hair loss, including dutasteride, finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. Some also use additional methods like microneedling, vitamins, and oils, with mixed results and personal preferences influencing their choices.

community No gains after 4 years of min and fin

in Progress Pictures 92 upvotes 5 months ago

User has seen no improvement after 4 years of using minoxidil and finasteride, and recently started dutasteride. Suggestions include adding oral minoxidil, microneedling, and considering a hair transplant.

community If dutesteride and oral minoxidil doesn’t work that’s it right?

in Treatment 41 upvotes 7 months ago

A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.