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Glossary Adnexa

accessory structures associated with an organ, like hair follicles

Adnexa refers to the accessory structures associated with an organ. In the context of hair and skin, adnexa includes structures like hair follicles, sebaceous (oil) glands, and sweat glands. These components play crucial roles in the health and function of the skin and hair, contributing to processes like hair growth, lubrication, and temperature regulation.

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community Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?

5 upvotes 4 years ago

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

community Adding dut with fin to stop dht itch

2 upvotes 2 years ago

A user is seeking advice on adding dutasteride to their finasteride regimen to stop DHT-related scalp itch. They have tried selenium sulfide and ketoconazole shampoos with temporary success.

community ND dropped ecklonia cava which can cause hair growth. Alternative to fin/dut for those who have side effects

6 upvotes 1 year ago

Ecklonia cava is suggested as an alternative to finasteride and dutasteride for hair growth, potentially offering benefits without their side effects. It is promoted for anti-aging, mood enhancement, and cognitive support.

community a new supplement just released

12 upvotes 8 years ago

A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

community Published in Nature: Osteopontin, a protein involved in the growth of hair on moles could be the key to our troubles.

13 upvotes 3 years ago

Osteopontin, a protein involved in hair growth on moles, may help with hair loss. However, it is also linked to Alzheimer's, cancer, and bone development, so caution is advised.

community After almost 4 months on fin, it looks like I might be unlucky enough to develop early sings of gyno...

6 upvotes 6 years ago

After nearly four months on finasteride, a user noticed improved hair quality but developed nipple puffiness, suggesting early signs of gynecomastia. They considered switching to other treatments like CB-03-01 or RU58841 and contemplated consulting an endocrinologist about aromatase inhibitors.

community Annurca Nutraceutical and hair

18 upvotes 8 years ago

Apple core extract pills, believed to enhance hair density, are discussed as a potential treatment for hair loss. Users express cautious optimism and interest in trying the product, while acknowledging skepticism and the high cost.

community DHT Itch flareups and information

in Research/Science 4 upvotes 1 month ago

DHT itch often occurs in cycles or flare-ups, particularly around the temples and crown. Treatments like finasteride, dutasteride, and topical minoxidil can reduce or eliminate the itch.

community oral hyaluronic acid supplements?

5 upvotes 4 years ago

Oral hyaluronic acid is not beneficial for hair, as it gets broken down in the stomach and has no strong evidence supporting its effectiveness. The user is taking finasteride, dutasteride, and topical minoxidil for hair loss, but combining finasteride and dutasteride is considered redundant.

community Dutasteride and anal with partner

in Satire 119 upvotes 5 months ago

Using dutasteride anally as a hair loss treatment, with humorous and satirical comments on its effects and implications.

community ASCEplus HRLV Exosomes with microneedling

1 upvotes 2 years ago

The discussion is about using ASCEplus HRLB exosomes for hair loss treatment, which combines 10 billion exosomes with growth factors, nutrients, biotin, and copper tripeptide. The treatment is expensive and typically administered via scalp injections, but in Europe, it's done with microneedling.

community very interesting thats why i added NAC and quercetin to my supp regime

38 upvotes 6 years ago

The conversation discusses using NAC and quercetin as supplements for hair loss, with some users also mentioning finasteride. NAC is highlighted for its potential benefits, but concerns about its safety and absorption are also raised.

community Dutasteride mesotherapy alongside oral fin and dut?

2 upvotes 8 months ago

Dutasteride mesotherapy, combined with peptides and exosomes, is being considered for hair loss treatment. One user suggests that oral finasteride or dutasteride mesotherapy may not be necessary if already taking oral dutasteride.

community Prostate aches on oral finasteride

in Finasteride/Dutasteride 6 upvotes 3 weeks ago

The conversation discusses prostate aches experienced by someone taking oral finasteride for hair loss, with users suggesting the aches may be due to prostate size reduction. Some users share similar experiences, while others express skepticism about the side effects.

