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      community Anyone tried topical adenosine?

       5 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. User asks for opinions on topical adenosine as a treatment.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 1 year ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community Does Aminexil actually work for hair growth?

       4 upvotes 5 months ago
      Aminexil is considered too expensive for minimal hair growth results compared to topical finasteride and minoxidil. Cheaper alternatives like L’Oréal's version are available.

      community DIY Minoxidil mix with Fin, Caffeine, Cetirizine, and Melatonin?

       4 upvotes 1 year ago
      A user plans to create a custom topical solution by adding finasteride, caffeine, cetirizine, and melatonin to a minoxidil bottle, questioning the stability and effectiveness of this mix. Concerns include potential crystallization and solution muddiness with added ingredients.

      community shampoo with piroctone olamine in US?

      in Product  1 upvotes 9 months ago
      The conversation is about finding a reasonably priced shampoo with piroctone olamine in the US. The user is cautious about trying new or smaller brands.

      community It's always the Mice that gets to grow back hair.

       434 upvotes 10 months ago
      Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

      community AGA evaluation and first steps - BEGINNER MEGAPOST

       80 upvotes 2 years ago
      The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.

      community Even if the new drugs succeed, how are we gonna apply so many topicals?

       11 upvotes 4 months ago
      New hair loss treatments like GT20029, Clascoterone, and PP405 are being discussed, with concerns about how to apply multiple topicals alongside existing treatments like minoxidil and finasteride. Suggestions include creating a routine, mixing treatments, or minimizing redundancy in treatment stacks.

      community Gray market sources to get gt20029 or pp405?

      in Product  2 upvotes 1 year ago
      The conversation is about sourcing gray market compounds, gt20029 and pp405, for hair loss treatment. The user is interested in these compounds despite their unproven status and potential risks.

      community A New Hair Loss Drug Could Cure Balding and Reverse Graying

       367 upvotes 10 months ago
      ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.

      community Could l-arginine be making hairloss worse?

       5 upvotes 8 years ago
      L-arginine may worsen hair loss by potentially increasing testosterone levels, especially in those with a DHT-sensitive gene. Users discuss the effects of increased nitric oxide on hair loss and consider stopping supplements like zinc and l-arginine to see if hair conditions improve.

      community Best minoxidil formulation for best results?

       2 upvotes 1 year ago
      The conversation discusses creating a customized minoxidil formulation with tretinoin, azelaic acid, and caffeine, but there are concerns about foam stabilization due to acidity. The user seeks advice on the best formulation for effective results.

      community Minoxidil alternate approaches

      in Treatment  2 upvotes 11 months ago
      The conversation discusses hair loss treatments, including the use of 2.5mg Dutasteride, 1mg Finasteride, and Minoxidil 5%, with concerns about side effects like water retention and facial changes. The user is considering alternative Minoxidil applications, such as microneedling and sublingual Minoxidil, to minimize side effects.

      community L. reuteri (probiotic for Androgenic Alopecia)

      in Finasteride/Dutasteride  34 upvotes 5 months ago
      L. reuteri, a probiotic, is being explored for its potential benefits in treating androgenic alopecia, possibly enhancing finasteride's effects and reducing inflammation. The user combines this with finasteride, oral minoxidil, and other supplements, noting some improvement in hair loss.

      community Oral Minoxidil (Loxidil) from Thailand just arrived

      in Minoxidil  178 upvotes 2 months ago
      Oral minoxidil (Loxidil) from Thailand is considered legitimate and effective by users, with some experiencing significant hair regrowth. Many users recommend taking 2.5mg daily, often splitting a 5mg pill.

      community The mystery of Azelaic Acid

       5 upvotes 11 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.

      community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

       4 upvotes 1 year ago
      Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.

      community 108 days of dutasteride 0,5 mg daily use 25M

       834 upvotes 1 year ago
      A user experienced positive hair regrowth after 108 days of using 0.5 mg daily Dutasteride and Alpecin caffeine shampoo, without Minoxidil. The discussion included advice on dosage, potential side effects, and comparisons with Finasteride and Minoxidil.

      community Breezula phase 3 results said to be released next month

       26 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community Better Than Minoxidil? Topical Sodium Valproate

       50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 6 months ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community PP405 mechanism question - looking for discussion

       7 upvotes 5 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Clascoterone/ Breezula will it work

      5 months ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.