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      community How far are we from a treatment better than finasteride?

      in Treatment  129 upvotes 1 year ago
      Dutasteride is more effective than finasteride for hair loss as it blocks more of the enzyme causing hair loss. New treatments like stem cell therapies and alternatives to minoxidil are being explored, but major advancements are still years away.

      community What would an actual nuclear stack look like?

       42 upvotes 4 months ago
      The conversation discusses various treatments for hair loss, including high doses of dutasteride, oral minoxidil, RU58841, microneedling, ketoconazole shampoo, and other supplements like pumpkin seed oil and multivitamins. It also touches on more extreme measures like estrogen therapy and castration, with some users emphasizing the importance of overall health and nutrition.

      community I wish I were a man so bad. Life is cruel

       225 upvotes 6 months ago
      A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

      community Hair transplant before and after

       1163 upvotes 1 year ago
      A hair transplant significantly improved the user's appearance, making them look younger. They consistently use oral finasteride and minoxidil, which may have contributed to the results.

      community Most promising cures for baldness as of May 2026

       70 upvotes 3 months ago
      PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

      community Microneedling at .25 everyday before applying Min

      in Minoxidil  26 upvotes 1 year ago
      Daily microneedling at 0.25mm before applying minoxidil is debated, with some suggesting weekly microneedling is safer and more effective. Concerns include potential skin damage and systemic absorption, while alternatives like tretinoin are considered safer for enhancing minoxidil absorption.

      community Has anyone tried this method? I have never heard of this before.

      1 month ago
      The conversation discusses hair loss treatments, focusing on scalp massages to improve blood flow and reduce tension, as suggested in a video by Rob English. However, most users express skepticism, recommending proven treatments like Finasteride, Dutasteride, and Minoxidil instead.

      community When is the cure gonna drop , how much more time

      in Research/Science  112 upvotes 6 months ago
      There is no imminent cure for hair loss, but treatments like Minoxidil, Finasteride, and new drugs such as KX-826, GT-20029, and PP405 are being explored. Current solutions focus on slowing hair loss and stimulating growth, with hopes for better options in the future.

      community Is this Minoxidil good? France

      in Product  6 upvotes 4 months ago
      A 19-year-old in France is experiencing hair loss after COVID-19 and is using Minoxidil, considering Finasteride but facing challenges in obtaining it. Users discuss Minoxidil's effectiveness, potential issues like crystallization, and alternative products like Foligain.

      community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

       17 upvotes 8 months ago
      ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.

      community Pp405 - it has to work. It has to.

       171 upvotes 6 months ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community 2026 Hairloss Nuclear Stack Update

       83 upvotes 6 months ago
      A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.

      community The future of hair loss drugs.

       34 upvotes 7 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.

      community 5 months Finasteride (.5mg) and Minoxidil (2.5mg)

      in Progress Pictures  223 upvotes 9 months ago
      The user experienced significant hair regrowth and improved hair health after 5 months of using 0.5mg finasteride and 2.5mg minoxidil daily, with only minor side effects like reduced libido. The user is optimistic about achieving over 90% regrowth and may not need a hair transplant.

      community Plant-based Exosomes Efficacy Sourced from South Korea

       2 upvotes 1 year ago
      Plant-based exosomes for hair loss lack scientific evidence and are considered high-risk with low evidence. Combining PRF with minoxidil and finasteride is suggested as a better option.

      community What are the upcoming or promising future developments in hair loss?

       31 upvotes 2 years ago
      The conversation discusses potential future hair loss treatments, including SCUBE3, hair follicle cloning, and GT20029, with mentions of past disappointments like CosmeRNA and hopes for treatments like Verteporfin for infinite donor hair.

      community A Short Recap on PP405 and AAD 2026

      in Update 5 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community What are we thinking about combining Oral AND Topical Minoxidil?

       13 upvotes 6 months ago
      Combining oral and topical minoxidil for hair loss may enhance results, but opinions vary on its effectiveness. Some users report benefits, while others see no added value; side effects like insomnia and increased body hair are noted.

      community Some good news for the future.

       98 upvotes 1 year ago
      PP-405, a potential hair loss treatment, shows promise in stimulating dormant hair follicles and may help with various hair loss types. Current treatments like Minoxidil are still recommended as PP-405 is in early trials and may take years to become available.

      community Breezula Phase III 12-Month Data Released by Cosmo Pharma

       42 upvotes 5 months ago
      Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.