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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn GT20029

      research compound made to degrade androgen receptors in scalp
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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  127 upvotes 1 year ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.
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      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 10 months ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.