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GlossaryAlpha-blockers

medications that relax blood vessels by blocking norepinephrine

Alpha-blockers, also known as alpha-adrenergic antagonists, are medications that relax certain muscles and help small blood vessels remain open. They work by blocking the action of norepinephrine, a hormone that tightens the muscles in the walls of smaller arteries and veins. This can improve blood flow and lower blood pressure, making them useful in treating conditions like hypertension and benign prostatic hyperplasia (BPH).

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Tracking 12 products like 8 Maxogen-X, 11 Duderma, 83 DualGen-15 NO PG, 89 DualGen-15 NO PG Plus and 379 KX-826 DHT Blocker Hair Thickening,3 Days Oil Control from by companies like MinoxidilMax and Amazon. View all 12 products »

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community 10 Days Post-Op: Hair Transplant Results and Experience

in Progress Pictures 507 upvotes 3 months ago

A user shared their positive experience with a hair transplant at Dr. Resul Yaman Hair Clinic in Istanbul, including before and after photos. They are considering taking oral Minoxidil post-operation but are avoiding Finasteride due to side effects.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 1 month ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community So we’re just ok with taking a research chemical now?

in Treatment 177 upvotes 3 years ago

The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

community 11 weeks post op !!!! What you think ?

in Is this regrowth? 66 upvotes 3 months ago

A user shared their 11-week post-op hair transplant results, noting they use only vitamins, not minoxidil or finasteride. Replies suggest starting finasteride to maintain results, with mixed opinions on the current progress.

community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 7 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 4 months ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community I just got back from the animal hospital and lost my cat

in Minoxidil 475 upvotes 8 months ago

A user shared a tragic experience where their cat died after being exposed to Minoxidil, warning others of its toxicity to pets. Some users discussed switching to oral hair loss treatments, while others expressed condolences and shared their own concerns and experiences with topical treatments around pets.

community 5 years of min / finasteride, no longer slowing loss.

in Finasteride/Dutasteride 37 upvotes 1 year ago

A user's experience of slowing hair loss while taking minoxidil and finasteride, and the various treatments suggested to help halt or reverse the process.

community Just had this wild thought come into my head.

in Satire 403 upvotes 7 months ago

The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

community Testosterone is 1600, would taking low dose anti-androgens be a viable treatment option for people who’s T spikes on DHT-blockers?

in Treatment 46 upvotes 1 year ago

The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.

community DHT blockers for women, and your experiences with them?

in Female 7 upvotes 4 years ago

A user shared their experience with Spironolactone for hair loss, noting it stopped hair loss and cleared acne but had side effects like frequent urination and potential kidney damage. They also mentioned Bicalutamide as a potentially more potent DHT blocker with fewer side effects and asked for others' experiences with DHT blockers for women.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 47 upvotes 4 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community I’m going balls to the wall with probably the most nuclear stack apart from hormone blockers, will update this thread monthly.

in Treatment 52 upvotes 2 years ago

A user experimenting with an extreme hair loss treatment stack of Dutasteride, RU58841, 15 mg oral minoxidil, and microneedling, which sparked a debate among other users about the safety of this approach.

community Do I get a hair transplant at 22?

in Transplants 11 upvotes 6 months ago

A user has been using dutasteride and oral minoxidil for hair loss with no change and is considering a hair transplant at age 22. Replies suggest that a transplant is possible if DHT blockers like finasteride are continued, and another user shared a positive personal experience with a transplant at age 20.

community August 2021 - August 2024. 23 year old male. 0.5 fin & 2.5 min daily. 0.5 Dut twice a week.

in Progress Pictures 23 upvotes 1 month ago

A 23-year-old male reported significant hair improvement using 0.5 mg finasteride and 2.5 mg minoxidil daily, along with 0.5 mg dutasteride twice a week. He noticed increased hair thickness, density, and darker color, attributing the changes mainly to oral minoxidil and DHT blockers.

community Did quitting caffeine turn me into a minoxidil responder?

in Minoxidil 2 upvotes 7 months ago

A user shared that after quitting caffeine and restarting oral minoxidil, they experienced significant hair regrowth, suggesting that caffeine might interfere with minoxidil's effectiveness by blocking adenosine receptors. They also mentioned side effects like water retention and dizziness, which subsided after a few weeks, and are not using any DHT blockers.

