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Did you mean 5 alpha-reductase inhibitors?

Glossary5α-reductase inhibitors

block enzyme converting testosterone to hair-loss-causing DHT

5α-reductase inhibitors, also known as 5-ARIs, are medications that block the enzyme 5α-reductase. This enzyme converts testosterone into dihydrotestosterone (DHT), a hormone that can contribute to conditions like male pattern baldness and benign prostatic hyperplasia (BPH). By inhibiting this enzyme, 5-ARIs can help reduce hair loss and shrink an enlarged prostate.

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community blood DHT levels shot up after doubling dutasteride dosage

in Finasteride/Dutasteride 20 upvotes 7 months ago

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

community Microneedling + Min 2 months progress

in Progress Pictures 1064 upvotes 1 year ago

The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.

community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 9 months ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community Ru, Stemoxydine or Alfatradiol? What has your experience been with any of these 3?

in Treatment 3 upvotes 1 year ago

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

community Has anyone ever tried using (all topicals) finasteride + minoxidil + rosemary oil + castor oil + stemoxydine all over the course of a few months/years?

in Treatment 3 upvotes 8 months ago

The user is using topical finasteride and minoxidil for hair loss and is considering adding rosemary oil, castor oil, and stemoxydine to their routine. They are asking if anyone has experience with this combination or a similar one.

community [M19] five months progress on fin+ oral minoxidil

in Progress Pictures 34 upvotes 1 year ago

User reports five months progress on finasteride and oral minoxidil, with thicker hair and no visible scalp. Started at 2.50mg and increased to 10mg without side effects.

community 8 months on minoxidil and 4.5 months on finasteride

in Update 485 upvotes 2 years ago

Franquito1624: Topical minoxidil and finasteride orally This user, Franquito1624, reported 8 months of using Minoxidil topically and 4.5 months of using Finasteride orally with good results. Other users commented on their success and asked questions about the treatments used.

community Approximately 1 month on oral dut+ oral min

in Progress Pictures 103 upvotes 6 months ago

A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.

community What treatment helped you with oily scalp/hair loss?

in Chat 8 upvotes 6 months ago

The user has been dealing with an oily scalp, seborrheic dermatitis, and hair loss for 18 months, using finasteride without improvement. Another user suggested dutasteride for reducing scalp oiliness.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 2 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community 3 Months Pyrilutamide(1.5 Months 1% ) + Alfatradiol 0.1% + Minoxidil

in Treatment 102 upvotes 1 month ago

The conversation discusses using Pyrilutamide, Alfatradiol 0.1%, and Minoxidil for hair loss treatment. Pyrilutamide is described as a strong antiandrogen, and Alfatradiol is noted for its effectiveness in inhibiting DHT on the scalp.

community Need advice with finishing off my hair loss :)

in Treatment 8 upvotes 3 years ago

User is a Norwood 2-2.5, using 1.25 mg finasteride and 5% minoxidil lotion daily since June last year, experiencing significant regrowth. They are considering additional treatments like saw palmetto, microneedling, dutasteride, aminexil, stemoxydine, mesotherapy, ketoconazole shampoo, and alfatradiol to improve hair thickness.

community Write down your routine to fight agains hair loss

in Chat 16 upvotes 3 years ago

The conversation is about personal routines to combat hair loss, including treatments like Minoxidil, Finasteride, RU58841, vitamins, and dermastamping. Specific methods vary, with some using daily topical applications, oral medications, and weekly procedures like dermarolling and special shampoos.

community Found a Pharmacy that will mix me 0.1 % Alfatradiol (Pantostin)

in Treatment 6 upvotes 3 months ago

The user is currently using 0.025% Pantostin but plans to switch to 0.1% Alfatradiol. They will also use high-dose Kx826, high-dose Minoxidil, and aggressive microneedling for hair regrowth.