community Eyebrows and Lashes growing a bit too much

4 upvotes 2 weeks ago

Minoxidil use led to significant eyelash and eyebrow growth, making the user appear more feminine. The user hopes for similar results on scalp hair.

community Does anyone else sneeze or have their nose run when they microneedle their scalp?

in Microneedling 23 upvotes 2 years ago

Microneedling the scalp can cause sneezing, runny nose, and watery eyes due to nerve stimulation, histamine release, reflex actions, or sinus relief. Several users experience similar symptoms.

community High Estrogen and Test on Dut 5x a week

6 upvotes 1 year ago

A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

community Testicular Ache

3 upvotes 7 years ago

The user has been taking 0.5 mg of finasteride daily for two months and is experiencing testicular ache, which they believe might be related to the medication. They plan to continue the treatment for a few more months despite the discomfort, hoping the side effects will subside.

community Added Dut 1x Weekly to Daily Fin (6mo Report)

in Progress Pictures 6 upvotes 2 months ago

The user has been using finasteride daily for four years and added dutasteride once a week, noticing minimal changes in hairline but reduced shedding. They are considering adding oral minoxidil but prefer to avoid it due to potential side effects.

community Could fatty liver(other issues related to it..)play a role in Dupa/Aga?

6 upvotes 1 year ago

Fatty liver and related issues may influence hair loss conditions like Dupa/Aga. Treatments discussed include Minoxidil, finasteride, RU58841, myo-inositol, and L-glutamine.

community Collagen peptides: Yay or nay?

5 upvotes 6 years ago

Collagen peptides may help with hair growth, but results vary; some users noticed less hair fall and improved nail strength. Minoxidil is suggested for regaining hair thickness lost from accutane.

community What is everyone's assessment of pyrilutamide 1.0% topical as a adjunct treatment?

5 upvotes 3 months ago

The conversation discusses the use of pyrilutamide as an adjunct treatment for hair loss, particularly for those already using finasteride and minoxidil. Users share mixed experiences, with some reporting side effects like numbness and gynecomastia, while others note its potential benefits in reducing shedding and scalp itchiness.

community AH-001 another topical AR degrader beside GT20029, completed Phase I

8 upvotes 10 months ago

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

community Why is Kopexil (trade name Aminexil) not approved as a drug in the US and Europe?

3 upvotes 10 months ago

Kopexil (Aminexil) is not approved as a drug in the US and Europe because it is marketed as a cosmetic, which requires less testing and regulation. L'Oreal's 1.5% Aminexil is noted to reduce hair shedding, but its efficacy as a drug is not proven.

community 2 % fucoidan significantly alleviated AGA symptoms, promoted hair growth, and increased hair density

21 upvotes 11 months ago

2% fucoidan alleviated AGA symptoms, promoted hair growth, and increased hair density in mice. Fucoidan is considered safe for humans as a supplement and topical skincare product, with potential therapeutic effects against AGA.

community Adding dutasteride to fin regimen

in Finasteride/Dutasteride 5 upvotes 1 month ago

The conversation discusses adding dutasteride to a finasteride regimen for potential hair regrowth or thickening. Some users report positive results with the combination, while others caution about side effects like reduced libido.

community Anyone else have sneezing reflex when starting microneedle?

in Microneedling 55 upvotes 2 years ago

Microneedling can cause a sneezing reflex due to tingling in the nose. Users report this reaction, especially in the temple region.

community Hives/Rash from Kx 826 Pyrilutamide???

1 upvotes 1 year ago

OP developed hives after using Kx 826 (Pyrilutamide) 1% twice daily for 3 weeks. The hives appeared on the arms, chest, and groin area.

community 22M, 6 months on dut, is this a W?

in Progress Pictures 3 upvotes 2 months ago

A 22-year-old male has been using oral dutasteride, oral minoxidil, topical minoxidil, and supplements for hair loss, experiencing shedding but some regrowth on the temples. Despite concerns about starting dutasteride, he is seeing positive results and hopes for long-term success.

community The 'DHT itch' is real - notes from a casual bodybuilder

in Chat 115 upvotes 1 year ago

The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.