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research Circadian clocks: from stem cells to tissue homeostasis and regeneration

84 citations , December 2017 in “EMBO Reports”

This review discusses the role of circadian rhythms in stem cell differentiation and tissue regeneration, emphasizing their impact on organ physiology and aging, but reports no new experimental results.

research Identification of lncRNAs involved in the hair follicle cycle transition of cashmere goats in response to photoperiod change

1 citations , May 2025 in “BMC Genomics”

In this study, researchers identified key lncRNAs and target genes potentially involved in the transformation of the hair follicle cycle, which could advance understanding of lncRNAs' roles in hair follicle development.

research The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway

January 2024 in “Cells”

This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.

research Therapeutic Application of Microsponges-based Drug Delivery Systems

4 citations , January 2022 in “Current pharmaceutical design”

This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.

research The clock gene brain and muscle Arnt-like protein-1 (BMAL1) is involved in hair growth

9 citations , August 2013 in “Archives of Dermatological Research”

This study concluded that the expression of clock genes, specifically BMAL1, in hair follicles is linked to circadian rhythm, and BMAL1 regulates hair growth.

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Community Join

5 / 304 results

community Korean Laser Helmet has a 44% increase in hair growth vs 0% growth in placebo in a double-blinded randomized controlled clinical trial.

3037 upvotes 11 months ago

A Korean laser helmet increases hair growth by 44% compared to a placebo. Users discuss its cost-effectiveness, clinical support, and compare it to treatments like finasteride and minoxidil, focusing on wavelength and energy density.

community Finasteride vs Dutasteride, something ain’t right.

in Finasteride/Dutasteride 31 upvotes 1 year ago

Finasteride is generally seen as more successful for hair loss than Dutasteride, with fewer negative experiences reported. Dutasteride is considered more effective but often leads to more complaints, possibly due to higher expectations or improper use.

community Low cortisol it is due the fin

7 upvotes 1 year ago

The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

community Why isn’t Clascoterone being discussed more?

5 upvotes 6 days ago

Clascoterone is seen as a promising alternative for those who can't tolerate finasteride due to side effects like reduced libido and anxiety. Users discuss using topical finasteride and minoxidil for hair maintenance and consider Clascoterone as a potential future treatment.

community Clascoterone - what we have right now

24 upvotes 7 months ago

Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

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Experts

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22
Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi