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      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 11 months ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community C’est terrible - at my wits end

      in Female  444 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Hair much worse after 6 months?

      in Progress Pictures  230 upvotes 1 year ago
      A user experienced significant hair loss after 6 months of using 0.5mg finasteride daily. Suggestions from others included trying Dutasteride and Minoxidil, getting professional help from a dermatologist, and addressing high iron levels that could be contributing to the hair loss.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community How insane is this oral min shed?

      in Progress Pictures  111 upvotes 1 year ago
      A user started taking 0.625mg oral minoxidil daily for hair loss, increased the dose to 1.25mg, and experienced a significant shed, losing 70% of scalp density. They cannot tolerate finasteride due to side effects but are hopeful for hair regrowth despite the shedding.

      community Sweet Lord my DHT itch is finally gone

      in Chat  49 upvotes 1 year ago
      Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 1 year ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community My hairloss stack, progress pics soon maybe for 1 year RU

      in Technology  49 upvotes 1 year ago
      The conversation is about a user's hair loss treatment routine, which includes RU58841 for 9 months and Dutasteride for 6 months, with other unspecified treatments considered extra. One user inquired about the source of RU58841.

      community The truth about Dutasteride (w/ sources)

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

      community My Pyrilutamide Experience Update 2, Part 1

      in Update  63 upvotes 1 year ago
      The user's experience taking Pyrilutamide, a drug for hair loss treatment, and their use of it in combination with other treatments such as Minoxidil, Finasteride and RU58841. They have experienced positive results so far with no major side effects.

      community 1 year on fin. No results. I give up.

      in Finasteride/Dutasteride  43 upvotes 2 years ago
      A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

      community 3.5 months Topical Finasteride/Monoxidal

      in Progress Pictures  414 upvotes 2 years ago
      Hair loss treatment with topical finasteride/minoxidil, which had good results after 3.5 months of application. The user also asked if there was any reason to take the oral pill version and if anyone has ever tried mixing them together.

      community PYRILUTAMIDE KX-826 experience

      in Research/Science  98 upvotes 2 years ago
      A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.

      community Stopped minoxidil for a year after a year of using it. Starting again.

      in Minoxidil  158 upvotes 2 years ago
      ? This post by PastelDeUva discusses their experience with Minoxidil and Finasteride for hair loss treatments, which they stopped using for a year before resuming due to family's negative opinion. After restarting, they posted photos of the progression/regression of their hairline and are now planning on adding finasteride and dermarolling in order to get good results.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community I am having Success with RU58841 and 1mm Derma Roller

      in Microneedling  19 upvotes 2 years ago
      A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

      community Finasteride ruined my hair, and my life (so far)

      in Finasteride/Dutasteride  8 upvotes 2 years ago
      The user suspects finasteride worsened their hair loss despite no abnormal shedding and reduced hair fall initially. They are considering various options, including switching brands, trying topical finasteride, oral minoxidil, or waiting for new treatments.

      community Pyrilutamide Phase 3 on its way

      in Treatment  128 upvotes 3 years ago
      Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.