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      community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

      in Treatment  46 upvotes 3 years ago
      The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

      community Alfatradiol to combat hair loss

       7 upvotes 11 years ago
      Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Alfatradiol is suggested as another potential solution.

      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  2 upvotes 2 days ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community What are your thoughts on this solution?

      in Treatment  15 upvotes 1 month ago
      The conversation discusses hair loss treatments, focusing on the use of Minoxidil, finasteride, and triamcinolone. Concerns are raised about high concentrations of Minoxidil and the long-term use of corticosteroids.

      community GT20029 & KX826 Major Updates from Kintor.

      in Research/Science  103 upvotes 2 months ago
      KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.

      community Simple to add GHK-Cu to RU58841?

      in Product  1 upvotes 2 months ago
      The conversation is about a user seeking advice on adding GHK-Cu to RU58841 for hair loss treatment, while already using oral minoxidil, dutasteride, ketoconazole shampoo, and considering LLLT. They are unsure about the concentration and carrier solution for GHK-Cu.

      community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

      in Finasteride/Dutasteride  49 upvotes 2 months ago
      Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

      community What do you mix your RU58841 powder with?

      in Product  1 upvotes 3 months ago
      RU58841 powder is mixed with a 70% ethanol and 30% propylene glycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 5 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Why you should wait for Min (Keto + Fin only)

      in Ketoconazole  24 upvotes 8 months ago
      The post discusses using ketoconazole and finasteride for hair loss, suggesting waiting to use minoxidil. The user also mentions microneedling and emphasizes confidence over hair appearance.

      community blood DHT levels shot up after doubling dutasteride dosage

      in Finasteride/Dutasteride  20 upvotes 8 months ago
      A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

      community HairCafe was right about trolls on dutasteride

      in Chat  234 upvotes 8 months ago
      A user falsely claimed to use 2.5mg of dutasteride by using someone else's photo, which actually showed results from finasteride. The conversation discusses the challenges and skepticism around hair loss treatments like dutasteride and finasteride.

      community Progress Pics - 2 months on Rogaine

      in Progress Pictures  29 upvotes 9 months ago
      The user has been using dutasteride for almost a year after switching from finasteride and is now also using Rogaine (Minoxidil). They are considering a hair transplant and are inquiring if their crown might thicken enough with current treatments to reduce the need for grafts.

      community Is finasteride from online providers legit ?

      in Female  7 upvotes 11 months ago
      A female with AGA is considering buying finasteride online due to its effectiveness at higher doses, despite concerns about legitimacy and potential scams. She has tried spironolactone without success and is seeking advice on purchasing finasteride from websites like minoxidilexpress.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  141 upvotes 11 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community 2 month progress with Minoxidil and Dermaroller

      in Minoxidil  412 upvotes 1 year ago
      The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.

      community A little thing to cheer you up for the New Year... (2024)

      in Chat  24 upvotes 1 year ago
      The conversation is about coping with hair loss and using treatments like finasteride, minoxidil, derma-rolling, RU58841, and hair transplants or systems. The main message is to do your best with available treatments and not let hair loss prevent you from enjoying life.