Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hairgrowth, could be alternative to Minoxidil and Finasteride.
David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.
The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.
A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.
User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hairgrowth improvement.
He Shou Wu (Fo Ti) extract was found to prolong the hairgrowth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.
TDM-105795 showed promising hairgrowth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
Quitting minoxidil can lead to significant hair loss, even in areas that were not thinning before, as hair becomes reliant on the treatment. Some users also report losing hair gains when stopping minoxidil despite taking finasteride.
Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.
A user's hair loss journey and their results from 9 months of the treatments finasteride and minoxidil, as well as biotin supplementation. People discussed side effects, taking progress pictures, and providing support to other users on their own journeys.
A user's progress with treating hair loss over 3.5 months, which involves taking finasteride MWF, minoxidil daily and microneedling once a week. There was positive feedback from other users regarding the results.
Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.
A user reported that Minoxidil, a hairgrowth treatment, stopped working for them despite initial success. Other users suggested not taking breaks from the treatment, checking for fake products, trying microneedling, using oral Minoxidil, combining Minoxidil with tretinoin, and using finasteride.
Using a combination of micro-needling and exosome injections as a potential treatment for male pattern baldness, which could result in 50% or more regrowth.
Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.
Hair loss treatments, particularly using finasteride and minoxidil. The user has experienced positive results from taking finasteride with no side effects and suggests listening to the podcast of Spencer Kobren for more information on such treatments.
Increased hair fall after starting minoxidil, dutasteride, and biotin is normal. Hair may grow faster, and shaving your head is fine while on these medications.
The conversation discusses hair loss treatments, specifically using minoxidil, finasteride, and dutasteride, and advises patience as results can take up to a year. It also suggests delaying a hair transplant until after a year of medication to establish a stable baseline.
Some people claim Dutasteride worsened their hair loss, causing concern among users. Reasons suggested include initial shedding phases, incorrect attribution to Dutasteride when other factors are involved, genetic variations affecting drug response, and the possibility of non-authentic medication.
The conversation discusses the possibility of transplanting leg and arm hair to the scalp for hair loss treatment. Minoxidil is mentioned as a potential aid for hairgrowth, but concerns about the effectiveness and appearance of body hair on the head are raised.
The conversation discusses microneedling for hair loss, focusing on optimal needle depth and frequency. Users report varying practices, with some using Minoxidil after microneedling and others suggesting different depths and frequencies based on personal tolerance.
A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.
A user with early-stage diffuse hair thinning asked for long-term success stories using treatments like finasteride, minoxidil, and RU58841. One person regained most of their hair after 22 months on finasteride and minoxidil, while another saw significant improvement with oral minoxidil after trying various treatments over many years.
A 37-year-old using Dutasteride and Oral Minoxidil for 6 months to treat hair loss, showing some improvement. The discussion includes differing opinions on the effectiveness of Dutasteride.
The post and conversation are about a user's successful regrowth of hair using topical minoxidil and rosemary shampoo. Other users discuss the potential limitations of minoxidil and recommend using finasteride to maintain hairgrowth.
The conclusion of the conversation is that the user plans to use topical minoxidil, ketoconazole shampoo, and a derma stamp for hair loss treatment. They also plan to start using finasteride in the next 2 months. Other users suggest using finasteride and a hair transplant for better results. The user appreciates the feedback and will continue posting progress.
Anageninc stopping the sale of Pyrilutamide due to a cease and desist order from Kintor, with some speculating that it was either a hoax or subpar product.
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
The conversation discusses the slow transition from baby hair to normal hair while using finasteride and transitioning to dutasteride, with progress except for the crown area. It's mentioned that hair thickening can take years, with each growth cycle potentially making the hair thicker, and this process can span over 6 months or more.