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research 41261 Identification of Demographic and Clinical Features Associated with Multi-Biologic Failure in the CorEvitas Psoriasis Registry

September 2023 in “Journal of the American Academy of Dermatology”

Certain factors like being female, having high cholesterol, using Medicaid, and previous non-biologic treatments increase the risk of multiple biologic failures in psoriasis patients.

research A decade of hair-loss clinical trials: a registry-based analysis of studies registered on ClinicalTrials.gov

June 2026 in “Frontiers in Medicine”

This registry-based analysis observed rapid growth in hair-loss clinical trials between 2015 and 2025, highlighting regional concentration, prevalent therapeutic categories, and diverse outcome reporting while emphasizing the need for standardization and broader representation.

Chinese SLE Treatment and Research Group (CSTAR) Registry 2009–2019: Major Clinical Characteristics of Chinese Patients with Systemic Lupus Erythematosus

research Chinese SLE Treatment and Research group (CSTAR) registry 2009–2019: Major clinical characteristics of Chinese patients with systemic lupus erythematosus

15 citations , March 2021 in “Rheumatology and Immunology Research”

The CSTAR registry, the largest in China for SLE, reports more than 25,000 patients registered since 2009, detailing demographics, clinical characteristics, and providing data for future studies.

research COVID-19 clinical outcomes and nationality: results from a Nationwide registry in Kuwait

18 citations , September 2020 in “BMC Public Health”

This study found that non-Kuwaiti COVID-19 patients in Kuwait had higher odds of death, ICU admission, ARDS, and pneumonia compared to Kuwaiti patients.

research Clinical and sociodemographic features of alopecia areata in five Colombian cities: an analysis of the RENAAC registry

February 2024 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas”

This study reviewed 562 alopecia areata patients in Colombia, observing a higher prevalence in women and common use of steroid injections and topical minoxidil as treatments.

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community Hope Medicine announces HMI-115 phase II clinical trial for androgenetic alopecia in China

59 upvotes 3 years ago

Hope Medicine's announcement of the HMI-115 Phase II clinical trial for androgenetic alopecia in China; other related trials have been conducted or are ongoing in different countries, including Australia, US, and Europe. There is speculation that the product may be accepted across borders without additional testing.

community Who said GT20029 would be applied only few times per month?

12 upvotes 4 years ago

The conversation discusses the safety and effectiveness of a hair loss drug, GT20029, and the possibility of infrequent application, with users hoping for once-daily use and speculating on the drug's duration of effect on the scalp. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community About GT20029's Efficacy and Strength

7 upvotes 3 years ago

The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

community The 2026 Breakthrough Pipeline: Top 5 Mind-Changing Hair Loss Treatments To Watch

1 week ago

New hair loss treatments include lab-grown hair cloning, scarless healing with verteporfin, GT20029 for receptor degradation, JAK inhibitors for follicle activation, and dermal papilla stem cell exosomes. These aim to regenerate hair rather than just slow hair loss.

community Finasteride nuking 85%+ dht levels update

25 upvotes 4 months ago

The user discovered their previous hair loss medication was counterfeit and switched to Propecia, which significantly lowered their DHT levels. They plan to continue using Propecia and add oral Minoxidil to their routine for better results.

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Learn

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learn KY19382

Are there clinical studies showing that KY19382 can regrow hair in androgenic alopecia? No clinical studies have proven KY19382 regrows hair in androgenic alopecia.

learn SCUBE3

What do clinical trials say about the safety and effectiveness of SCUBE3 for hair regrowth? No clinical trial of SCUBE3 for hair regrowth has been registered on ClinicalTrials.gov or published, so there is no human safety or effectiveness data. The evidence is limited to one 2022 laboratory and mouse study reporting that SCUBE3 activates hair follicle stem cells through TGF-beta signalling.

learn Follistatin

Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

learn Tofacitinib

What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

learn GT20029

When will GT20029 be commercially available, and are there any clinical trials on its use? GT20029 is not approved or commercially available anywhere and remains investigational. A published 12-week Phase II study in 180 Chinese men reports hair-count gains over placebo, but no long-term or Phase III data exists, so any launch is years away at best.

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