research Tight Junction Barriers in Human Hair Follicles – Role of Claudin-1
Claudin-1 is important for the barrier function and growth of hair.
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research Testosterone Reduces Tight Junction Complexity and Down-Regulates Expression of Claudin-4 and Occludin in the Endometrium in Ovariectomized, Sex-Steroid Replacement Rats
Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
research Claudin Expression Modulations Reflect an Injury Response in the Murine Epidermis
Claudin expression changes help the skin respond to injury.
research Epidermis-Specific Ablation of Claudin-1 in Adult Mice Demonstrates the Essential Role of a Tight Junction Barrier in Skin Homeostasis
Claudin-1 is crucial for maintaining skin barrier and preventing inflammation.
research Estimation of Claudin 3 in the Serum of Alopecia Areata Patients and Its Association with Disease Severity
Higher Claudin 3 levels in the blood are linked to more severe alopecia areata.
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5 / 5 resultscommunity If you’ve taken oral minoxidil (Loniten), how much did you begin with? Would also love to hear your overall experience with it
User 1: Female, 24, prescribed 2.5mg oral minoxidil and 100mg spironolactone, asks about others' experiences. User 2: Male, 32, took oral minoxidil for a year, saw better results at 3.75mg, experienced thicker eyebrows, longer eyelashes, and longer body hair.
community 3 month progress.. results are in!
A 37-year-old user shared their positive 3-month progress using a topical solution of 5% minoxidil and 0.25% finasteride, combined with weekly microneedling and Nizoral shampoo. They reported no significant side effects and emphasized the importance of consistency and microneedling for hair regrowth.
community 3 months 5g Min only before/after, 26 y/o
The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.
community Increased Coffee intake resulted in massive shed
Increased coffee intake might be linked to hair shedding, but the cause is unclear. The user is on finasteride and has increased water intake, possibly affecting electrolyte balance.
community The celebrated doctors that we adore so much and whose advice we hear without doubts, are only humans after all
The user visited three dermatologists for hair loss treatment and was disappointed with their lack of thorough examination and discussion. Treatments prescribed included minoxidil, finasteride, multivitamins, ketoconazole shampoo, vitamin D3, and biotin, but the user was dissatisfied with the approach and lack of consideration for newer treatments.