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      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 1 year ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.
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      community Finasteride won’t make all your problems go away

      in Finasteride/Dutasteride  323 upvotes 1 year ago
      A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 1 year ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community where does the renewed spironolactone hype come from?

      in Research/Science  8 upvotes 2 years ago
      Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

      community Homemade Topical Finasteride Formula?

      in Treatment  7 upvotes 2 years ago
      User wants to make homemade topical finasteride to minimize side effects and asks about using glycerin, stirring time, storage, and alternative solvents. Another user's comment is unclear.
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      community Breezula by Cassiopea has had a successful Phase II. Apparenlty Phase III trials to start at the end of year. When are we potentially going to be able to get our hands on it?

      in Question  14 upvotes 5 years ago
      The conversation discusses the hair loss treatment Breezula by Cassiopea, which had a successful Phase II trial and is expected to start Phase III by the end of the year. Users are curious about the timeline for availability and note that it performs slightly better than finasteride at 6 months, slightly worse at 12 months, with the benefit of having no side effects.

      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  9 upvotes 5 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community Breezula phase 3 results said to be released next month

      in Product  25 upvotes 3 weeks ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 5 months ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 5 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Actually making progress, I think.

      in Is this regrowth?  66 upvotes 7 months ago
      User reports seeing fast hair regrowth after 1 month and 12 days using 0.3% Finasteride and 6% Minoxidil. They are considering microneedling and received advice to use a derma stamp.

      community Is there any new drug that looks promising ?

      in Research/Science  24 upvotes 10 months ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 10 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  102 upvotes 10 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Diffuse thinning fucking sucks

      in Update  430 upvotes 11 months ago
      The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.

      community Have you tried Biotin supplements for your hair?

      in Product  25 upvotes 1 year ago
      People shared that Biotin supplements did not improve their hair loss and some experienced stronger nails or more pimples. They suggested trying finasteride or minoxidil instead for hair loss treatment.