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In this study, cultured skin equivalents with ovine hair follicle dermal papillae grafted onto nude mice developed follicle-like structures, suggesting a potential model for studying hair follicle development.

This study observed that a novel extracellular matrix hydrogel made from human fibroblast-derived matrix improved wound healing in animal models, showing significant effects such as hair follicle formation, reduced inflammation, enhanced pro-healing growth factor levels, and interaction with macrophages, compared to traditional collagen hydrogels.

This study found that generating pluripotent stem cell-derived skin organoids in a 3D bioprinted hydrogel device improved keratinocyte differentiation and hair follicle formation while reducing necrosis.

This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.

This study found that engineered skin substitutes made with skin-derived precursors and epidermal stem cells can regenerate hair follicles after grafting into nude mice.