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      community Desensitize Follicle Sensitivity to DHT?

       12 upvotes 3 weeks ago
      Hair follicles cannot be desensitized to DHT like allergies; treatments focus on reducing DHT levels or blocking its effects using methods like finasteride, GT20029, or PROTACs. Topical treatments like ceterizine and BPA application are also mentioned.

      community Amplifica: Hope or Cope? A Review of Their Pipeline

       9 upvotes 1 month ago
      Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

      community 5 years of Minoxidil gains all gone when i stopped

       33 upvotes 1 month ago
      Stopping minoxidil led to hair loss, but restarting it may help regain some hair, though not fully to the previous state. Using finasteride or dutasteride alongside minoxidil can improve chances of recovery.

      community Why am I shedding long healthy hairs ?

       5 upvotes 1 month ago
      The conversation discusses hair shedding while using dutasteride, with users suggesting it's a normal phase that may lead to regrowth. Additional treatments like minoxidil, GHK-CU, and keto shampoo are mentioned to help manage shedding and promote hair growth.

      community Someone please offer reassurance

      in Minoxidil  3 upvotes 1 month ago
      A 19-year-old male is experiencing hair shedding while using oral minoxidil, ketoconazole, dermastamping, and saw palmetto, and is considering switching to finasteride for better results. Users suggest that saw palmetto may not be effective and recommend finasteride instead, while also discussing other treatments like rosemary oil, peppermint oil, and pumpkin seed oil.

      community Creatine and Hair Loss: Are the studies misleading?

       74 upvotes 1 month ago
      Some users believe creatine may cause hair loss, citing anecdotal evidence and criticizing study flaws. Others argue there's no proven link between creatine and hair loss, suggesting any shedding might be due to other factors or genetic predisposition.

      community Wanting to try topical AHK-CU/GHK-CU

       6 upvotes 3 months ago
      The user is exploring topical treatments AHK-CU and GHK-CU for hair loss, avoiding Minoxidil and prescription medications. They believe their hair loss is not genetic but caused by Accutane, and are considering products like Neurogan and Bloom by Fleur.

      community Topical Fin increased hairloss

      in Finasteride/Dutasteride  8 upvotes 3 months ago
      The user experienced increased hair loss with topical finasteride and is considering switching to oral finasteride. Others shared mixed experiences, with some suggesting oral finasteride is more effective, while others noted individual results vary.

      community Why I Take 5mg Minoxidil at Night Instead of Splitting 2.5mg

       9 upvotes 3 months ago
      Taking 5mg oral minoxidil at night instead of splitting 2.5mg doses, with the rationale that a single larger dose may provide a stronger activation for hair follicles and reduce peak-related side effects. Some users report sleep issues with nighttime dosing, while others find it beneficial; opinions on effectiveness and side effects vary.

      community Does anyone use alfatradiol? Does it do anything at all??

       6 upvotes 4 months ago
      Alfatradiol is considered a mild treatment for hair loss, often used alongside other treatments like finasteride, minoxidil, and dutasteride. Users report it helps maintain hair but is not effective for regrowth on its own.

      community Oral daily 1 mg dutasteride with Minoxidil topical solution

      in Minoxidil  4 upvotes 4 months ago
      Oral dutasteride and topical Minoxidil are used to treat hair loss, with the goal of suppressing DHT and improving hair density. The effectiveness depends on genetics and the duration of baldness, and lifelong treatment may be necessary to maintain results.

      community 2-Month Progress: 5% Topical Minoxidil + Microneedling (No Finasteride)

       163 upvotes 4 months ago
      The user shared their two-month progress using 5% topical minoxidil and microneedling, noting significant hair growth without finasteride. Other users discussed the effectiveness and side effects of finasteride, with some suggesting adding it for better long-term results.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 5 months ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

      in Treatment  5 upvotes 5 months ago
      A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

       59 upvotes 5 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Rejux-3x - the copper peptide combo that tressless overlooks.

       1 upvotes 5 months ago
      Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.

      community Now that hair loss in mice is solved, can they move on to people?

       709 upvotes 5 months ago
      Hair loss treatments are being tested on mice, with methods like minoxidil and stem cell therapy showing promising results. However, human trials are still years away, leading to humorous frustration about mice benefiting first.

      community 2 years later and my hair has come back decently…

       127 upvotes 5 months ago
      A 47-year-old experienced significant hair regrowth using a combination of finasteride and minoxidil, despite initial setbacks with scalp inflammation from minoxidil. The treatment improved hair thickness and color, though some sexual side effects were noted.

      community Fin for 7 months and my sclap is now transparent

      in Progress Pictures  16 upvotes 6 months ago
      A 24-year-old male has been using finasteride for 7 months and noticed thinning hair, especially when wet, and is concerned about the effectiveness of the treatment. Suggestions include continuing finasteride, considering minoxidil, and possibly trying micro-needling.

      community Six months progress - oral fin/min

      in Progress Pictures  102 upvotes 7 months ago
      The user shared six months of progress using oral finasteride (1.2mg) and minoxidil (3mg) with positive results. They do not use topical minoxidil and have not experienced side effects like erectile dysfunction.

      community Hairline vs Crown regrowth results

      in Finasteride/Dutasteride  6 upvotes 7 months ago
      The conversation discusses hair loss treatments, including microneedling, Nizoral, LLLT, Minoxidil, and Finasteride. The user experienced initial shedding reduction with Nizoral and LLLT, but shedding resumed with Minoxidil and Finasteride, which is considered a normal part of the treatment process.

      community Early Signs - Notes for diffuse thinners

       11 upvotes 7 months ago
      Diffuse thinning is often due to androgenetic alopecia, and DHT blockers like finasteride are recommended. Treatments mentioned include minoxidil, finasteride, dutasteride, and RU58841, with emphasis on starting early and using a holistic approach.