community 3 months in and I think there’s a slight difference. Microneedling 1xweek and minox twice a day

in Progress Pictures 191 upvotes 2 years ago

Using Microneedling 1xweek and Minoxidil twice a day as treatments for hair loss, along with DHT blockers such as Finasteride or Dutasteride. Advice was also given to not raise eyebrows when evaluating hair growth progress.

community 3 months of Min 2x daily, micro needling 1x weekly, and Ketoconazole shampoo 2-4x weekly. Definitely a big confidence boost and worth trying out!

in Progress Pictures 118 upvotes 1 year ago

The progress of a user who has been using Minoxidil, micro needling and ketoconazole shampoo for 3 months to improve their hair and confidence; other users have suggested different treatments such as DHT blockers or finasteride.

community Anyone else’s beard took a huge hit on finasteride or dutasteride? Would minoxidl hepl?

in Progress Pictures 105 upvotes 1 year ago

The effects of finasteride and dutasteride on beard growth, whether minoxidil would help with facial hair loss caused by DHT blockers, and anecdotal evidence from users who have experienced either decreased or increased facial hair density while using these treatments.

community Waterman's Grow Me Shampoo - Snake Oil?

in Advice 6 upvotes 4 years ago

A user has been using Waterman's Grow Me Shampoo, which claims to have DHT blockers and promote hair growth. They've noticed potentially faster hair growth and some new hairs but are unsure if the product is effective or not.

community Started my hair (fin+min+derma) regrowth journey today. Any advice?

in Treatment 7 upvotes 2 years ago

A 16-year-old started using topical finasteride, minoxidil, and dermapen for hair regrowth, along with natural DHT blockers. Advice given includes being patient and considering waiting until 18-21 to use finasteride.

community Hello again with my second journey

in Transplants 78 upvotes 5 months ago

A user underwent a second hair transplant for increased density and to address hair loss in the crown area, with 3,800 grafts at a cost of 2,200 euros at Estepalace, including additional services. Some commenters discussed the appearance of the hairline and the importance of using DHT blockers like finasteride or dutasteride post-transplant.

community Can you beat this 104 year old man‘s hair count?

in Styling 746 upvotes 2 years ago

A 104 year old man's impressive head of hair and speculations about how he has been able to maintain it; treatments such as minoxidil, finasteride, RU58841, dutasteride, 5-AR blockers, and other supplements are discussed.

community Anything stronger than DUT out there?

in Finasteride/Dutasteride 14 upvotes 6 months ago

The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

community My DHT-blocking protocol, I'm exited!

6 upvotes 4 years ago

The post discusses a hair loss treatment regimen using saw palmetto, pumpkin seed oil extract, EGCG (green tea) extract, grape seed oil extract, rosemary oil extract, and Zix. The user plans to use these DHT-blockers and 5AR inhibitors for six months and report the results.

community Whats best vitamins and supplements before and after hair transplant?

in Transplants 9 months ago

The user's first hair transplant failed, and they are preparing for a second one. They are considering whether to continue multivitamins and B complex before the surgery, and are asking for advice on supplements to take for hair loss that do not include DHT blockers, finasteride, minoxidil, or high-dose biotin, and are contemplating iron, folic acid, vitamin C, and NAC for before and after the surgery.

community Will hair regenerate if androgen receptors are nuked?

in Research/Science 9 upvotes 1 year ago

Treatments for hair loss, such as using AR receptor blockers and degraders, to see if follicles can regenerate in the long term. The conversation also discusses how hair transplants could be a potential solution.

community 4 months on 2.5 mg OM, no improvement

in Minoxidil 6 upvotes 1 year ago

After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.

community Why did hair started growing on my neck after taking a mix of saw palmetto, green tea, horsetail and biotin? Is it a good sign?

in Is this regrowth? 1 month ago

A user experienced hair growth on their neck after taking saw palmetto, green tea, horsetail, and biotin. They are curious if this is a good sign and why it happened.

community Any Male Users of Topical Spironolactone Here? I might want to give it a shot

in Treatment 5 upvotes 5 days ago

A user discusses their current hair loss treatment of topical minoxidil, tretinoin, and dermarolling, and considers adding topical spironolactone due to concerns about finasteride's mental side effects. Other users advise against topical spironolactone, citing ineffectiveness and unpleasant smell.