community High Dose 0.1% Alfatradiol + 1% Pyrilutamide stopped my Hairloss completely

in Treatment 31 upvotes 1 month ago

Using 0.1% Alfatradiol and 1% Pyrilutamide stopped hair loss, reducing shedding from over 150 hairs a day to less than 10, with no side effects. The user also uses Minoxidil and microneedling, applying the treatments twice daily.

community Non-Fin Super Regimen (Fluridil, Min, Stem, Niz, Viviscal, Broccoli Sprouts, Derma)

in Product 14 upvotes 3 years ago

Hair loss treatments discussed include Fluridil, Minoxidil, Stem, Niz, Viviscal, Broccoli Sprouts, and Derma. One user claims most treatments are ineffective, while another supports Eucapil.

community Megadosing Koshine826(Pyrilutamide), my Plan.

in Treatment 1 upvotes 3 months ago

The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

community Why I believe alfatrodial and fluridil combined with minoxidil is an effective treatment. My experience.

in Research/Science 11 upvotes 4 months ago

The user believes that combining alfatrodial and fluridil with minoxidil effectively maintains hair, based on their 7-year experience. They suggest this combination for those who can't tolerate finasteride.

community Is Fluridil truly void of side effects?

in Chat 6 upvotes 3 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. User considers trying Fluridil, questioning if it has no side effects.

community MinoxidilMax just launched a 0.3% tretinoin topical. Would you try?

in Treatment 16 upvotes 3 years ago

The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.

community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?

in Minoxidil 36 upvotes 1 month ago

Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.

community Shampoo except ketoconazole that works

in Product 8 upvotes 7 months ago

The conversation is about seeking shampoos that help with hair loss or hair thickening without ketoconazole, suggesting alternatives like minoxidil, finasteride, or stemoxydine. One reply suggests that most hair loss shampoos don't work as claimed.

community Fluridil arrived. Hope it doesn't break my dick

in Update 6 upvotes 3 years ago

User tries Fluridil for hair loss after topical finasteride caused issues. Others doubt its effectiveness and cost.

community 18 months. Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL

in Progress Pictures 168 upvotes 4 years ago

A 28 year old man's 18-month journey to treat his hair loss with Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral and T/GEL. He experienced some side effects along the way, including translucent semen and scalp less oily.

community Improve my stack (without Minoxidil)

in Product 37 upvotes 1 year ago

The conversation discusses improving a hair loss treatment stack without using Minoxidil. Microneedling is suggested, Alpecin is deemed ineffective, and there are concerns about the safety of Minoxidil compared to finasteride.

community Hair much worse after 6 months?

in Progress Pictures 230 upvotes 1 year ago

A user experienced significant hair loss after 6 months of using 0.5mg finasteride daily. Suggestions from others included trying Dutasteride and Minoxidil, getting professional help from a dermatologist, and addressing high iron levels that could be contributing to the hair loss.

community 5 months finastiride + 2.5 months minoxidil and microneedling

in Progress Pictures 59 upvotes 2 weeks ago

The user is using finasteride (1 mg daily), topical minoxidil, and microneedling with a derma stamp for hair loss. They reported shedding stopped and new hair growth appeared after a few months, with no side effects.

community 5 month progress! (5% Min, 1mg Fin, Nizoral)Alexa play Don’t Stop Believing

in Progress Pictures 146 upvotes 2 weeks ago

The user experienced significant hair regrowth using 5% Minoxidil, 1mg Finasteride, and Nizoral, with minimal side effects like occasional dandruff. Shedding occurred initially but led to positive results over time.

community 5-month finasteride - diffuse thinning update

in Progress Pictures 16 upvotes 1 month ago

The user shared a 5-month update on using finasteride, minoxidil, and ketoconazole shampoo for diffuse thinning, along with supplements like B-Vitamins, D-Vitamins, Iron, and Beta carotene. They noted improvement in hair condition and encouraged others to check previous posts for more information.

community 5 months progress on fin and min

in Progress Pictures 1794 upvotes 1 month ago

Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.