6 citations
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December 2016 in “Journal of Obsessive-Compulsive and Related Disorders” This study found that adults with trichotillomania did not show differences in pain tolerance or exhibit analgesia to cold pressor pain compared to healthy controls.
March 2026 in “Journal of Pain” Preoperative stress markers alone don't predict chronic post-surgical pain.
49 citations
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July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
March 2025 in “Journal of Dermatological Treatment” In this case report, a patient required more local anesthetic than usual for hair transplant surgery, which the authors suggest may be due to cannabis use impacting pain sensitivity and anesthetic clearance.
64 citations
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July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.