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      community Wtf have we been doing for the last 30 years

      in Treatment  525 upvotes 4 days ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

      community Starting ketoconzole. How much and How many times a week?

      in Ketoconazole  12 upvotes 1 month ago
      A user is experiencing severe dandruff and hair loss, considering using ketoconazole shampoo 2% to manage these issues. They seek advice on application frequency and effectiveness, with suggestions to use it 2-3 times a week and to consider other treatments like finasteride for hair loss.

      community What's "wrong" with oral minoxidil, exactly?

      in Minoxidil  173 upvotes 2 months ago
      Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

      community KX-826: Long-Term Safety Results are out!

      in Research/Science  156 upvotes 2 months ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

      community What’s the most effective way to beat Serb Derm?

      in Treatment  7 upvotes 3 months ago
      OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

      community Tristan Tate stopped using fin i guess???

      in Satire  468 upvotes 3 months ago
      Tristan Tate's hair loss is discussed, with mentions of finasteride, minoxidil, and dutasteride as treatments. Users speculate on his hair styling, steroid use, and legal troubles.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 4 months ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 4 months ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 4 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Received Kintor’s KX-826 Today

      in Product  84 upvotes 4 months ago
      A user received Kintor’s KX-826/Pyrilutamide and shared initial impressions, noting concerns about the product's labeling and marketing. Other users discussed the legitimacy of the product, its effectiveness, and compared it to other treatments like Minoxidil and Finasteride.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  366 upvotes 7 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 8 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Diffuse thinning fucking sucks

      in Update  430 upvotes 10 months ago
      The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.

      community I’m really tired of using minoxidil

      in Minoxidil  42 upvotes 1 year ago
      The user is frustrated with minoxidil's lack of results and is considering alternatives like oral minoxidil or finasteride despite concerns about side effects. Other suggestions include consulting a doctor, adjusting dosages, or considering a hair transplant.

      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 1 year ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community I’m just Going to let Nature take its Course

      in Chat  213 upvotes 1 year ago
      The post and conversation are about a 23-year-old deciding to stop using finasteride for hair loss due to potential erectile dysfunction risks, sparking a debate about the benefits and side effects of hair loss treatments.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  253 upvotes 1 year ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  26 upvotes 1 year ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 2 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  28 upvotes 2 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 2 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 2 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community Starting Fluridil (Eucapil) Topical

      in Update  14 upvotes 2 years ago
      AltruisticBro's experience with Fluridil (Eucapil) as a hair loss treatment, and the current blood work results associated with it. They are not willing to take finasteride due to potential permanent side effects.