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    Did you mean 5-alpha reductase deficiency?
    Glossary5α-reductase deficiency

    genetic condition impairing testosterone conversion to dihydrotestosterone (DHT)

    5α-reductase deficiency is a genetic condition where the body lacks sufficient levels of the enzyme 5α-reductase, which is crucial for converting testosterone into dihydrotestosterone (DHT). This deficiency can lead to atypical development of male genitalia in utero and can affect secondary sexual characteristics during puberty.

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      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 1 month ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community 8 months on minoxidil and 4.5 months on finasteride

      in Update  485 upvotes 2 years ago
      Franquito1624: Topical minoxidil and finasteride orally This user, Franquito1624, reported 8 months of using Minoxidil topically and 4.5 months of using Finasteride orally with good results. Other users commented on their success and asked questions about the treatments used.

      community Started Finasteride almost three months ago and I'm upset

      in Update  153 upvotes 8 months ago
      A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

      community Approximately 1 month on oral dut+ oral min

      in Progress Pictures  103 upvotes 5 months ago
      A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.

      community blood DHT levels shot up after doubling dutasteride dosage

      in Finasteride/Dutasteride  20 upvotes 6 months ago
      A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

      community Microneedling + Min 2 months progress

      in Progress Pictures  1071 upvotes 1 year ago
      The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.

      community What treatment helped you with oily scalp/hair loss?

      in Chat  8 upvotes 5 months ago
      The user has been dealing with an oily scalp, seborrheic dermatitis, and hair loss for 18 months, using finasteride without improvement. Another user suggested dutasteride for reducing scalp oiliness.

      community Need advice with finishing off my hair loss :)

      in Treatment  8 upvotes 3 years ago
      User is a Norwood 2-2.5, using 1.25 mg finasteride and 5% minoxidil lotion daily since June last year, experiencing significant regrowth. They are considering additional treatments like saw palmetto, microneedling, dutasteride, aminexil, stemoxydine, mesotherapy, ketoconazole shampoo, and alfatradiol to improve hair thickness.

      community Write down your routine to fight agains hair loss

      in Chat  15 upvotes 3 years ago
      The conversation is about personal routines to combat hair loss, including treatments like Minoxidil, Finasteride, RU58841, vitamins, and dermastamping. Specific methods vary, with some using daily topical applications, oral medications, and weekly procedures like dermarolling and special shampoos.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 2 months ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Is Fluridil truly void of side effects?

      in Chat  6 upvotes 3 years ago
      Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. User considers trying Fluridil, questioning if it has no side effects.

      community MinoxidilMax just launched a 0.3% tretinoin topical. Would you try?

      in Treatment  14 upvotes 3 years ago
      The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.

      community Shampoo except ketoconazole that works

      in Product  9 upvotes 6 months ago
      The conversation is about seeking shampoos that help with hair loss or hair thickening without ketoconazole, suggesting alternatives like minoxidil, finasteride, or stemoxydine. One reply suggests that most hair loss shampoos don't work as claimed.

      community Improve my stack (without Minoxidil)

      in Product  36 upvotes 11 months ago
      The conversation discusses improving a hair loss treatment stack without using Minoxidil. Microneedling is suggested, Alpecin is deemed ineffective, and there are concerns about the safety of Minoxidil compared to finasteride.

      community Hair much worse after 6 months?

      in Progress Pictures  230 upvotes 1 year ago
      A user experienced significant hair loss after 6 months of using 0.5mg finasteride daily. Suggestions from others included trying Dutasteride and Minoxidil, getting professional help from a dermatologist, and addressing high iron levels that could be contributing to the hair loss.

      community 5-month finasteride - diffuse thinning update

      in Progress Pictures  15 upvotes 1 week ago
      The user shared a 5-month update on using finasteride, minoxidil, and ketoconazole shampoo for diffuse thinning, along with supplements like B-Vitamins, D-Vitamins, Iron, and Beta carotene. They noted improvement in hair condition and encouraged others to check previous posts for more information.

      community 5 months progress on fin and min

      in Progress Pictures  1781 upvotes 3 weeks ago
      Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.

      community 5 month hair progress on fin+min

      in Progress Pictures  616 upvotes 1 month ago
      The user shared their 5-month hair progress using oral finasteride and minoxidil, reporting positive results with minimal side effects. They use a chewable 2-in-1 product from Hims for convenience.