community Anyone take this arthritis medication?
Upadacitinib is discussed as a high-risk drug for autoimmune-related hair loss. Ruxolitinib is mentioned as an existing treatment option.
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30 / 1000+ resultscommunity Best available SARD right now?
The user is considering RU58841 and has been using dutasteride since age 17. They are seeking affordable SARD options, mentioning ASC-J9, GT20029, and AH001.
community Has anyone tried Duodart (dutastride + tamsulosin)
The conversation discusses using Duodart (dutasteride + tamsulosin) for hair loss, with side effects like frequent urination and ejaculation issues leading to discontinuation. The user switched to German Avodart and experienced mood and erection side effects, considering adjusting the dosage to three times a week.
community Setipiprant dose?
community Setipiprant usage?
community Indomethacin/Cetirizine
community Gartanin Degrades dht receptor found in mangosteen fruit. Gonna buy the raw powder mix it with castor oil and filter out the rest. And apply topically.
The conversation discusses using gartanin from mangosteen mixed with castor oil to degrade the androgen receptor for hair loss treatment. Alternatives like setipiprant, minoxidil, and dermastamping are also mentioned, with concerns about cost and potential side effects.
community AH-001 another topical AR degrader beside GT20029, completed Phase I
AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.
community An arthritis drug that can be used for Alopecia.
An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.
community sublingual dutasteride to increase bioavailability?
community does anyone here use L-arginine to reduce side effects?
community Setipiprant users
community Can I take only the dutasteride capsule from inside Duodart?
The small soft-gel capsule inside Duodart contains dutasteride, and the powder/beads contain tamsulosin. You can open the large capsule and take only the dutasteride soft-gel.
community What happens if you combine dutasteride and a aromataze inhibitor?
Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.
community Alternatives to oral 5AR inhibitors
The user is exploring alternatives to oral 5AR inhibitors due to side effects, considering topical dutasteride, RU58841, and kx826. They are skeptical about topical dutasteride's effectiveness and systemic absorption.
community Alternative DHT inhibitors when you can't tolerate Fin/Dut
community Why does Procapil have no side effects even though its a 5ar inhibitor?
community Anagenic is trying to compound Gt20029
The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.
community Can i use a dut with tamsulosin?
The conversation is about using a product containing dutasteride and tamsulosin for hair loss. Users discuss separating the components and potential side effects like frequent urination and changes in libido.
community Limiting potassium in diet on oral minoxidil
community Kintor Pharma Announces Completion of Subject Enrollment and Dosing in Phase I Clinical Trial of AR-PROTAC(GT20029) in the US_Kintor Pharmaceutical Limited
Kintor Pharma finished enrolling and dosing participants in a Phase I trial for a hair loss treatment called AR-PROTAC (GT20029). The effectiveness of another drug, pyrilutamide (KX-826), for hair loss will be clearer after a Phase 2 trial expected to complete in January 2023.
community Beta blocker and diuretic to manage oral minoxidil sides?
community Sandalore - efficacy and safety
community Which one is better? Setipiprant or OC000459?
community Ketoconazol + Prictone Olamine serum safety?
community setipiprant
community Has anyone used Setipiprant?
community How is the GT20029 different to pyrilutamide as an androgenic antagonist
GT20029 and pyrilutamide are both androgen antagonists but work differently; GT20029 degrades the androgen receptor, while pyrilutamide blocks DHT from binding. GT20029 is expected to have similar efficacy to CosmeRNA.
community Serenoa repens (Saw palmetto)
Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.
community Drug restored full hair in 23% and over 80% of hair in 55% in 6 months
An arthritis drug restored significant hair in people with alopecia areata, but it is not effective for male pattern baldness. The drug, Upadacitinib, has serious side effects and is expensive.