30 citations
,
December 1972 in “Archives of dermatology” This report examines efforts to enhance the efficacy of topical steroids for alopecia areata using penetration-enhancing vehicles and exceptionally high concentrations, noting systemic steroids often lead to relapses and toxicity.
4 citations
,
December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that persistent activation of Wnt signaling in mouse models leads to cyst formation in hair follicles, resembling acne, and that these cysts can be partially reduced by certain acne treatments.
1 citations
,
October 2020 in “Research Square (Research Square)” This study found that abnormal Wnt signalling in stem cells may contribute to blackhead formation in acne by inhibiting cell differentiation and causing cell accumulation in the junctional zone.
103 citations
,
September 2004 in “Clinics in dermatology” This article discusses methods to measure comedogenesis in acne through the presence of microcomedones and reports no new clinical results; the authors outline a skin surface biopsy technique using cyanoacrylate gel.
January 2011 in “The Chinese Journal of Dermatovenereology” This study found that curcuma anti-acne gel reduced comedo formation and improved skin characteristics in a rabbit ear acne model, showing potential for treating acne.