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research P.1.g.018 Cognitive performance in adolescents with anorexia nervosa: subgroups in relation to neuropsychological impairment

August 2008 in “European Neuropsychopharmacology”

This study identified significant correlations between self-esteem, psychiatric symptoms, and health-related quality of life in peritoneal dialysis patients.

Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

13 citations , January 2020 in “Neuroscience”

This study found that finasteride impaired object recognition memory and altered hippocampal dendritic structures in male 3xTg-AD mice, suggesting potential sex differences in Alzheimer's disease pathology.

research Beyond Perceived Stress: Hair Cortisol is linked with Cognition and Fatigue in Black and White Patients with Multiple Sclerosis

June 2026 in “Psychoneuroendocrinology”

In this study involving patients with Multiple Sclerosis, higher hair cortisol levels and being Black were linked to poorer cognitive performance, while increased perceived stress and depression were associated with greater fatigue, highlighting distinct associations between objective and subjective stress measures and MS-related outcomes.

Local Synthesis and Function of Neuro-Estrogen and Neuro-Androgen: Impact on Hippocampus-Related Cognition and Neuronal Plasticity

research Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity

January 2026 in “Frontiers in Cellular Neuroscience”

This study discusses the complex roles and effects of brain-synthesized sex neurosteroids, highlighting sex differences in their concentrations and their varied impacts on synaptic plasticity, cognitive behavior, and aging-related cognitive decline.

research Androgen treatment of postmenopausal women

28 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

This review presents substantial evidence supporting testosterone use for hypoactive sexual desire disorder in postmenopausal women, but notes safety concerns with off-label prescribing due to lack of approved formulations.

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Community Join

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community Why is sexual functioning the main concern? Fin/dut can affect cognition and mood, arguably being more important

in Finasteride/Dutasteride 65 upvotes 5 months ago

Finasteride and dutasteride can affect sexual function, cognition, and mood. Alternatives like minoxidil, pyrilutamide, and alfatradiol have varied effectiveness and side effects.

community Do creatine increase testosterone and dht?

4 upvotes 5 months ago

Creatine does not increase testosterone or DHT, and there is no evidence it causes hair loss. Some users report improved gym performance and mood with creatine, while others are concerned about potential hair loss, but scientific research does not support these concerns.

community 2.5 years on topical finasteride (0.1% fin + 7% min): hair success and why I stopped

in Finasteride/Dutasteride 20 upvotes 8 months ago

Topical finasteride with minoxidil effectively stabilized and thickened hair but caused side effects like brain fog, reduced libido, and emotional flattening, leading to discontinuation. The user switched to a new regimen including minoxidil, KX-826, and other treatments, noting improvements in libido and vivid dreams after stopping finasteride.

community Creatine causes hair loss zzzzz

87 upvotes 10 months ago

Creatine is humorously blamed for hair loss, with users sharing exaggerated and satirical experiences. Some users report no hair loss with creatine, while others mention using treatments like minoxidil and finasteride to manage hair loss.

community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 1 year ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

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