Topical Vitamin D3 may stimulate hairgrowth and has been used for Alopecia Areata. There is a question about the lack of research on its use for Androgenetic Alopecia (AGA).
Hairgrowth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).
TDM-105795 showed promising hairgrowth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
The conversation discusses whether drinking coffee affects the hairgrowth benefits of Minoxidil, with one user mentioning that Minoxidil's vasodilation is stronger than caffeine's vasoconstriction, and another sharing personal experience of better hairgrowth after quitting caffeine while on Minoxidil.
A 19-year-old user shared impressive hairgrowth results after using 5% topical minoxidil foam and 1mg finasteride for two months, along with vitamin D. They recommend this regimen for others, noting significant improvements in hair thickness and health.
He Shou Wu (Fo Ti) extract was found to prolong the hairgrowth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.
TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hairgrowth and reduce hair follicle sensitivity to DHT.
Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hairgrowth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.
The conversation discusses using Stemoxydine, a hairgrowth stimulant considered weaker than Minoxidil, and questions whether applying it twice daily could improve results similar to twice-daily Minoxidil applications.
User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hairgrowth improvement.
A 42-year-old man started using RU-58841 for hair loss and saw noticeable results after a month and a half, even his daughter observed hairgrowth. He did not use minoxidil or finasteride due to cost and is considering sharing pictures if improvement continues.
The conversation discusses adding melatonin powder to a topical finasteride solution for hair loss, with one reply suggesting that melatonin may promote faster hairgrowth but advising against mixing it directly into the solution due to potential instability.
The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hairgrowth and density, with considerations for potential skin irritation and interactions between treatments.
The conversation discusses a natural approach to hair loss treatment using rosemary, peppermint oil, derma roller, pumpkin seed oil, and saw palmetto. Commenters note a slight or minor difference in hairgrowth.
A user shared a 3-month hair regrowth transformation using Finasteride 1mg, Minoxidil, and occasional derma rolling. Some responders are skeptical of the rapid growth, while others suggest the user might be an exceptional responder to the treatment.
A user reported that Minoxidil, a hairgrowth treatment, stopped working for them despite initial success. Other users suggested not taking breaks from the treatment, checking for fake products, trying microneedling, using oral Minoxidil, combining Minoxidil with tretinoin, and using finasteride.
The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hairgrowth on the scalp is temporary, while facial hairgrowth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hairgrowth.
A 21-year-old man shared his 2.5-year experience with hair loss treatments, including 1mg Propecia (finasteride) nightly, 12.5% Minoxidil once daily, 2% Nizoral shampoo 2-4 times a week, and later 5% Minoxidil once daily. He experienced minor side effects like watery semen and itchy scalp, and while he's seen fluctuations in hairgrowth, he's generally happy with the results and is considering experimental treatments like CB-03-01 and RU58841.
Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hairgrowth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.
User shared 2-year progress with Dutasteride, 5mg oral minoxidil, and 7 months of RU58841 for hairgrowth. RU58841 was most effective, stopping itching and promoting significant growth.
The conversation discusses hair loss treatments, specifically using minoxidil, finasteride, and dutasteride, and advises patience as results can take up to a year. It also suggests delaying a hair transplant until after a year of medication to establish a stable baseline.
For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.
Hair loss discussion mentions losing 50 strands daily as normal, but varies for individuals. Some users joke about hair loss in other areas, while others emphasize individual differences and hair cycle length.
OP is experiencing ongoing hair shedding despite two years on finasteride, with some initial improvement but no long-term success. Users suggest seasonal shedding, checking for vitamin deficiencies, considering minoxidil, and possibly switching to dutasteride.
A man lost his transplanted hair despite using minoxidil because he wasn't on a DHT blocker like finasteride, which is essential to prevent further hair loss. The conversation emphasizes that hair transplants are not a cure and require maintenance with medications to preserve results.
The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.