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Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

A user is experiencing mild hair loss and is hesitant to try finasteride due to potential side effects. They are considering using Research Verified Hair Growth, which contains various vitamins and minerals, and are seeking opinions and experiences from others.

The user has been treating their hair loss with oral Minoxidil, Dutasteride twice a week, daily head massages, a mix of essential oils, and one round of Scalp Micropigmentation (SMP). They stopped micro-needling due to hair loss, and are seeking advice on their progress, with responses suggesting continued treatment, potential hair transplant, and resuming micro-needling.

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

User shows hair loss progress from NW4 to NW2.5 in 2.5 months using RU 8.5-9% daily and topical Dut .1% + RU 5% weekly. Discussion includes managing tension in African American hair and representation of different hair types.

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

The conversation is about using Ketoconazole shampoo for hair loss, with users discussing leaving it on the scalp for longer periods. Some users report benefits for dandruff, but there's uncertainty about its effectiveness for androgenetic alopecia (AGA).

User "yungnickyyp" shares 5-month progress using Fin/Min/Niz/Derm for hair loss. Others express jealousy and amazement at the significant hair regrowth.

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.

User tried topical and oral finasteride and oral minoxidil for hair loss without success. ButterscotchSea3159 suggests using Dutasteride, oral minoxidil, ketoconazole shampoo, microneedling, and possibly RU for better results.

Whether topical caffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

User on finasteride for a decade and oral minoxidil for a month asks about Nizoral shampoo's effectiveness and usage. Dermatologist suggests it may help with seborrheic dermatitis and hair loss, but not necessary; others share mixed opinions.

Kintor Pharma completed patient enrollment for a Phase II trial in China for GT20029, a potential new treatment for hair loss. Some believe GT20029 could replace finasteride if effective, while others discuss finasteride's limited efficacy and potential underreported side effects.

A user shared their positive 3-month experience using finasteride, minoxidil, and vitamin D to treat hair loss, noting significant regrowth and minimal shedding. They also discussed potential side effects and the low likelihood of experiencing them, while being open to answering further questions.

The user has tried topical minoxidil, oral minoxidil, finasteride, RU58841, and dermapen for over a year without seeing hair regrowth and has now switched to dutasteride, planning to continue until summer. Some responses suggest that no further hair loss could be considered progress, question the visibility of hair loss, and recommend trying vitamin D.

The conversation discusses the appearance of new baby hairs with treatments like castor oil, finasteride, minoxidil, and dermarolling. Users note that baby hairs often go unreported after initial excitement, with some seeing growth and others losing interest in updates.

An 18-year-old shared a 5-month hair transformation using RU58841 and minoxidil, reporting no side effects and crediting most regrowth to minoxidil. Opinions on RU58841 are mixed, with some users and a YouTuber moving away from it due to side effects and lack of studies.

The post discusses whether finasteride can maintain hair growth stimulated by minoxidil. The response indicates that finasteride cannot sustain minoxidil-grown hairs.

Switching from finasteride to dutasteride after three months is debated, with some suggesting it's too soon to see results, while others recommend dutasteride for better regrowth. Users discuss combining treatments like minoxidil and microneedling, but opinions vary on their effectiveness.

A person mistakenly drank an entire bottle of topical minoxidil, leading to ICU admission with shock and heart failure. The incident highlights the dangers of ingesting topical treatments and the importance of proper usage and dosage.

A user shared their 7-month progress using 1mg daily Dutasteride and 2.5-5mg daily oral Minoxidil for diffuse unpatterned alopecia, showing significant hair regrowth with reduced shedding and no side effects. They experienced a severe initial shed but now have visual improvement, despite hair still being thinner than before.

User shared 5.5-month progress using 0.5mg finasteride, 5% minoxidil, 1.5mm microneedling weekly, and 20mg RU58841, with positive results and no side effects. Others discussed their experiences, dosage adjustments, and the importance of age in treatment efficacy.

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

A user's 6 month hairline results from using dutasteride and microneedling, which resulted in successful regrowth of their thinning temples. Other users commented with similar experiences that were also achieved through the use of finasteride, dutasteride and minoxidil.

The conversation discusses hair loss and treatments, with users suggesting the original poster's hair has receded despite using a dermaroller and RU58841 for two months. Many recommend starting finasteride and minoxidil for better results.