March 2023 in “Journal of Cosmetic Dermatology” A genetic variant linked to hair thinning in Japanese women was found.
November 2020 in “Journal of Pharmaceutical Sciences” The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
88 citations,
May 2020 in “Clinical therapeutics” Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.
39 citations,
September 2015 in “Clinical Therapeutics” Teriflunomide was an FDA-approved oral medication for relapsing multiple sclerosis, demonstrating significant efficacy in reducing relapse rates and disease progression in clinical trials. The 14-mg dose notably reduced the annualized relapse rate by up to 36% and decreased disability progression risk, while the 7-mg dose was less effective in preventing disability progression. MRI results supported its efficacy by showing reduced lesion volume. Common adverse events included headache, increased liver enzymes, diarrhea, and alopecia. Due to potential teratogenic effects, it was contraindicated in pregnancy, and routine monitoring was recommended. Overall, teriflunomide was considered an effective treatment option with a favorable benefit-risk profile.
10 citations,
October 2009 in “Clinical Therapeutics” Finasteride 5-mg oral disintegrating tablets and standard tablets are bioequivalent in healthy adult male Han Chinese volunteers.