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GlossaryAnagen/Telogen Ratio

measure of hair follicles in growth vs. resting phases

The Anagen/Telogen Ratio is a measure used to assess hair growth and health by comparing the number of hair follicles in the anagen (growth) phase to those in the telogen (resting) phase. A higher ratio indicates a greater proportion of actively growing hair, which is typically a sign of healthy hair growth, while a lower ratio may suggest hair loss or a disruption in the hair growth cycle.

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community Why haven’t we seen anything about this

in Research/Science 18 upvotes 4 years ago

A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

community My Dad seems to get his hair back?

in Question 15 upvotes 5 years ago

A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hair growth.

community How does hair loss and recovery work?

in Chat 12 upvotes 2 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Scientific Review: Caffeine shampoo does NOT stop hair loss. False claims and "fake" research. 19 References included.

in Research/Science 204 upvotes 2 years ago

Alpecin Caffeine shampoo is ineffective for stopping hair loss, with unreliable supporting research. Finasteride is effective in reducing hair loss by lowering DHT levels.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 104 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community 4 years; fin 1mg/day @ 4 years; minox twice daily @ 3 years; estradiol 5mg/day @ 3 months; spiro 100 mg /day @ 3 months (Wet hair because it's easy to hide issues with dry hair)

in Progress Pictures 198 upvotes 3 months ago

The user shared their 4-year hair regrowth progress using finasteride, minoxidil, estradiol, and spironolactone. They noted significant regrowth by the second year and additional benefits from estradiol and spironolactone.

community Fucking hell rosemary how is that possible

in Chat 19 upvotes 2 years ago

User reported hair regrowth and thicker hair after using rosemary oil, zinc, biotin, vitamin D, and a better diet. They believe rosemary oil contributed the most to the improvement.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 674 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 37 upvotes 1 year ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community Sandalore: a scientific homemade approch

20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 6 months ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community Can we trust l’oreal clinical study on Stemoxydine 5%? They conducted/founded the research on the Same molecule that they sell, research could be biased!? L’Oreal reported clinical study that showed an increase of 4% in hair density on the patients treated with stemoxydine for 3 months

in Research/Science 36 upvotes 2 years ago

Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. L'Oreal's study on Stemoxydine 5% claims a 4% increase in hair density after 3 months, but some users question potential bias.

community Is this regrowth? 11 months topical solution (min/fin)

in Is this regrowth? 417 upvotes 1 year ago

The user has been using a topical solution of Minoxidil and Finasteride for hair regrowth for 11 months, applying it three times a week. The responses to the user's question about regrowth are mixed, with some users confirming regrowth and others suggesting it's time to give up.

community 2 years Fin + Minoxidil Regrowth

in Finasteride/Dutasteride 113 upvotes 4 months ago

A user shared their two-year progress using 2.5mg finasteride daily and minoxidil twice daily, recently adding topical dutasteride. Another user questioned the high finasteride dosage, noting no benefits over 1mg.

community 5 Month Dutasteride Progress Before and After

in Progress Pictures 173 upvotes 1 year ago

A user experiencing significant hair loss started using Dutasteride, a drug typically used for prostate issues, and noticed a positive change in hair thickness and volume after 5 months. Other users in the conversation also shared their experiences and observations with Dutasteride, with one mentioning additional use of oral Minoxidil.

community Finally got to see my dermatologist for dutasteride today. He said that dutasteride will not cause a shed. Everyone on Reddit says otherwise.

in Finasteride/Dutasteride 62 upvotes 1 year ago

User lost ground on finasteride, switched to dutasteride. Dermatologist said no shedding, but online experiences differ.

community Finasteride 1mg + Minoxidil 3 month transformation (My story)

in Progress Pictures 2100 upvotes 1 year ago

A user shared a 3-month hair regrowth transformation using Finasteride 1mg, Minoxidil, and occasional derma rolling. Some responders are skeptical of the rapid growth, while others suggest the user might be an exceptional responder to the treatment.

community #BIG4 plus vitamins and biotin/ 6 Months results/ 26 years old/ Extreme MPB

in Progress Pictures 237 upvotes 2 years ago

A 26-year-old with extreme male pattern baldness saw hair regrowth after 6 months using Minoxidil, Finasteride, microneedling, Nizoral, a vitamin complex, biotin, and a shampoo with baicapil. Continuation of treatment is necessary to maintain results; stopping may lead to hair loss, making a hair transplant a potential future option.

community Does Finasteride Sustain Minoxidil-grown Hairs?

in Finasteride/Dutasteride 8 upvotes 1 year ago

The post discusses whether finasteride can maintain hair growth stimulated by minoxidil. The response indicates that finasteride cannot sustain minoxidil-grown hairs.

community piroctone olamine was was very superior than ketoconzole in increasing hairgrowth and reducing itching and danruff?

in Research/Science 15 upvotes 2 years ago

Piroctone olamine is more effective than ketoconazole for increasing hair growth and reducing itching and dandruff. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Using follica’s micro needling device and exosomes injections you’re looking at a 50% or probably more regrowth in male pattern baldness

in Treatment 11 upvotes 4 years ago

Using a combination of micro-needling and exosome injections as a potential treatment for male pattern baldness, which could result in 50% or more regrowth.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 73 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community If finasteride and dutasteride are supposed to maintain the hair that you have, then why do you go through a shedding phase?

in Finasteride/Dutasteride 18 upvotes 1 year ago

Hair loss treatments Finasteride and Dutasteride may cause shedding, but it's a good sign as miniaturized hairs are replaced by thicker ones. Shortness of breath may be experienced from Dutasteride or oral Minoxidil.

community Anyone tried Stemoxydine twice daily?

in Treatment 6 upvotes 3 years ago

The conversation discusses using Stemoxydine, a hair growth stimulant considered weaker than Minoxidil, and questions whether applying it twice daily could improve results similar to twice-daily Minoxidil applications.

community It’s getting worse. (4 months)

in Update 203 upvotes 11 months ago

The conversation discusses hair loss treatments, with users suggesting the use of finasteride daily, considering minoxidil for aggressive hair loss, and discussing the normalcy of shedding during treatment. Some users recommend adding Nizoral shampoo and switching to dutasteride for better results.

community Losing gains from 7 months of oral min, fin, dut.

in Update 66 upvotes 11 months ago

A user reported losing hair after 7 months of using oral minoxidil, finasteride, and dutasteride, but others reassured that this is likely just a shedding phase where old hairs fall out to make way for new growth. Some users experience sheds every 7-8 months and suggest staying consistent with treatment.

community Quit Minoxidil, keep gains w/ Fin and Stemoxydine? | Self-experiment

in Minoxidil 52 upvotes 2 years ago

A user experimenting with quitting using Minoxidil and replacing it with Finasteride and Stemoxydine in order to keep hair loss gains, but other users warning the original poster of potential shedding. Another user suggested phasing out Minoxidil and replacing it with Finasteride and microneedling instead.