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      community Why haven’t we seen anything about this

      in Research/Science  18 upvotes 4 years ago
      A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

      community Is it ok to supplement spearmint?

      in Treatment 4 years ago
      The conversation discusses the potential effects of spearmint on acne and male pattern baldness (MPB). Concerns are raised about spearmint's androgen-suppressing effects and its suitability for men.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community How do you use rosemary oil and peppermint oil?

      in Question  6 upvotes 4 years ago
      Rosemary oil and peppermint oil may promote hair growth and increase cutaneous blood flow, showing promise as treatments for androgenetic alopecia. Minoxidil 2% is also used for treating hair loss.

      community Dramatic hairloss after stopping Minoxidil?

      in Minoxidil  8 upvotes 4 years ago
      User pancake9001 experienced minimal hair growth with Minoxidil for 3 years, but noticed dramatic hair loss after stopping. Replies suggest not stopping Minoxidil and considering adding an anti-androgen for better results.

      community Upcoming Setipiprant clinical trials hint at systemic daily dosage

       21 upvotes 8 years ago
      The conversation discusses the safety, tolerability, and efficacy of oral Setipiprant tablets for treating androgenetic alopecia compared to finasteride. It mentions the high cost of Setipiprant on the black market and the trial's end date in September 2017.

      community *WOMEN* on Spironolactone - experiences?

       6 upvotes 9 years ago
      Hair loss treatments discussed: Minoxidil, Finasteride, RU58841, and Spironolactone. Woman with androgenetic alopecia and alopecia areata shares experience using Spironolactone.

      community Started war against AGA, who’s gonna win ?

      in Minoxidil  125 upvotes 1 week ago
      The conversation discusses various treatments for hair loss, including minoxidil, finasteride, and topical dutasteride, with users debating their effectiveness and side effects. Despite the treatments, many believe androgenetic alopecia (AGA) ultimately prevails in the long term.

      community Im shedding more short hairs??

      in Is this regrowth?  1 upvotes 3 months ago
      A 16-year-old experiencing hair thinning noticed a shift from shedding long hairs to shorter hairs, while using Vitamin D, biotin supplements, ketoconazole shampoo, and improving diet. They are questioning if the short hairs indicate regrowth or androgenetic alopecia (AGA).
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Thoughts on my Topical and Oral concept idea ?

      in Treatment  1 upvotes 7 months ago
      The user is seeking advice on improving their hair loss treatment regimen, considering changes to their topical solution, and is curious about others' daily routines and recommendations for medications and supplements. They are contemplating switching Tretinoin for Tazarotene, Latanoprost for Bimatoprost, and possibly adding Alfatradiol, Topical Melatonin, or a topical androgen receptor antagonist.

      community About a month of progress, weirdly better than expected?

      in Progress Pictures  6 upvotes 7 months ago
      The user reported unexpected hair growth on their crown after using a derma stamp, ketoconazole, and other treatments like rosemary oil and biotin, but before starting finasteride or minoxidil. They questioned if the growth was due to these treatments or an underlying issue besides androgenetic alopecia.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  6 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community I feel like people here shrug off nutritional issues too quickly. Particularly for Retrograde Alopecia.

      in Chat  9 upvotes 1 year ago
      The user believes Retrograde Alopecia may be linked to vitamin imbalances, specifically from taking too much Vitamin E, A, Zinc, and Selenium, and suggests it could be a middle ground between Androgenic Alopecia and Telogen Effluvium. Treatments for hair loss mentioned include Androgen inhibitors and improving lifestyle factors like nutrition and sleep, with topical melatonin also recommended for Retrograde Alopecia.

      community Brutal Hair loss At 19: Help+Treatment Questions

      in Chat  6 upvotes 3 years ago
      A 19-year-old experiencing hair loss since 17 uses finasteride, minoxidil, dermaroller, ketoconazole shampoo, and oral castor oil, but sees little improvement. They seek advice on adding an anti-androgen, considering alfatradiol.

      community 6 months update. Have I made some progress?

      in Is this regrowth?  13 upvotes 3 months ago
      A user shared their 6-month hair loss treatment regimen, including Minoxidil, finasteride, microneedling, and keto shampoo, and asked for feedback on their progress. They are seeking opinions on whether their hair has regrown.

      community shampoo nizoral 1% information

      in Ketoconazole  3 upvotes 1 year ago
      User has itching, dandruff, and scalp issues, considering Nizoral 1% shampoo for treatment. Nizoral's effectiveness for hair loss is uncertain due to limited research, short contact time, and concentration differences.

      community Olumiant active ingredient Baricitinib

      in Research/Science  1 upvotes 1 year ago
      The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

      community Zero progress and hair slightly getting worse

      in Chat  7 upvotes 2 months ago
      A 21-year-old has been using 1 mg of finasteride and 1 mg of oral minoxidil for 10 months with no progress and worsening hair. They are considering switching to dutasteride and are seeking success stories and advice.

      community It's probably RU58841, which is weak in adenosine.

      in Treatment  16 upvotes 4 months ago
      The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.

      community Is fluridil cost-efficiency absolute garbage?

      in Product  1 upvotes 7 months ago
      Fluridil is considered safe with moderate effectiveness for hair loss, but its cost of €50 per month is seen as high compared to other treatments. The user is considering Pyri as a more cost-effective option and is seeking success stories about Fluridil's ability to stop hair loss without side effects.

      community 1 Year Estradiol HRT, Oral Finasteride, Bicalutamide, Cyproterone. (20MTF)

      in Transgender  4 upvotes 1 year ago
      The conversation discusses a 20-year-old transgender female's one-year experience with hair loss treatments, including Estradiol HRT, oral Finasteride, Bicalutamide, and Cyproterone. Specific treatments used for hair loss are oral Finasteride and potentially Estradiol as part of hormone replacement therapy.

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 2 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

      community Lost 65% of hair last 3 years. No regrowth. Also have Seborrheic Dermatitis flare ups. Diagnosed by derm as "alopecia". Started taking 2 supplements I researched and 0 flare up for over 2 months. New hair growing. Scalp healthy. Everything else has stayed the same! Overjoyed is an understatement!!

      in Treatment  19 upvotes 1 year ago
      After suffering from hair loss and Seborrheic Dermatitis for three years with no improvement from various treatments, the individual found success with COQ10 and PQQ supplements, which led to new hair growth and a healthy scalp without flare-ups. They also plan to start additional supplements recommended by a dermatologist.

      community What happened to Breezula ????

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the effectiveness of a hair loss treatment called CB (Breezula) in comparison to Pyrilutamide, and its potential when combined with Finasteride. There is uncertainty about when or if phase 3 trials for Breezula will begin.